B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5
about
Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1CD19 is a major B cell receptor-independent activator of MYC-driven B-lymphomagenesisThe mouse immunoglobulin heavy chain V-D intergenic sequence contains insulators that may regulate ordered V(D)J recombinationChromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites.Epigenetic control of recombination in the immune systemChromatin remodeling, DNA damage repair and aging.Localized DNA demethylation at recombination intermediates during immunoglobulin heavy chain gene assembly.Histone acetyltransferase p300 acetylates Pax5 and strongly enhances Pax5-mediated transcriptional activityDirected targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins.Cis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus.Epigenetic histone modifications do not control Igkappa locus contraction and intranuclear localization in cells with dual B cell-macrophage potential.B-Lymphoma cells with epigenetic silencing of Pax5 trans-differentiate into macrophages, but not other hematopoietic lineages.Yin Yang 1 is a critical regulator of B-cell developmentB cell activator PAX5 promotes lymphomagenesis through stimulation of B cell receptor signaling.Antisense intergenic transcription precedes Igh D-to-J recombination and is controlled by the intronic enhancer Emu.Activation of 12/23-RSS-dependent RAG cleavage by hSWI/SNF complex in the absence of transcription.Epigenetic regulation of lymphoid specific gene sets.Chromosomal position of a VH gene segment determines its activation and inactivation as a substrate for V(D)J recombination.Reciprocal patterns of methylation of H3K36 and H3K27 on proximal vs. distal IgVH genes are modulated by IL-7 and Pax5.Functional analysis of histone methyltransferase g9a in B and T lymphocytes.Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3' regulatory region of the immunoglobulin heavy chain locus.Localized epigenetic changes induced by DH recombination restricts recombinase to DJH junctionsChromatin accessibility and epigenetic modifications differ between frequently and infrequently rearranging VH genesEpigenetics of antigen-receptor gene assembly.A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement.A 220-nucleotide deletion of the intronic enhancer reveals an epigenetic hierarchy in immunoglobulin heavy chain locus activation.Changes in replication, nuclear location, and expression of the Igh locus after fusion of a pre-B cell line with a T cell line.Chromatin architecture and the generation of antigen receptor diversity.Temporal and spatial regulation of V(D)J recombination: interactions of extrinsic factors with the RAG complex.Epigenetic regulation of V(D)J recombination.The epigenetic landscape of B lymphocyte tolerance to self.Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5.FoxO1 induces Ikaros splicing to promote immunoglobulin gene recombinationEpstein-Barr virus BZLF1 protein binds to mitotic chromosomes.Purification of histone demethylases from HeLa cells.
P2860
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P2860
B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5
description
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im August 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/08/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/08/01)
@nl
наукова стаття, опублікована в серпні 2004
@uk
مقالة علمية (نشرت في أغسطس 2004)
@ar
name
B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5
@ast
B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5
@en
B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5
@nl
type
label
B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5
@ast
B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5
@en
B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5
@nl
prefLabel
B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5
@ast
B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5
@en
B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5
@nl
P2093
P2860
P356
P1433
P1476
B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5
@en
P2093
Alfred L. M. Bothwell
David G. Schatz
David G. T. Hesslein
David L. Pflugh
Kristen Johnson
Kuo-I. Lin
P2860
P304
P356
10.1038/NI1099
P407
P577
2004-08-01T00:00:00Z