Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos
about
Impaired angiogenesis and altered Notch signaling in mice overexpressing endothelial Egfl7Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitorsVascular patterning sets the stage for macro and micro hepatic architectureThe Notch pathway: a crossroad between the life and death of the endotheliumContext-specific interactions between Notch and ALK1 cannot explain ALK1-associated arteriovenous malformations.A novel function of Tis11b/BRF1 as a regulator of Dll4 mRNA 3'-end processingEndothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndromeNotch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants.Sox17 is indispensable for acquisition and maintenance of arterial identityKSHV-induced notch components render endothelial and mural cell characteristics and cell survival.Adrenomedullin as a therapeutic target in angiogenesis.A Snail1/Notch1 signalling axis controls embryonic vascular development.Selective regulation of Notch ligands during angiogenesis is mediated by vimentinDll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models.Notch signaling regulates remodeling and vessel diameter in the extraembryonic yolk sac.Bone marrow-derived endothelial progenitors expressing Delta-like 4 (Dll4) regulate tumor angiogenesis.Low-dosage inhibition of Dll4 signaling promotes wound healing by inducing functional neo-angiogenesisAngiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of beta-cateninA distinct mechanism of vascular lumen formation in Xenopus requires EGFL7Expression Pattern of Early Growth Response Gene 1 during Olive Flounder (Paralichthys olivaceus) Embryonic Development.Notch1 is pan-endothelial at the onset of flow and regulated by flow.Incomplete Dll4/Notch signaling inhibition promotes functional angiogenesis supporting the growth of skin papillomasEGFL7: a unique angiogenic signaling factor in vascular development and diseaseNotch signaling in developmental and tumor angiogenesis.Endothelial Dll4 overexpression reduces vascular response and inhibits tumor growth and metastasization in vivoPhosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo.BRG1 promotes COUP-TFII expression and venous specification during embryonic vascular development.Endothelial RAF1/ERK activation regulates arterial morphogenesis.Notch signaling in the vasculatureEndothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesisRegulating the regulators of angiogenesis by CCN1 and taking it up a NotchNotch-1 signalling is activated in brain arteriovenous malformations in humans.Polychlorinated biphenyls target Notch/Dll and VEGF R2 in the mouse placenta and human trophoblast cell lines for their anti-angiogenic effects.The Notch ligand Delta-like 4 (DLL4) as a target in angiogenesis-based cancer therapy?Endothelial signaling and the molecular basis of arteriovenous malformation.Notch regulation of tumor angiogenesis.Neovascularization and hematopoietic stem cells.Molecular pathways of notch signaling in vascular smooth muscle cells.Transcriptional regulation of endothelial cell and vascular development.Dll4-Notch signaling in regulation of tumor angiogenesis.
P2860
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P2860
Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos
description
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im September 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/09/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/09/01)
@nl
наукова стаття, опублікована у вересні 2008
@uk
مقالة علمية (نشرت في سبتمبر 2008)
@ar
name
Overexpression of delta-like 4 ...... on in developing mouse embryos
@ast
Overexpression of delta-like 4 ...... on in developing mouse embryos
@en
Overexpression of delta-like 4 ...... on in developing mouse embryos
@nl
type
label
Overexpression of delta-like 4 ...... on in developing mouse embryos
@ast
Overexpression of delta-like 4 ...... on in developing mouse embryos
@en
Overexpression of delta-like 4 ...... on in developing mouse embryos
@nl
prefLabel
Overexpression of delta-like 4 ...... on in developing mouse embryos
@ast
Overexpression of delta-like 4 ...... on in developing mouse embryos
@en
Overexpression of delta-like 4 ...... on in developing mouse embryos
@nl
P2093
P2860
P50
P921
P1433
P1476
Overexpression of delta-like 4 ...... on in developing mouse embryos
@en
P2093
Jeffrey S Scehnet
Parkash S Gill
S Ram Kumar
Weidong Jiang
P2860
P304
P356
10.1182/BLOOD-2007-09-112748
P407
P577
2008-06-17T00:00:00Z