IFN-lambda determines the intestinal epithelial antiviral host defense
about
Interferon lambda: a new sword in cancer immunotherapyEfficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potentialInnate Immunity and Immune Evasion by Enterovirus 71Knocking on Closed Doors: Host Interferons Dynamically Regulate Blood-Brain Barrier Function during Viral Infections of the Central Nervous SystemInterferon-λ: Immune Functions at Barrier Surfaces and BeyondThe regulation of inflammation by interferons and their STATsThe battle between rotavirus and its host for control of the interferon signaling pathwayInduction and function of type I and III interferon in response to viral infectionPost-transcriptional regulation of interferons and their signaling pathwaysNatural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse CytomegalovirusLeukocyte-derived IFN-α/β and epithelial IFN-λ constitute a compartmentalized mucosal defense system that restricts enteric virus infectionsTargeted induction of interferon-λ in humanized chimeric mouse liver abrogates hepatotropic virus infectionIFN-λ: A New Inducer of Local Immunity against Cancer and InfectionsInterferons and viruses: an evolutionary arms race of molecular interactionsGeneration of mouse small intestinal epithelial cell lines that allow the analysis of specific innate immune functionsSpherical lactic acid bacteria activate plasmacytoid dendritic cells immunomodulatory function via TLR9-dependent crosstalk with myeloid dendritic cellsMumps Virus Induces Protein-Kinase-R-Dependent Stress Granules, Partly Suppressing Type III Interferon Production.The immune profile associated with acute allergic asthma accelerates clearance of influenza virusInterferon induction and function at the mucosal surface.A vesicular stomatitis virus replicon-based bioassay for the rapid and sensitive determination of multi-species type I interferon.Short communication: antiviral activity of porcine IFN-λ3 against porcine epidemic diarrhea virus in vitro.Zinc is a potent and specific inhibitor of IFN-λ3 signalling.STAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity.Interferon-Lambda: A Potent Regulator of Intestinal Viral Infections.Diverse intracellular pathogens activate type III interferon expression from peroxisomesIFN-λ exerts opposing effects on T cell responses depending on the chronicity of the virus infection.Bovine type III interferon significantly delays and reduces the severity of foot-and-mouth disease in cattle.Age-dependent TLR3 expression of the intestinal epithelium contributes to rotavirus susceptibilityActivation of type III interferon genes by pathogenic bacteria in infected epithelial cells and mouse placenta.IFN-λ4: the paradoxical new member of the interferon lambda family.Interferon-λ cures persistent murine norovirus infection in the absence of adaptive immunity.Human kinome analysis reveals novel kinases contributing to virus infection and retinoic-acid inducible gene I-induced type I and type III IFN gene expression.Interferon-λ1 linked to a stabilized dimer of Fab potently enhances both antitumor and antiviral activities in targeted cells.Neonatal immune adaptation of the gut and its role during infections.Impact and regulation of lambda interferon response in human metapneumovirus infectionSuppression of interferon lambda signaling by SOCS-1 results in their excessive production during influenza virus infectionOral administration of Lactococcus lactis subsp. lactis JCM5805 enhances lung immune response resulting in protection from murine parainfluenza virus infectionIdentification of Toll-like receptor 9 as parapoxvirus ovis-sensing receptor in plasmacytoid dendritic cellsCommensal microbes and interferon-λ determine persistence of enteric murine norovirus infection.Immunology. Interfering with interferons.
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P2860
IFN-lambda determines the intestinal epithelial antiviral host defense
description
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2011
@ast
im Mai 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/05/10)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/05/10)
@nl
наукова стаття, опублікована в травні 2011
@uk
name
IFN-lambda determines the intestinal epithelial antiviral host defense
@ast
IFN-lambda determines the intestinal epithelial antiviral host defense
@en
IFN-lambda determines the intestinal epithelial antiviral host defense
@nl
type
label
IFN-lambda determines the intestinal epithelial antiviral host defense
@ast
IFN-lambda determines the intestinal epithelial antiviral host defense
@en
IFN-lambda determines the intestinal epithelial antiviral host defense
@nl
prefLabel
IFN-lambda determines the intestinal epithelial antiviral host defense
@ast
IFN-lambda determines the intestinal epithelial antiviral host defense
@en
IFN-lambda determines the intestinal epithelial antiviral host defense
@nl
P2093
P2860
P50
P3181
P356
P1476
IFN-lambda determines the intestinal epithelial antiviral host defense
@en
P2093
Claudia U. Duerr
Markus Mordstein
Mathias W. Hornef
Peter Staeheli
Tanel Mahlakõiv
P2860
P304
P3181
P356
10.1073/PNAS.1100552108
P407
P577
2011-05-10T00:00:00Z