An unbiased expression screen for synaptogenic proteins identifies the LRRTM protein family as synaptic organizers
about
Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestryMetabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion proteinSAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1LRRTMs and neuroligins bind neurexins with a differential code to cooperate in glutamate synapse developmentSingle-Cell mRNA Profiling Reveals Cell-Type-Specific Expression of Neurexin IsoformsLeucine-rich repeat transmembrane proteins are essential for maintenance of long-term potentiationMembrane-tethered monomeric neurexin LNS-domain triggers synapse formationNeuroligins/LRRTMs prevent activity- and Ca2+/calmodulin-dependent synapse elimination in cultured neuronsSynaptic cell adhesionThe neurexin ligands, neuroligins and leucine-rich repeat transmembrane proteins, perform convergent and divergent synaptic functions in vivoCalmodulin suppresses synaptotagmin-2 transcription in cortical neuronsLRRTM2 functions as a neurexin ligand in promoting excitatory synapse formationLateral organization of the postsynaptic densityOn the Teneurin track: a new synaptic organization molecule emergesOrigin and loss of nested LRRTM/α-catenin genes during vertebrate evolutionA genetically encoded tag for correlated light and electron microscopy of intact cells, tissues, and organismsN-Glycosylation at the SynCAM (Synaptic Cell Adhesion Molecule) Immunoglobulin Interface Modulates Synaptic AdhesionSlitrk1 is localized to excitatory synapses and promotes their developmentEphrin regulation of synapse formation, function and plasticityLRRTM1-deficient mice show a rare phenotype of avoiding small enclosures--a tentative mouse model for claustrophobia-like behaviour.The specific α-neurexin interactor calsyntenin-3 promotes excitatory and inhibitory synapse developmentImpaired cognitive function and altered hippocampal synapse morphology in mice lacking Lrrtm1, a gene associated with schizophreniaHigh content image analysis identifies novel regulators of synaptogenesis in a high-throughput RNAi screen of primary neuronsInteraction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse developmentA subtype-specific function for the extracellular domain of neuroligin 1 in hippocampal LTPElfn1 regulates target-specific release probability at CA1-interneuron synapsesPresynaptic targeting of alpha4beta 2 nicotinic acetylcholine receptors is regulated by neurexin-1betaActivity-dependent adaptations in inhibitory axonsA genome-wide association study of attempted suicide.Memory impairment in transgenic Alzheimer mice requires cellular prion protein.Differential regulation of the postsynaptic clustering of γ-aminobutyric acid type A (GABAA) receptors by collybistin isoforms.NOS1AP associates with Scribble and regulates dendritic spine development.In vivo physiological and transcriptional profiling reveals host responses to Clostridium difficile toxin A and toxin BMeasuring action potential-evoked transmission at individual synaptic contactsTwigs into branches: how a filopodium becomes a dendrite.A cell surface interaction network of neural leucine-rich repeat receptors.Neurodevelopmental effects of chronic exposure to elevated levels of pro-inflammatory cytokines in a developing visual system.Acute knockdown of AMPA receptors reveals a trans-synaptic signal for presynaptic maturation.Selective control of inhibitory synapse development by Slitrk3-PTPδ trans-synaptic interaction.Dynamic mechanisms of neuroligin-dependent presynaptic terminal assembly in living cortical neurons
P2860
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P248
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P2860
An unbiased expression screen for synaptogenic proteins identifies the LRRTM protein family as synaptic organizers
description
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im März 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/03/12)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/03/12)
@nl
наукова стаття, опублікована в березні 2009
@uk
مقالة علمية (نشرت في 12-3-2009)
@ar
name
An unbiased expression screen ...... family as synaptic organizers
@ast
An unbiased expression screen ...... family as synaptic organizers
@en
An unbiased expression screen ...... family as synaptic organizers
@nl
type
label
An unbiased expression screen ...... family as synaptic organizers
@ast
An unbiased expression screen ...... family as synaptic organizers
@en
An unbiased expression screen ...... family as synaptic organizers
@nl
prefLabel
An unbiased expression screen ...... family as synaptic organizers
@ast
An unbiased expression screen ...... family as synaptic organizers
@en
An unbiased expression screen ...... family as synaptic organizers
@nl
P2093
P2860
P921
P3181
P1433
P1476
An unbiased expression screen ...... family as synaptic organizers
@en
P2093
Ann Marie Craig
Frederick A. Dobie
Haakon B. Nygaard
Hideto Takahashi
Juha Laurén
Matti S. Airaksinen
Michael W. Linhoff
Robert M. Cassidy
Stephen M. Strittmatter
P2860
P304
P3181
P356
10.1016/J.NEURON.2009.01.017
P407
P577
2009-03-12T00:00:00Z