CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation
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The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cellsCD45-associated protein is not essential for the regulation of antigen receptor-mediated signal transduction77 C/G mutation in the tyrosine phosphatase CD45 gene and autoimmune hepatitis: evidence for a genetic linkCD45 phosphatase is crucial for human and murine acute myeloid leukemia maintenance through its localization in lipid raftsAuxiliary splice factor U2AF26 and transcription factor Gfi1 cooperate directly in regulating CD45 alternative splicingExpression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte developmentPhosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptorDevelopment of T-leukaemias in CD45 tyrosine phosphatase-deficient mutant lck miceImpaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient miceAnti-CD45RO suppresses human immunodeficiency virus type 1 replication in microglia: role of Hck tyrosine kinase and implications for AIDS dementia.A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activationPhosphorylation of CD45 by casein kinase 2. Modulation of activity and mutational analysis.PU.1 is a lineage-specific regulator of tyrosine phosphatase CD45.A non-cytosolic protein of Trypanosoma evansi induces CD45-dependent lymphocyte death.Altered thymic positive selection and intracellular signals in Cbl-deficient miceNovel tools to dissect the dynamic regulation of TCR signaling by the kinase Csk and the phosphatase CD45CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic developmentLigand dimensions are important in controlling NK-cell responses.A major susceptibility locus for systemic lupus erythemathosus maps to chromosome 1q31A C-type lectin collaborates with a CD45 phosphatase homolog to facilitate West Nile virus infection of mosquitoes.Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis.HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.Knockout mice: a paradigm shift in modern immunology.Dysregulation of signaling pathways in CD45-deficient NK cells leads to differentially regulated cytotoxicity and cytokine production.Temporal stability of the mouse gut microbiota in relation to innate and adaptive immunity.Integrin-mediated tyrosine phosphorylation of Shc in T cells is regulated by protein kinase C-dependent phosphorylations of LckA role for the protein tyrosine phosphatase CD45 in macrophage adhesion through the regulation of paxillin degradation.CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cellsGenome-wide mouse mutagenesis reveals CD45-mediated T cell function as critical in protective immunity to HSV-1.Clinical features and factors associated with outcomes of patients infected with a Novel Influenza A (H7N9) virus: a preliminary study.Characterization of Monoclonal Antibodies against Human Leukocyte Common Antigen (CD45)A disease-associated polymorphism alters splicing of the human CD45 phosphatase gene by disrupting combinatorial repression by heterogeneous nuclear ribonucleoproteins (hnRNPs).A high-frequency polymorphism in exon 6 of the CD45 tyrosine phosphatase gene (PTPRC) resulting in altered isoform expression.Transmission-blocking antibodies against mosquito C-type lectins for dengue prevention.Viral interference with functions of the cellular receptor tyrosine phosphatase CD45.CD45 isoform expression in microglia and inflammatory cells in HIV-1 encephalitis.Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival.The impact of alternative splicing in vivo: mouse models show the way.CD45 Isoform Profile Identifies Natural Killer (NK) Subsets with Differential Activity.Comparison of predicted and actual consequences of missense mutations.
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P2860
CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation
description
1996 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1996
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im April 1996 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 1996/04/01)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/04/01)
@nl
наукова стаття, опублікована у квітні 1996
@uk
مقالة علمية (نشرت في أبريل 1996)
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name
CD45-null transgenic mice reve ...... mocytes, and B cell maturation
@ast
CD45-null transgenic mice reve ...... mocytes, and B cell maturation
@en
CD45-null transgenic mice reve ...... mocytes, and B cell maturation
@nl
type
label
CD45-null transgenic mice reve ...... mocytes, and B cell maturation
@ast
CD45-null transgenic mice reve ...... mocytes, and B cell maturation
@en
CD45-null transgenic mice reve ...... mocytes, and B cell maturation
@nl
prefLabel
CD45-null transgenic mice reve ...... mocytes, and B cell maturation
@ast
CD45-null transgenic mice reve ...... mocytes, and B cell maturation
@en
CD45-null transgenic mice reve ...... mocytes, and B cell maturation
@nl
P2093
P2860
P921
P3181
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P1476
CD45-null transgenic mice reve ...... mocytes, and B cell maturation
@en
P2093
A. J. Smith
D. R. Alexander
K. F. Byth
L. A. Conroy
S. Howlett
P2860
P304
P3181
P356
10.1084/JEM.183.4.1707
P407
P577
1996-04-01T00:00:00Z