sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins
about
FBXW7-mediated degradation of CCDC6 is impaired by ATM during DNA damage response in lung cancer cellsSEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide productionFbxw7 regulates lipid metabolism and cell fate decisions in the mouse liverSEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradationSystematic analysis and nomenclature of mammalian F-box proteinsFbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradationMastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complexSCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysisDynamic ubiquitination of the mitogen-activated protein kinase kinase (MAPKK) Ste7 determines mitogen-activated protein kinase (MAPK) specificity.Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeastArchipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell linesType VI secretion system translocates a phage tail spike-like protein into target cells where it cross-links actinp24 proteins and quality control of LIN-12 and GLP-1 trafficking in Caenorhabditis elegansThe Arabidopsis HOBBIT gene encodes a CDC27 homolog that links the plant cell cycle to progression of cell differentiation.Turn It Down a NotchMutations in genes involved in nonsense mediated decay ameliorate the phenotype of sel-12 mutants with amber stop mutations in Caenorhabditis elegansEvidence for functional and physical association between Caenorhabditis elegans SEL-10, a Cdc4p-related protein, and SEL-12 presenilinsel-11 and cdc-42, two negative modulators of LIN-12/Notch activity in C. elegansThe Caenorhabditis elegans CDT-2 ubiquitin ligase is required for attenuation of EGFR signalling in vulva precursor cells.Arbiter of differentiation and death: Notch signaling meets apoptosis.The Caenorhabditis elegans gonad: a test tube for cell and developmental biology.Screening for small molecule inhibitors of embryonic pathways: sometimes you gotta crack a few eggs.Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain.Multilayer control of the EMT master regulators.Ubiquitin-dependent proteolysis in G1/S phase control and its relationship with tumor susceptibilityLIN-12/Notch activation leads to microRNA-mediated down-regulation of Vav in C. elegans.All good things must come to an end: how is Notch signaling turned off?Genetic analysis of Caenorhabditis elegans glp-1 mutants suggests receptor interaction or competition.A genetic screen for neurite outgrowth mutants in Caenorhabditis elegans reveals a new function for the F-box ubiquitin ligase component LIN-23Emerging molecular targets for the treatment of pre-eclampsia.F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous mannerDying for a cause: invertebrate genetics takes on human neurodegeneration.Dictyostelium amoebae lacking an F-box protein form spores rather than stalk in chimeras with wild typeebi regulates epidermal growth factor receptor signaling pathways in Drosophila.Emerging roles of the FBW7 tumour suppressor in stem cell differentiation.Fbw7/hCDC4 dimerization regulates its substrate interactionsDominant-negative mutation in the beta2 and beta6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage.Notch signaling is antagonized by SAO-1, a novel GYF-domain protein that interacts with the E3 ubiquitin ligase SEL-10 in Caenorhabditis elegansIntegrin-linked kinase controls Notch1 signaling by down-regulation of protein stability through Fbw7 ubiquitin ligaseKaposi's sarcoma herpesvirus-encoded latency-associated nuclear antigen stabilizes intracellular activated Notch by targeting the Sel10 protein.
P2860
Q24302090-90AE52C1-1901-4DCD-A130-9FFFDADA9848Q24307854-314B50C6-38B8-4AF6-9B46-43DF10E2C553Q24310626-43096EA6-74C4-4D42-A860-092776E8414CQ24548288-457C236C-E891-44B4-BDA0-BE057C072A4BQ24561715-4DFED855-CBB1-469E-946A-EB3C3B604F91Q24651352-41FC2E27-72E8-4F2F-A304-4A07B836E5FEQ24675233-9E394353-A1C2-4FB0-A56A-F5FD7F3F9CC5Q24677035-EC213DB4-DFFB-47A5-A755-61458F2A2733Q27930260-0CA58FC9-0236-4F49-9BB4-576AA01F4EE1Q27940196-201E4F6F-E300-4376-9204-729651DCB36BQ28188140-FBB73747-957B-4EAD-BD83-3CA186BCDA3BQ28485710-E4EFFFB5-1631-49FA-A4A3-53AD2E80C53EQ28619405-7CDACF8C-A98A-4693-BC5F-C13FB5E26C93Q33337774-BFE9CA3F-D55D-4729-ADC0-CC2DF206E655Q33364683-D10EE587-E573-449D-9C58-A31BFEBAEEDBQ33420094-9CC06466-D4C7-418B-B60E-66FBB94EFB73Q33613864-604C3EDA-27BA-435E-80C8-C75683FE52CCQ33649826-B7C61D3C-FAFA-46CF-A4FA-625DC44C8B0BQ33729115-33E9B5F1-7336-48DD-862B-53F3FD6EBA22Q33755151-F247631A-CD78-40A1-978B-FF385F6FCC0CQ33924971-202F7C23-0A0B-428A-9870-24D9604DE8F9Q34133507-8718FB90-7BEC-4014-B16C-9881756B2D45Q34189079-2B1077CA-2C68-4404-949D-6647B283A182Q34340552-6D3A1C65-A86A-46A6-AF21-0757F8B99A50Q34346963-0165CF37-DFB9-4669-8927-B25A58BEB4B2Q34441379-7100A456-0A1A-42F2-ADF7-297396DD76AEQ34543729-FFF06812-62B0-4E15-A9D6-4B419B9B3D3FQ34616853-9D693454-C8A9-4742-8FBE-D881A813624FQ34643870-890E8945-FD6F-4064-A684-AF87D425FB90Q35050406-C3D96179-11C4-4089-A927-19E181DADBF9Q35056718-297C704E-B2CB-4394-87CD-4EE9D83E6CA1Q35074847-3E414B58-7B77-43AF-B0C5-7B831D6D1507Q35108842-D19664F7-386D-48C5-9A81-46662017BAF5Q35194693-503BFC3F-61A7-4444-9079-D9CE5BE84EBBQ35634693-11A64657-2255-438A-9AB9-9A30B5A1A45FQ35647016-E571B0D6-275F-48BC-AB36-3C89376C59E6Q35648970-727A014C-CC8C-440F-9F59-AD9595DE157AQ35810761-A72E3A6B-A965-4BAA-96A1-434ACB226F43Q35950088-6BCF4B68-72B2-4C5C-A3FE-4F283B6E8D66Q36019173-6943FE39-6769-4703-A218-D4BAD9F76D52
P2860
sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins
description
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1997
@ast
im Dezember 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/12/01)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/12/01)
@nl
наукова стаття, опублікована в грудні 1997
@uk
научни чланак (објављен 1997/12/01)
@sr
name
sel-10, a negative regulator o ...... of the CDC4 family of proteins
@ast
sel-10, a negative regulator o ...... of the CDC4 family of proteins
@en
sel-10, a negative regulator o ...... of the CDC4 family of proteins
@nl
type
label
sel-10, a negative regulator o ...... of the CDC4 family of proteins
@ast
sel-10, a negative regulator o ...... of the CDC4 family of proteins
@en
sel-10, a negative regulator o ...... of the CDC4 family of proteins
@nl
prefLabel
sel-10, a negative regulator o ...... of the CDC4 family of proteins
@ast
sel-10, a negative regulator o ...... of the CDC4 family of proteins
@en
sel-10, a negative regulator o ...... of the CDC4 family of proteins
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
sel-10, a negative regulator o ...... of the CDC4 family of proteins
@en
P2093
P2860
P304
P3181
P356
10.1101/GAD.11.23.3182
P577
1997-12-01T00:00:00Z