Molecular cloning of a dendritic cell-associated transmembrane protein, DC-HIL, that promotes RGD-dependent adhesion of endothelial cells through recognition of heparan sulfate proteoglycans
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The Role of the IL-20 Subfamily in GlaucomaADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic propertiesThe DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell responsesOsteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activityGrowth and repair factors, osteoactivin, matrix metalloproteinase and heat shock protein 72, increase with resolution of inflammation in musculotendinous tissues in a rat model of repetitive graspingDectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor gamma chain to induce innate immune responsesMutation in osteoactivin decreases bone formation in vivo and osteoblast differentiation in vitro.Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucomaBioinformatic and statistical analysis of the optic nerve head in a primate model of ocular hypertension.Exploratory study on the effect of osteoactivin on muscle regeneration in a rat volumetric muscle loss modelIris phenotypes and pigment dispersion caused by genes influencing pigmentation.Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein.DC-HIL/glycoprotein Nmb promotes growth of melanoma in mice by inhibiting the activation of tumor-reactive T cellsDepleting syndecan-4+ T lymphocytes using toxin-bearing dendritic cell-associated heparan sulfate proteoglycan-dependent integrin ligand: a new opportunity for treating activated T cell-driven diseaseTargeted overexpression of osteoactivin in cells of osteoclastic lineage promotes osteoclastic resorption and bone loss in mice.The melanoma-associated transmembrane glycoprotein Gpnmb controls trafficking of cellular debris for degradation and is essential for tissue repairDC-HIL-expressing myelomonocytic cells are critical promoters of melanoma growth.Microarray analysis of iris gene expression in mice with mutations influencing pigmentation.Sézary syndrome cells overexpress syndecan-4 bearing distinct heparan sulfate moieties that suppress T-cell activation by binding DC-HIL and trapping TGF-beta on the cell surfaceDetermining immune components necessary for progression of pigment dispersing disease to glaucoma in DBA/2J miceGenetic dissection of the Gpnmb network in the eyeMyeloid cells' evasion of melanoma immunityDC-HIL is a negative regulator of T lymphocyte activation.Glycoprotein Nonmetastatic Melanoma B (Gpnmb)-Positive Macrophages Contribute to the Balance between Fibrosis and Fibrolysis during the Repair of Acute Liver Injury in Mice.Rapid generation of maturationally synchronized human dendritic cells: contribution to the clinical efficacy of extracorporeal photochemotherapy.Mutation in Osteoactivin Promotes Receptor Activator of NFκB Ligand (RANKL)-mediated Osteoclast Differentiation and Survival but Inhibits Osteoclast FunctionGlycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase.Clinical significance of glycoprotein nonmetastatic B and its association with HER2 in breast cancer.The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.Beneficial impact of Gpnmb and its significance as a biomarker in nonalcoholic steatohepatitisT-cell inhibitors: a bench-to-bedside review.By altering ocular immune privilege, bone marrow-derived cells pathogenically contribute to DBA/2J pigmentary glaucomaRole of human HGFIN/nmb in breast cancerPhase I/II study of the antibody-drug conjugate glembatumumab vedotin in patients with advanced melanoma.Glycoprotein non-metastatic b (GPNMB): A metastatic mediator and emerging therapeutic target in cancer.Tumor-associated macrophages as incessant builders and destroyers of the cancer stroma.Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-dependent fashion.The novel monoclonal antibody 9F5 reveals expression of a fragment of GPNMB/osteoactivin processed by furin-like protease(s) in a subpopulation of microglia in neonatal rat brain.The DC-HIL/syndecan-4 pathway regulates autoimmune responses through myeloid-derived suppressor cells.Emerging therapeutic targets in breast cancer bone metastasis.
P2860
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P2860
Molecular cloning of a dendritic cell-associated transmembrane protein, DC-HIL, that promotes RGD-dependent adhesion of endothelial cells through recognition of heparan sulfate proteoglycans
description
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im März 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/03/16)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/03/16)
@nl
наукова стаття, опублікована в березні 2001
@uk
name
Molecular cloning of a dendrit ...... heparan sulfate proteoglycans
@ast
Molecular cloning of a dendrit ...... heparan sulfate proteoglycans
@en
Molecular cloning of a dendrit ...... heparan sulfate proteoglycans
@nl
type
label
Molecular cloning of a dendrit ...... heparan sulfate proteoglycans
@ast
Molecular cloning of a dendrit ...... heparan sulfate proteoglycans
@en
Molecular cloning of a dendrit ...... heparan sulfate proteoglycans
@nl
prefLabel
Molecular cloning of a dendrit ...... heparan sulfate proteoglycans
@ast
Molecular cloning of a dendrit ...... heparan sulfate proteoglycans
@en
Molecular cloning of a dendrit ...... heparan sulfate proteoglycans
@nl
P2093
P2860
P3181
P356
P1476
Molecular cloning of a dendrit ...... heparan sulfate proteoglycans
@en
P2093
K. Ariizumi
M. Bonkobara
P. K. Zukas
S. Shikano
P2860
P304
P3181
P356
10.1074/JBC.M008539200
P407
P577
2001-03-16T00:00:00Z