Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex
about
Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability.Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's DiseaseCalcium-Sensing Receptor: A Key Target for Extracellular Calcium Signaling in NeuronsThe sodium leak channel, NALCN, in health and diseaseSodium leak channels in neuronal excitability and rhythmic behaviorsDe Novo Gene Disruptions in Children on the Autistic SpectrumA uniquely adaptable pore is consistent with NALCN being an ion sensorThe Concise Guide to PHARMACOLOGY 2013/14: ion channelsActivity-dependent adenosine release may be linked to activation of Na(+)-K(+) ATPase: an in vitro rat studyA sodium leak current regulates pacemaker activity of adult central pattern generator neurons in Lymnaea stagnalis.An inhibitory effect of extracellular Ca2+ on Ca2+-dependent exocytosis.Genomewide association study in cervical dystonia demonstrates possible association with sodium leak channel.Calcium-sensing receptor (CaSR) as a novel target for ischemic neuroprotection.NALCN ion channels have alternative selectivity filters resembling calcium channels or sodium channelsUNC79 and UNC80, putative auxiliary subunits of the NARROW ABDOMEN ion channel, are indispensable for robust circadian locomotor rhythms in DrosophilaModulation of microglial process convergence toward neuronal dendrites by extracellular calciumGd3+ and calcium sensitive, sodium leak currents are features of weak membrane-glass seals in patch clamp recordingsERK signaling mediates CaSR-promoted axon growth.Is plasma calcium concentration implicated in the development of critical illness polyneuropathy and myopathy?Strong selection for behavioural resilience in Australian stock working dogs identified by selective sweep analysis.Sodium leak channel, non-selective contributes to the leak current in human myometrial smooth muscle cells from pregnant womenCritical illness polyneuropathy (CIP) in neurological early rehabilitation: clinical and neurophysiological features.Phylogeny unites animal sodium leak channels with fungal calcium channels in an ancient, voltage-insensitive clade.Mutations in UNC80, Encoding Part of the UNC79-UNC80-NALCN Channel Complex, Cause Autosomal-Recessive Severe Infantile EncephalopathyBiallelic Mutations in UNC80 Cause Persistent Hypotonia, Encephalopathy, Growth Retardation, and Severe Intellectual DisabilityNetwork synchronization in hippocampal neuronsRegulatory inhibition of biological tissue mineralization by calcium phosphate through post-nucleation shielding by fetuin-A.Positive selection rather than relaxation of functional constraint drives the evolution of vision during chicken domestication.The cellular building blocks of breathingInvolvement of Na(+)-leak channel in substance P-induced depolarization of pacemaking activity in interstitial cells of Cajal.CLHM-1 is a functionally conserved and conditionally toxic Ca2+-permeable ion channel in Caenorhabditis elegansMutations in NALCN cause an autosomal-recessive syndrome with severe hypotonia, speech impairment, and cognitive delay.Participation of a persistent sodium current and calcium-activated nonspecific cationic current to burst generation in trigeminal principal sensory neurons.Ancient association between cation leak channels and Mid1 proteins is conserved in fungi and animals.Nimodipine-Loaded Pluronic® Block Copolymer Micelles: Preparation, Characterization, In-vitro and In-vivo Studies.NALCN: a regulator of pacemaker activity.Forward-genetics analysis of sleep in randomly mutagenized mice.Hypocalcemia-induced seizure: demystifying the calcium paradox.Targets of polyamine dysregulation in major depression and suicide: Activity-dependent feedback, excitability, and neurotransmission.SK channel inhibition mediates the initiation and amplitude modulation of synchronized burst firing in the spinal cord.
P2860
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P2860
Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex
description
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im November 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/11/04)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/11/04)
@nl
наукова стаття, опублікована в листопаді 2010
@uk
مقالة علمية (نشرت في 4-11-2010)
@ar
name
Extracellular calcium controls ...... 0-NALCN cation channel complex
@ast
Extracellular calcium controls ...... 0-NALCN cation channel complex
@en
Extracellular calcium controls ...... 0-NALCN cation channel complex
@nl
type
label
Extracellular calcium controls ...... 0-NALCN cation channel complex
@ast
Extracellular calcium controls ...... 0-NALCN cation channel complex
@en
Extracellular calcium controls ...... 0-NALCN cation channel complex
@nl
prefLabel
Extracellular calcium controls ...... 0-NALCN cation channel complex
@ast
Extracellular calcium controls ...... 0-NALCN cation channel complex
@en
Extracellular calcium controls ...... 0-NALCN cation channel complex
@nl
P2093
P2860
P921
P3181
P1433
P1476
Extracellular calcium controls ...... 0-NALCN cation channel complex
@en
P2093
Dejian Ren
Haikun Wang
Manabu Nakayama
P2860
P304
P3181
P356
10.1016/J.NEURON.2010.09.014
P407
P577
2010-11-04T00:00:00Z