Enumeration of smallest intervention strategies in genome-scale metabolic networks
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Constraint Based Modeling Going MulticellularApplications of Genome-Scale Metabolic Models in Biotechnology and Systems MedicineExact quantification of cellular robustness in genome-scale metabolic networks.In Silico Constraint-Based Strain Optimization Methods: the Quest for Optimal Cell FactoriesCyanobacterial biofuels: new insights and strain design strategies revealed by computational modelingRobOKoD: microbial strain design for (over)production of target compounds.Avoiding the Enumeration of Infeasible Elementary Flux Modes by Including Transcriptional Regulatory Rules in the Enumeration Process Saves Computational CostsEnumeration of minimal stoichiometric precursor sets in metabolic networks.Stoichiometric Representation of Gene-Protein-Reaction Associations Leverages Constraint-Based Analysis from Reaction to Gene-Level Phenotype PredictionOptimal knockout strategies in genome-scale metabolic networks using particle swarm optimizationDevelopment of a Framework for Metabolic Pathway Analysis-Driven Strain Optimization Methods.From elementary flux modes to elementary flux vectors: Metabolic pathway analysis with arbitrary linear flux constraints.Exploring complex cellular phenotypes and model-guided strain design with a novel genome-scale metabolic model of Clostridium thermocellum DSM 1313 implementing an adjustable cellulosome.Redesigning metabolism based on orthogonality principles.EColiCore2: a reference network model of the central metabolism of Escherichia coli and relationships to its genome-scale parent model.Direct calculation of minimal cut sets involving a specific reaction knock-out.Fast-SL: an efficient algorithm to identify synthetic lethal sets in metabolic networks.Growth-coupled overproduction is feasible for almost all metabolites in five major production organisms.Genome-scale strain designs based on regulatory minimal cut sets.An in-silico approach to predict and exploit synthetic lethality in cancer metabolism.Expanding Metabolic Engineering Algorithms Using Feasible Space and Shadow Price Constraint Modules.Double and multiple knockout simulations for genome-scale metabolic network reconstructionsDesigning minimal microbial strains of desired functionality using a genetic algorithm.Computational Prediction of Synthetic Lethals in Genome-Scale Metabolic Models Using Fast-SL.Conditions for duality between fluxes and concentrations in biochemical networks.Designing Optimized Production Hosts by Metabolic Modeling.A mathematical framework for yield (versus rate) optimization in constraint-based modeling and applications in metabolic engineering.COBRA methods and metabolic drug targets in cancer.Genetic Optimization Algorithm for Metabolic Engineering RevisitedDevelopment of an Integrated Framework for Minimal Cut Set Enumeration in Constraint-Based ModelsUnderstanding the evolution of functional redundancy in metabolic networks
P2860
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P2860
Enumeration of smallest intervention strategies in genome-scale metabolic networks
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Enumeration of smallest intervention strategies in genome-scale metabolic networks
@ast
Enumeration of smallest intervention strategies in genome-scale metabolic networks
@en
Enumeration of smallest intervention strategies in genome-scale metabolic networks
@nl
type
label
Enumeration of smallest intervention strategies in genome-scale metabolic networks
@ast
Enumeration of smallest intervention strategies in genome-scale metabolic networks
@en
Enumeration of smallest intervention strategies in genome-scale metabolic networks
@nl
prefLabel
Enumeration of smallest intervention strategies in genome-scale metabolic networks
@ast
Enumeration of smallest intervention strategies in genome-scale metabolic networks
@en
Enumeration of smallest intervention strategies in genome-scale metabolic networks
@nl
P2860
P3181
P1476
Enumeration of smallest intervention strategies in genome-scale metabolic networks
@en
P2093
Axel von Kamp
P2860
P304
P3181
P356
10.1371/JOURNAL.PCBI.1003378
P407
P577
2014-01-01T00:00:00Z