Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes - Test2 - elhamkhani - TriplyDB

Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes

Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes

http://www.wikidata.org/entity/Q28539874

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Candida glabrata: new tools and technologies-expanding the toolkit One small step for a yeast--microevolution within macrophages renders Candida glabrata hypervirulent due to a single point mutation New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae Widespread Inter- and Intra-Domain Horizontal Gene Transfer of d-Amino Acid Metabolism Enzymes in Eukaryotes Genome engineering in the yeast pathogen Candida glabrata using the CRISPR-Cas9 system The CCAAT-Binding Complex Controls Respiratory Gene Expression and Iron Homeostasis in Candida Glabrata.Systematic functional profiling of transcription factor networks in Cryptococcus neoformans.In vivo Candida glabrata biofilm development on foreign bodies in a rat subcutaneous model.Of mice, flies--and men? Comparing fungal infection models for large-scale screening efforts.Construction and high-throughput phenotypic screening ofZymoseptoria tritici over-expression strains.Genetic Transformation of Candida glabrata by Electroporation.Saccharomyces cerevisiae single-copy plasmids for auxotrophy compensation, multiple marker selection, and for designing metabolically cooperating communities.Comparative functional genomic screens of three yeast deletion collections reveal unexpected effects of genotype in response to diverse stress.High-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistance.The CgHaa1-Regulon Mediates Response and Tolerance to Acetic Acid Stress in the Human Pathogen Candida glabrata.Intracellular survival of Candida glabrata in macrophages: immune evasion and persistence.Beyond Candida albicans: Mechanisms of immunity to non-albicans Candida species Evolution of regulatory networks in Candida glabrata: learning to live with the human host.Biofilm formation in Candida glabrata: What have we learnt from functional genomics approaches?The birth of a deadly yeast: tracing the evolutionary emergence of virulence traits in Candida glabrata.Drug resistance mechanisms and their regulation in non-albicans Candida species.Microarray Technologies in Fungal Diagnostics.Genetic Drivers of Multidrug Resistance in Candida glabrata.A Novel Hybrid Iron Regulation Network Combines Features from Pathogenic and Nonpathogenic Yeasts The Phosphoinositide 3-Kinase Regulates Retrograde Trafficking of the Iron Permease CgFtr1 and Iron Homeostasis in Candida glabrata.Phytotherapy as an alternative to conventional antimicrobials: combating microbial resistance.The Fungal Pathogen Candida glabrata Does Not Depend on Surface Ferric Reductases for Iron Acquisition.Identification of Genes in Candida glabrata Conferring Altered Responses to Caspofungin, a Cell Wall Synthesis Inhibitor.Candida glabrata susceptibility to antifungals and phagocytosis is modulated by acetate.Next-generation sequencing offers new insights into the resistance of Candida spp. to echinocandins and azoles.Genetic Transformation of Candida glabrata by Heat Shock.Large-scale Phenotypic Profiling of Gene Deletion Mutants in Candida glabrata.Deletion of the DNA Ligase IV Gene in Candida glabrata Significantly Increases Gene-Targeting Efficiency Bartender: a fast and accurate clustering algorithm to count barcode reads.Evolutionary analysis of multidrug resistance genes in fungi - impact of gene duplication and family conservation.Chemogenomic profiling of the fungal pathogen Candida albicans.Investigation of Candida parapsilosis virulence regulatory factors during host-pathogen interaction.Galleria mellonella as a host model to study Candida glabrata virulence and antifungal efficacy.Systematic Gene-to-Phenotype Arrays: A High-Throughput Technique for Molecular Phenotyping.Remodeling of the Candida glabrata cell wall in the gastrointestinal tract affects the gut microbiota and the immune response.

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Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes

http://www.wikidata.org/entity/Q28539874

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2014年の論文

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P2860

Genome evolution in yeasts

PhylomeDB v3.0: an expanding repository of genome-wide collections of trees, alignments and phylogeny-based orthology and paralogy predictions

Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence

A nuclear receptor-like pathway regulating multidrug resistance in fungi

EMBOSS: the European Molecular Biology Open Software Suite

Functional profiling of the Saccharomyces cerevisiae genome

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

Pkh1 and Pkh2 differentially phosphorylate and activate Ypk1 and Ykr2 and define protein kinase modules required for maintenance of cell wall integrity.

Cbk1 regulation of the RNA-binding protein Ssd1 integrates cell fate with translational control

The Cbk1p pathway is important for polarized cell growth and cell separation in Saccharomyces cerevisiae

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Candida glabrata

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