CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome

CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome

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http://www.wikidata.org/entity/Q28542611
Genome Engineering with TALE and CRISPR Systems in NeuroscienceThe Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular MorphogenesisPrion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain TissueThe N-terminus of the prion protein is a toxic effector regulated by the C-terminus.Manipulating the Prion Protein Gene Sequence and Expression Levels with CRISPR/Cas9.The Human Tau Interactome: Binding to the Ribonucleoproteome, and Impaired Binding of the Proline-to-Leucine Mutant at Position 301 (P301L) to Chaperones and the Proteasome.Membrane-enriched proteome changes and prion protein expression during neural differentiation and in neuroblastoma cells.Physiological Functions of the Cellular Prion Protein.α-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication.Proteomics in the genome engineering era.A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition.Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers.Time-course global proteome analyses reveal an inverse correlation between Aβ burden and immunoglobulin M levels in the APPNL-F mouse model of Alzheimer disease.Towards authentic transgenic mouse models of heritable PrP prion diseases.The prion protein is embedded in a molecular environment that modulates transforming growth factor β and integrin signaling.
P2860

CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome

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http://www.wikidata.org/entity/Q28542611
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2014 nî lūn-bûn
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2014 թուականին հրատարակուած գիտական յօդուած
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2014 թվականին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome
@ast
CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome
@en
CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome
@nl
type
label
CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome
@ast
CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome
@en
CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome
@nl
prefLabel
CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome
@ast
CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome
@en
CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome
@nl
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P3181
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P433
P478
P50
P577
P5875
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P3181
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P1476
CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome
@en
P2093
P2860
P304
P31
P3181
P356
10.1371/JOURNAL.PONE.0114594
P407
P433
P478
P50
P577
P5875
P698
P921
P932