Melarsoprol sensitivity profile of Trypanosoma brucei gambiense isolates from cured and relapsed sleeping sickness patients from the Democratic Republic of the Congo

Melarsoprol sensitivity profile of Trypanosoma brucei gambiense isolates from cured and relapsed sleeping sickness patients from the Democratic Republic of the Congo

Item
http://www.wikidata.org/entity/Q28543489
Transport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma bruceiDrug resistance in eukaryotic microorganisms.Chimerization at the AQP2-AQP3 locus is the genetic basis of melarsoprol-pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates.Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity.Whole genome sequencing shows sleeping sickness relapse is due to parasite regrowth and not reinfection.Comparative genomics of drug resistance in Trypanosoma brucei rhodesiense.Functional analysis of drug resistance-associated mutations in the Trypanosoma brucei adenosine transporter 1 (TbAT1) and the proposal of a structural model for the protein.APOLs with low pH dependence can kill all African trypanosomes.Could specific cell targeting overcome resistance associated with current treatments for African trypanosomiasis?Isometamidium chloride and homidium chloride fail to cure mice infected with Ethiopian Trypanosoma evansi type A and B
P2860

Melarsoprol sensitivity profile of Trypanosoma brucei gambiense isolates from cured and relapsed sleeping sickness patients from the Democratic Republic of the Congo

Item
http://www.wikidata.org/entity/Q28543489
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
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2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
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2014年論文
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2014年论文
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name
Melarsoprol sensitivity profil ...... mocratic Republic of the Congo
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Melarsoprol sensitivity profil ...... mocratic Republic of the Congo
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Melarsoprol sensitivity profil ...... mocratic Republic of the Congo
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type
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Melarsoprol sensitivity profil ...... mocratic Republic of the Congo
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Melarsoprol sensitivity profil ...... mocratic Republic of the Congo
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Melarsoprol sensitivity profil ...... mocratic Republic of the Congo
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Melarsoprol sensitivity profil ...... mocratic Republic of the Congo
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Melarsoprol sensitivity profil ...... mocratic Republic of the Congo
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Melarsoprol sensitivity profil ...... mocratic Republic of the Congo
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Melarsoprol sensitivity profil ...... mocratic Republic of the Congo
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P2860
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P356
10.1371/JOURNAL.PNTD.0003212
P407
P433
P478
P50
P577
P5875
P698
P921
P932