Molecular Determinants Underlying Binding Specificities of the ABL Kinase Inhibitors: Combining Alanine Scanning of Binding Hot Spots with Network Analysis of Residue Interactions and Coevolution

Molecular Determinants Underlying Binding Specificities of the ABL Kinase Inhibitors: Combining Alanine Scanning of Binding Hot Spots with Network Analysis of Residue Interactions and Coevolution

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http://www.wikidata.org/entity/Q28548366
Molecular dynamics simulations and modelling of the residue interaction networks in the BRAF kinase complexes with small molecule inhibitors: probing the allosteric effects of ligand-induced kinase dimerization and paradoxical activation.Exploring Molecular Mechanisms of Paradoxical Activation in the BRAF Kinase Dimers: Atomistic Simulations of Conformational Dynamics and Modeling of Allosteric Communication Networks and Signaling Pathways.Computational Analysis of Residue Interaction Networks and Coevolutionary Relationships in the Hsp70 Chaperones: A Community-Hopping Model of Allosteric Regulation and CommunicationEvolutionary, computational, and biochemical studies of the salicylaldehyde dehydrogenases in the naphthalene degradation pathway.Ensemble-based modeling and rigidity decomposition of allosteric interaction networks and communication pathways in cyclin-dependent kinases: Differentiating kinase clients of the Hsp90-Cdc37 chaperone.c-Abl and Parkinson's Disease: Mechanisms and Therapeutic Potential.Protein Kinase Targets in Breast Cancer.Integrative View of the Diversity and Evolution of SWEET and SemiSWEET Sugar Transporters.Network-based modelling and percolation analysis of conformational dynamics and activation in the CDK2 and CDK4 proteins: dynamic and energetic polarization of the kinase lobes may determine divergence of the regulatory mechanisms.CBT profiles of cabozantinib approved for advanced renal cell carcinomas.Network Analysis of RAD51 Proteins in Metazoa and the Evolutionary Relationships With Their Archaeal Homologs
P2860

Molecular Determinants Underlying Binding Specificities of the ABL Kinase Inhibitors: Combining Alanine Scanning of Binding Hot Spots with Network Analysis of Residue Interactions and Coevolution

Item
http://www.wikidata.org/entity/Q28548366
description
2015 nî lūn-bûn
@nan
2015 թուականին հրատարակուած գիտական յօդուած
@hyw
2015 թվականին հրատարակված գիտական հոդված
@hy
2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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name
Molecular Determinants Underly ...... e Interactions and Coevolution
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Molecular Determinants Underly ...... e Interactions and Coevolution
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Molecular Determinants Underly ...... e Interactions and Coevolution
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type
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Molecular Determinants Underly ...... e Interactions and Coevolution
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Molecular Determinants Underly ...... e Interactions and Coevolution
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Molecular Determinants Underly ...... e Interactions and Coevolution
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prefLabel
Molecular Determinants Underly ...... e Interactions and Coevolution
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Molecular Determinants Underly ...... e Interactions and Coevolution
@en
Molecular Determinants Underly ...... e Interactions and Coevolution
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Molecular Determinants Underly ...... e Interactions and Coevolution
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10.1371/JOURNAL.PONE.0130203
P407
P433
P478
P50
P577
P5875
P698
P921
P932