Establishment of a Predictive In Vitro Assay for Assessment of the Hepatotoxic Potential of Oligonucleotide Drugs
about
Inhibition of EGF Uptake by Nephrotoxic Antisense Drugs In Vitro and Implications for Preclinical Safety Profiling.Locked nucleic acid (LNA): Based single-stranded oligonucleotides are not genotoxic.Managing the sequence-specificity of antisense oligonucleotides in drug discovery.Strategies for In Vivo Screening and Mitigation of Hepatotoxicity Associated with Antisense Drugs.Assessing single-stranded oligonucleotide drug-induced effects in vitro reveals key risk factors for thrombocytopenia.A Sensitive In Vitro Approach to Assess the Hybridization-Dependent Toxic Potential of High Affinity Gapmer Oligonucleotides.Identifying and avoiding off-target effects of RNase H-dependent antisense oligonucleotides in mice.
P2860
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P2860
Establishment of a Predictive In Vitro Assay for Assessment of the Hepatotoxic Potential of Oligonucleotide Drugs
description
2016 nî lūn-bûn
@nan
2016 թուականին հրատարակուած գիտական յօդուած
@hyw
2016 թվականին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Establishment of a Predictive ...... ntial of Oligonucleotide Drugs
@ast
Establishment of a Predictive ...... ntial of Oligonucleotide Drugs
@en
Establishment of a Predictive ...... ntial of Oligonucleotide Drugs
@nl
type
label
Establishment of a Predictive ...... ntial of Oligonucleotide Drugs
@ast
Establishment of a Predictive ...... ntial of Oligonucleotide Drugs
@en
Establishment of a Predictive ...... ntial of Oligonucleotide Drugs
@nl
prefLabel
Establishment of a Predictive ...... ntial of Oligonucleotide Drugs
@ast
Establishment of a Predictive ...... ntial of Oligonucleotide Drugs
@en
Establishment of a Predictive ...... ntial of Oligonucleotide Drugs
@nl
P2093
P2860
P3181
P1433
P1476
Establishment of a Predictive ...... ntial of Oligonucleotide Drugs
@en
P2093
Adrian B Roth
Annie Moisan
Cristina Bertinetti-Lapatki
Franz Schuler
Franziska Boess
Maj Hedtjaern
Sabine Sewing
Tanja Minz
Thomas Singer
Yann Tessier
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0159431
P407
P577
2016-01-01T00:00:00Z