KRAB-independent suppression of neoplastic cell growth by the novel zinc finger transcription factor KS1
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Novel human BTB/POZ domain-containing zinc finger protein ZBTB1 inhibits transcriptional activities of CREA functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growthFunctional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoterSequence-specific transcriptional repression by KS1, a multiple-zinc-finger-Krüppel-associated box proteinIntestinal-enriched Krüppel-like factor (Krüppel-like factor 5) is a positive regulator of cellular proliferationKRAB-containing zinc-finger repressor proteinsInhibition of cell transformation by sulindac sulfide is confined to specific oncogenic pathwaysKrüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young.Single and combinatorial chromatin coupling events underlies the function of transcript factor Krüppel-like factor 11 in the regulation of gene networks.MAGE I transcription factors regulate KAP1 and KRAB domain zinc finger transcription factor mediated gene repressionThe Sp1-like protein BTEB3 inhibits transcription via the basic transcription element box by interacting with mSin3A and HDAC-1 co-repressors and competing with Sp1.Functional dissection of transcription factor ZBRK1 reveals zinc fingers with dual roles in DNA-binding and BRCA1-dependent transcriptional repression.Krüppel-like factor 5 mediates the transforming activity of oncogenic H-RasTetrameric oligomerization mediates transcriptional repression by the BRCA1-dependent Kruppel-associated box-zinc finger protein ZBRK1.Zinc-finger protein 545 inhibits cell proliferation as a tumor suppressor through inducing apoptosis and is disrupted by promoter methylation in breast cancer.Krüppel-like factor 5 promotes mitosis by activating the cyclin B1/Cdc2 complex during oncogenic Ras-mediated transformation.Overexpression of the human ZNF300 gene enhances growth and metastasis of cancer cells through activating NF-kB pathwayDetailed structural-functional analysis of the Krüppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinologySequence-specific recruitment of heterochromatin protein 1 via interaction with Krüppel-like factor 11, a human transcription factor involved in tumor suppression and metabolic diseasesAn mSin3A interaction domain links the transcriptional activity of KLF11 with its role in growth regulation.Analysis of gene expression in Egr-1 transfected human fibrosarcoma cells.KLF11 epigenetically regulates glycodelin-A, a marker of endometrial biology via histone-modifying chromatin mechanisms.The transcriptional repressor K-RBP modulates RTA-mediated transactivation and lytic replication of Kaposi's sarcoma-associated herpesvirus.MAGE proteins regulate KRAB zinc finger transcription factors and KAP1 E3 ligase activity.Overexpression of zinc-finger protein 777 (ZNF777) inhibits proliferation at low cell density through down-regulation of FAM129A.The novel 19q13 KRAB zinc-finger tumour suppressor ZNF382 is frequently methylated in oesophageal squamous cell carcinoma and antagonises Wnt/β-catenin signalling.
P2860
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P2860
KRAB-independent suppression of neoplastic cell growth by the novel zinc finger transcription factor KS1
description
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Dezember 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/12/01)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/12/01)
@nl
наукова стаття, опублікована в грудні 1998
@uk
مقالة علمية (نشرت في ديسمبر 1998)
@ar
name
KRAB-independent suppression o ...... inger transcription factor KS1
@ast
KRAB-independent suppression o ...... inger transcription factor KS1
@en
KRAB-independent suppression o ...... inger transcription factor KS1
@nl
type
label
KRAB-independent suppression o ...... inger transcription factor KS1
@ast
KRAB-independent suppression o ...... inger transcription factor KS1
@en
KRAB-independent suppression o ...... inger transcription factor KS1
@nl
prefLabel
KRAB-independent suppression o ...... inger transcription factor KS1
@ast
KRAB-independent suppression o ...... inger transcription factor KS1
@en
KRAB-independent suppression o ...... inger transcription factor KS1
@nl
P2093
P2860
P356
P1476
KRAB-independent suppression o ...... inger transcription factor KS1
@en
P2093
B. Gebelein
M. Fernandez-Zapico
R. Urrutia
P2860
P304
P356
10.1172/JCI1919
P407
P577
1998-12-01T00:00:00Z