Regulation of the desensitization and ion selectivity of ATP-gated P2X2 channels by phosphoinositides
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Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2Molecular and functional properties of P2X receptors--recent progress and persisting challengesPhosphoinositides: tiny lipids with giant impact on cell regulationCharacterization of ATPase Activity of P2RX2 Cation ChannelA dual polybasic motif determines phosphoinositide binding and regulation in the P2X channel familyProperties of ATP-gated ion channels assembled from P2X2 subunits in mouse cochlear Reissner's membrane epithelial cells.Modeling and analysis of the molecular basis of pain in sensory neurons.Molecular characterization and expression analysis of ATP-gated P2X7 receptor involved in Japanese flounder (Paralichthys olivaceus) innate immune response.Gintonin, a ginseng-derived lysophosphatidic acid receptor ligand, potentiates ATP-gated P2X₁ receptor channel currentsActivation and regulation of purinergic P2X receptor channelsPhosphoinositides regulate ion channels.Responses of rat P2X2 receptors to ultrashort pulses of ATP provide insights into ATP binding and channel gatingAllosteric modulation of ATP-gated P2X receptor channelsPhosphoinositide signaling in somatosensory neuronsVoltage- and [ATP]-dependent gating of the P2X(2) ATP receptor channel.Phosphoinositides regulate P2X4 ATP-gated channels through direct interactions.Co-localization of Pirt protein and P2X2 receptors in the mouse enteric nervous system.Subtype-specific regulation of P2X3 and P2X2/3 receptors by phosphoinositides in peripheral nociceptors.Dynamic aspects of functional regulation of the ATP receptor channel P2X2.Channelopathies linked to plasma membrane phosphoinositides.Regulation of ion channels by membrane lipids.Post-translational regulation of P2X receptor channels: modulation by phospholipidsKey sites for P2X receptor function and multimerization: overview of mutagenesis studies on a structural basis.Lipid raft association and cholesterol sensitivity of P2X1-4 receptors for ATP: chimeras and point mutants identify intracellular amino-terminal residues involved in lipid regulation of P2X1 receptors.Control of voltage-gated K+ channel permeability to NMDG+ by a residue at the outer pore.The intracellular amino terminus plays a dominant role in desensitization of ATP-gated P2X receptor ion channels.Direct modulation of P2X1 receptor-channels by the lipid phosphatidylinositol 4,5-bisphosphateUse of chimeras, point mutants, and molecular modeling to map the antagonist-binding site of 4,4',4″,4‴-(carbonylbis-(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakisbenzene-1,3-disulfonic acid (NF449) at P2X1 receptors for ATP.Mass spectrometry analysis of human P2X1 receptors; insight into phosphorylation, modelling and conformational changes.The C-terminal Src inhibitory kinase (Csk)-mediated tyrosine phosphorylation is a novel molecular mechanism to limit P2X3 receptor function in mouse sensory neurons.Functional and structural identification of amino acid residues of the P2X2 receptor channel critical for the voltage- and [ATP]-dependent gating.Cyclin-dependent kinase 5 modulates the P2X2a receptor channel gating through phosphorylation of C-terminal threonine 372.Allostery revealed within lipid binding events to membrane proteins.Opposing Roles of Calcium and Intracellular ATP on Gating of the Purinergic P2X2 Receptor Channel.
P2860
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P2860
Regulation of the desensitization and ion selectivity of ATP-gated P2X2 channels by phosphoinositides
description
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Oktober 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/10/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/10/01)
@nl
наукова стаття, опублікована в жовтні 2006
@uk
مقالة علمية (نشرت في أكتوبر 2006)
@ar
name
Regulation of the desensitizat ...... channels by phosphoinositides
@ast
Regulation of the desensitizat ...... channels by phosphoinositides
@en
Regulation of the desensitizat ...... channels by phosphoinositides
@nl
type
label
Regulation of the desensitizat ...... channels by phosphoinositides
@ast
Regulation of the desensitizat ...... channels by phosphoinositides
@en
Regulation of the desensitizat ...... channels by phosphoinositides
@nl
prefLabel
Regulation of the desensitizat ...... channels by phosphoinositides
@ast
Regulation of the desensitizat ...... channels by phosphoinositides
@en
Regulation of the desensitizat ...... channels by phosphoinositides
@nl
P2860
P3181
P1476
Regulation of the desensitizat ...... channels by phosphoinositides
@en
P2093
Yoshihiro Kubo
Yuichiro Fujiwara
P2860
P304
P3181
P356
10.1113/JPHYSIOL.2006.115246
P407
P577
2006-10-01T00:00:00Z