In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis
about
Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's diseaseTAT-mediated intracellular delivery of purine nucleoside phosphorylase corrects its deficiency in miceInhibition of mitochondrial neural cell death pathways by protein transduction of Bcl-2 family proteinsPharmacological manipulation of cell death: clinical applications in sight?Intracellular targeting with engineered proteinsInhibition of regulated cell death by cell-penetrating peptidesApplications and Challenges for Use of Cell-Penetrating Peptides as Delivery Vectors for Peptide and Protein CargosDerivation of injury-responsive dendritic cells for acute brain targeting and therapeutic protein delivery in the stroke-injured ratExcision of HIV-1 proviral DNA by recombinant cell permeable tre-recombinaseIn vivo imaging of brain ischemia using an oxygen-dependent degradative fusion protein probeMyocyte enhancer factor 2C as a neurogenic and antiapoptotic transcription factor in murine embryonic stem cellsFacile Attachment of TAT Peptide on Gold Monolayer Protected Clusters: Synthesis and CharacterizationCell Permeable Peptides: A Promising Tool to Deliver Neuroprotective Agents in the Brain.Internalization of novel non-viral vector TAT-streptavidin into human cells.PICK1 uncoupling from mGluR7a causes absence-like seizures.Plasmalemmal vesicle associated protein-1 (PV-1) is a marker of blood-brain barrier disruption in rodent models.Efficient CPP-mediated Cre protein delivery to developing and adult CNS tissuesEthyl pyruvate protects against hypoxic-ischemic brain injury via anti-cell death and anti-inflammatory mechanisms.Design and evaluation of EphrinA1 mutants with cerebral protective effect.HSP27 protects the blood-brain barrier against ischemia-induced loss of integrity.Enhanced Delivery of Erythropoietin Across the Blood-Brain Barrier for Neuroprotection against Ischemic Neuronal Injury.CNS delivery via adsorptive transcytosis.Lack of neuroprotection of inhibitory peptides targeting Jun/JNK after transient focal cerebral ischemia in spontaneously hypertensive rats.Tat-Mediated Peptide Intervention in Analgesia and Anesthesia.Agile delivery of protein therapeutics to CNSLipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicityIncreased delivery of TAT across an endothelial monolayer following ischemic injury.Cell penetrating peptide inhibitors of nuclear factor-kappa B.TAT opens the door.Protection against ischemic brain injury by protein therapeutics.Analysis of BH3-only proteins upregulated in response to oxygen/glucose deprivation in cortical neurons identifies Bmf but not Noxa as potential mediator of neuronal injury.Absence of TLR4 reduces neurovascular unit and secondary inflammatory process after traumatic brain injury in miceNeuronal NAMPT is released after cerebral ischemia and protects against white matter injuryEffect of hypoxia on expression of selected proteins involved in regulation of apoptotic activity in striatum of newborn piglets.Peroxiredoxin-2 protects against 6-hydroxydopamine-induced dopaminergic neurodegeneration via attenuation of the apoptosis signal-regulating kinase (ASK1) signaling cascade.Cardiomyopathy of Friedreich's ataxia: use of mouse models to understand human disease and guide therapeutic development.Characterisation of cell-penetrating peptide-mediated peptide deliveryCell-free production of transducible transcription factors for nuclear reprogramming.Neuroprotective effect of TAT-14-3-3ε fusion protein against cerebral ischemia/reperfusion injury in ratsBiological applications of protein transduction technology.
P2860
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P2860
In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis
description
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im Juli 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/07/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/07/01)
@nl
наукова стаття, опублікована в липні 2002
@uk
مقالة علمية نشرت في يوليو 2002 حول موضوع: دماغ
@ar
name
In Vivo Delivery of a Bcl-xL F ...... Injury and Neuronal Apoptosis
@ast
In Vivo Delivery of a Bcl-xL F ...... Injury and Neuronal Apoptosis
@en
In Vivo Delivery of a Bcl-xL F ...... Injury and Neuronal Apoptosis
@nl
type
label
In Vivo Delivery of a Bcl-xL F ...... Injury and Neuronal Apoptosis
@ast
In Vivo Delivery of a Bcl-xL F ...... Injury and Neuronal Apoptosis
@en
In Vivo Delivery of a Bcl-xL F ...... Injury and Neuronal Apoptosis
@nl
prefLabel
In Vivo Delivery of a Bcl-xL F ...... Injury and Neuronal Apoptosis
@ast
In Vivo Delivery of a Bcl-xL F ...... Injury and Neuronal Apoptosis
@en
In Vivo Delivery of a Bcl-xL F ...... Injury and Neuronal Apoptosis
@nl
P2093
P3181
P1476
In Vivo Delivery of a Bcl-xL F ...... Injury and Neuronal Apoptosis
@en
P2093
Frank R Sharp
Guodong Cao
Hailiang Ge
Qinhua Liang
Ruiqiong Ran
Steven H Graham
P304
P3181
P356
10.1523/JNEUROSCI.22-13-05423.2002
P407
P577
2002-07-01T00:00:00Z