Mitochondrial GTP regulates glucose-stimulated insulin secretion
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Phosphoenolpyruvate cycling via mitochondrial phosphoenolpyruvate carboxykinase links anaplerosis and mitochondrial GTP with insulin secretionMetabolomics applied to the pancreatic isletCommon defects of mitochondria and iron in neurodegeneration and diabetes (MIND): a paradigm worth exploringMitochondrial regulation of β-cell function: maintaining the momentum for insulin releaseThe mitochondrial isoform of phosphoenolpyruvate carboxykinase (PEPCK-M) and glucose homeostasis: has it been overlooked?Mitochondria and cancerReduced basal ATP synthetic flux of skeletal muscle in patients with previous acromegalyAn ATP and oxalate generating variant tricarboxylic acid cycle counters aluminum toxicity in Pseudomonas fluorescens.The ATP/DNA ratio is a better indicator of islet cell viability than the ADP/ATP ratio.Mitochondrial metabolism of pyruvate is essential for regulating glucose-stimulated insulin secretionThe mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion.Regulation of insulin secretion: role of mitochondrial signalling.Glucose sensing in the pancreatic beta cell: a computational systems analysis.Comparative Analysis of the Mitochondrial Physiology of Pancreatic β CellsMitochondrial GTP insensitivity contributes to hypoglycemia in hyperinsulinemia hyperammonemia by inhibiting glucagon release.Fe-S cluster biogenesis in isolated mammalian mitochondria: coordinated use of persulfide sulfur and iron and requirements for GTP, NADH, and ATP.Mitochondrial approaches to protect against cardiac ischemia and reperfusion injury.A role for cytosolic isocitrate dehydrogenase as a negative regulator of glucose signaling for insulin secretion in pancreatic ß-cells.Regulation of glutamate metabolism and insulin secretion by glutamate dehydrogenase in hypoglycemic children.Phospholipid hydrolysis and insulin secretion: a step toward solving the Rubik's cube.The structure and allosteric regulation of mammalian glutamate dehydrogenase.Emerging roles for protein histidine phosphorylation in cellular signal transduction: lessons from the islet beta-cell.Measurement of the Absolute Magnitude and Time Courses of Mitochondrial Membrane Potential in Primary and Clonal Pancreatic Beta-Cells.Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cellsThymoquinone, a bioactive component of Nigella sativa, normalizes insulin secretion from pancreatic β-cells under glucose overload via regulation of malonyl-CoAPerspective on the Genetics and Diagnosis of Congenital Hyperinsulinism DisordersMetabolome response to glucose in the β-cell line INS-1 832/13.PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells.Metabolic cycling in control of glucose-stimulated insulin secretionArgininosuccinate synthetase regulates hepatic AMPK linking protein catabolism and ureagenesis to hepatic lipid metabolism.Mitochondrial energetics and insulin resistance.Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylasesRNA-seq analysis of the hypothalamic transcriptome reveals the networks regulating physiopathological progress in the diabetic GK rat.Loss of coupling between calcium influx, energy consumption and insulin secretion associated with development of hyperglycaemia in the UCD-T2DM rat model of type 2 diabetes.Mitochondrial glutamate carrier GC1 as a newly identified player in the control of glucose-stimulated insulin secretion.Metabolomics applied to diabetes research: moving from information to knowledgeScreen for abnormal mitochondrial phenotypes in mouse embryonic stem cells identifies a model for succinyl-CoA ligase deficiency and mtDNA depletion.A role for mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) in the regulation of hepatic gluconeogenesis.The structure and allosteric regulation of glutamate dehydrogenase.The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism: Going round in circles?
P2860
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P2860
Mitochondrial GTP regulates glucose-stimulated insulin secretion
description
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
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im April 2007 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2007/04/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/04/01)
@nl
наукова стаття, опублікована у квітні 2007
@uk
مقالة علمية (نشرت في أبريل 2007)
@ar
name
Mitochondrial GTP regulates glucose-stimulated insulin secretion
@ast
Mitochondrial GTP regulates glucose-stimulated insulin secretion
@en
Mitochondrial GTP regulates glucose-stimulated insulin secretion
@nl
type
label
Mitochondrial GTP regulates glucose-stimulated insulin secretion
@ast
Mitochondrial GTP regulates glucose-stimulated insulin secretion
@en
Mitochondrial GTP regulates glucose-stimulated insulin secretion
@nl
prefLabel
Mitochondrial GTP regulates glucose-stimulated insulin secretion
@ast
Mitochondrial GTP regulates glucose-stimulated insulin secretion
@en
Mitochondrial GTP regulates glucose-stimulated insulin secretion
@nl
P2093
P2860
P921
P3181
P1433
P1476
Mitochondrial GTP regulates glucose-stimulated insulin secretion
@en
P2093
Anthony J. Romanelli
Claes B. Wollheim
Gary W. Cline
Rebecca L. Pongratz
Richard G. Kibbey
P2860
P304
P3181
P356
10.1016/J.CMET.2007.02.008
P577
2007-04-01T00:00:00Z