Scaffolding of Fyn kinase to the NMDA receptor determines brain region sensitivity to ethanol.
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Glutamatergic substrates of drug addiction and alcoholismEthanol induces cell-cycle activity and reduces stem cell diversity to alter both regenerative capacity and differentiation potential of cerebral cortical neuroepithelial precursors.Glucocorticoid and polyamine interactions in the plasticity of glutamatergic synapses that contribute to ethanol-associated dependence and neuronal injuryCross-Species Integrative Functional Genomics in GeneWeaver Reveals a Role for Pafah1b1 in Altered Response to Alcohol.Structure of human Rack1 protein at a resolution of 2.45 ÅThinking after Drinking: Impaired Hippocampal-Dependent Cognition in Human Alcoholics and Animal Models of Alcohol DependenceAlcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase.Prion protein is a key determinant of alcohol sensitivity through the modulation of N-methyl-D-aspartate receptor (NMDAR) activityRACK1, A multifaceted scaffolding protein: Structure and function.Long-lasting adaptations of the NR2B-containing NMDA receptors in the dorsomedial striatum play a crucial role in alcohol consumption and relapse.RACK1 associates with muscarinic receptors and regulates M(2) receptor traffickingEscalating ethanol intake is associated with altered corticostriatal BDNF expressionFyn kinase and NR2B-containing NMDA receptors regulate acute ethanol sensitivity but not ethanol intake or conditioned reward.Inhibition of NR2B phosphorylation restores alterations in NMDA receptor expression and improves functional recovery following traumatic brain injury in miceLong-term ethanol and corticosterone co-exposure sensitize the hippocampal ca1 region pyramidal cells to insult during ethanol withdrawal in an NMDA GluN2B subunit-dependent manner.Signaling cascades regulating NMDA receptor sensitivity to ethanol.The neurobiology of alcohol consumption and alcoholism: an integrative historyProtein kinases and addiction.Ethanol acutely inhibits ionotropic glutamate receptor-mediated responses and long-term potentiation in the developing CA1 hippocampus.Habitual alcohol seeking: modeling the transition from casual drinking to addiction.Inhibition by ethanol of NMDA-induced responses and acute tolerance to the inhibition in rat sympathetic preganglionic neurons in vitro and in vivo.Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner.Functional adaptation of the N-methyl-D-aspartate receptor to inhibition by ethanol is modulated by striatal-enriched protein tyrosine phosphatase and p38 mitogen-activated protein kinase.Ethanol-induced increase in Fyn kinase activity in the dorsomedial striatum is associated with subcellular redistribution of protein tyrosine phosphatase αEthanol-mediated long-lasting adaptations of the NR2B-containing NMDA receptors in the dorsomedial striatum.Actin depolymerization contributes to ethanol inhibition of NMDA receptors in primary cultured cerebellar granule cells.Striatal involvement in human alcoholism and alcohol consumption, and withdrawal in animal modelsAlcohol Elicits Functional and Structural Plasticity Selectively in Dopamine D1 Receptor-Expressing Neurons of the Dorsomedial Striatum.Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogasterNew rules governing synaptic plasticity in core nucleus accumbens medium spiny neurons.Role of altered structure and function of NMDA receptors in development of alcohol dependence.Synaptic plasticity in the hippocampus shows resistance to acute ethanol exposure in transgenic mice with astrocyte-targeted enhanced CCL2 expression.Ethanol affects NMDA receptor signaling at climbing fiber-Purkinje cell synapses in mice and impairs cerebellar LTDAdaptive plasticity of NMDA receptors and dendritic spines: implications for enhanced vulnerability of the adolescent brain to alcohol addiction.Dephosphorylation of GluN2B C-terminal tyrosine residues does not contribute to acute ethanol inhibition of recombinant NMDA receptorsFyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systemsEthanol reduces neuronal excitability of lateral orbitofrontal cortex neurons via a glycine receptor dependent mechanism.Salvia miltiorrhiza Bunge Blocks Ethanol-Induced Synaptic Dysfunction through Regulation of NMDA Receptor-Dependent Synaptic Transmission.Alcohol related changes in regulation of NMDA receptor functions
P2860
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P2860
Scaffolding of Fyn kinase to the NMDA receptor determines brain region sensitivity to ethanol.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Scaffolding of Fyn kinase to t ...... region sensitivity to ethanol
@nl
Scaffolding of Fyn kinase to t ...... region sensitivity to ethanol.
@ast
Scaffolding of Fyn kinase to t ...... region sensitivity to ethanol.
@en
type
label
Scaffolding of Fyn kinase to t ...... region sensitivity to ethanol
@nl
Scaffolding of Fyn kinase to t ...... region sensitivity to ethanol.
@ast
Scaffolding of Fyn kinase to t ...... region sensitivity to ethanol.
@en
prefLabel
Scaffolding of Fyn kinase to t ...... region sensitivity to ethanol
@nl
Scaffolding of Fyn kinase to t ...... region sensitivity to ethanol.
@ast
Scaffolding of Fyn kinase to t ...... region sensitivity to ethanol.
@en
P2093
P2860
P3181
P1476
Scaffolding of Fyn kinase to t ...... region sensitivity to ethanol.
@en
P2093
Khanhky Phamluong
P2860
P304
P3181
P407
P577
2003-05-01T00:00:00Z