The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux
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The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamineRecent Advances in Understanding Amino Acid Sensing Mechanisms that Regulate mTORC1Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual ScreeningIndividual subunits of the glutamate transporter EAAC1 homotrimer function independently of each otherFunctional expression of two system A glutamine transporter isoforms in rat auditory brainstem neuronsNeutral amino acid transporter ASCT2 displays substrate-induced Na+ exchange and a substrate-gated anion conductanceCationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasitesThe Concise Guide to PHARMACOLOGY 2013/14: transporters.Association study of polymorphisms in the neutral amino acid transporter genes SLC1A4, SLC1A5 and the glycine transporter genes SLC6A5, SLC6A9 with schizophrenia.Cell-type specific mechanisms of D-serine uptake and release in the brainThe neuronal and astrocytic protein SLC38A10 transports glutamine, glutamate, and aspartate, suggesting a role in neurotransmission.Na+ interactions with the neutral amino acid transporter ASCT1.Glutamate as a neurotransmitter in the healthy brainVisualization of glutamine transporter activities in living cells using genetically encoded glutamine sensorsPromotion of both proliferation and neuronal differentiation in pluripotent P19 cells with stable overexpression of the glutamine transporter slc38a11H-NMR metabolite profiles of different strains of Plasmodium falciparum.Role of astrocytes in manganese mediated neurotoxicity.Methylmercury induces oxidative injury, alterations in permeability and glutamine transport in cultured astrocytes.Defining substrate and blocker activity of alanine-serine-cysteine transporter 2 (ASCT2) Ligands with Novel Serine AnalogsD-Serine Is a Substrate for Neutral Amino Acid Transporters ASCT1/SLC1A4 and ASCT2/SLC1A5, and Is Transported by Both Subtypes in Rat Hippocampal Astrocyte CulturesElectrogenic glutamate transporters in the CNS: molecular mechanism, pre-steady-state kinetics, and their impact on synaptic signaling.Pre-steady-state currents in neutral amino acid transporters induced by photolysis of a new caged alanine derivative.The conserved histidine 295 does not contribute to proton cotransport by the glutamate transporter EAAC1.Voltage-dependent processes in the electroneutral amino acid exchanger ASCT2Deletion of Amino Acid Transporter ASCT2 (SLC1A5) Reveals an Essential Role for Transporters SNAT1 (SLC38A1) and SNAT2 (SLC38A2) to Sustain Glutaminolysis in Cancer Cells.Manganese disrupts astrocyte glutamine transporter expression and function.Membrane transporters for the special amino acid glutamine: structure/function relationships and relevance to human health.At Least Three Transporters Likely Mediate Threonine Uptake Needed for Mouse Embryonic Stem Cell Proliferation.Inflammatory cytokine TNF-α inhibits Na(+)-glutamine cotransport in intestinal epithelial cells.Glutamine availability up-regulates expression of the amino acid transporter protein ASCT2 in HepG2 cells and stimulates the ASCT2 promoter.Identification of a plasma membrane glutamine transporter from the rat hepatoma cell line H4-IIE-C3In vivo D-serine hetero-exchange through alanine-serine-cysteine (ASC) transporters detected by microelectrode biosensors.Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism.The glycine transporter GlyT1 controls N-methyl-D-aspartic acid receptor coagonist occupancy in the mouse retina.The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells.Glutamine flux imaging using genetically encoded sensors.Molecular determinants for functional differences between alanine-serine-cysteine transporter 1 and other glutamate transporter family members.New inhibitors for the neutral amino acid transporter ASCT2 reveal its Na+-dependent anion leak.Activation of glutamate transport evokes rapid glutamine release from perisynaptic astrocytes.The heterodimeric amino acid transporter 4F2hc/LAT1 is associated in Xenopus oocytes with a non-selective cation channel that is regulated by the serine/threonine kinase sgk-1.
P2860
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P2860
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux
description
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1999
@ast
scientific journal article
@en
vedecký článok (publikovaný 1999/11/01)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/11/01)
@nl
наукова стаття, опублікована в листопаді 1999
@uk
مقالة علمية (نشرت في نوفمبر 1999)
@ar
name
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux
@ast
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux
@en
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux
@nl
type
label
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux
@ast
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux
@en
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux
@nl
prefLabel
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux
@ast
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux
@en
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux
@nl
P2093
P3181
P1476
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux
@en
P2093
C. A. Wagner
K. S. Dimmer
N. Brookes
V. Ganapathy
P304
P3181
P356
10.1046/J.1471-4159.1999.02184.X
P407
P577
1999-11-01T00:00:00Z