A three-dimensional model of the neprilysin 2 active site based on the X-ray structure of neprilysin. Identification of residues involved in substrate hydrolysis and inhibitor binding of neprilysin 2
about
The Kell protein of the common K2 phenotype is a catalytically active metalloprotease, whereas the rare Kell K1 antigen is inactive. Identification of novel substrates for the Kell proteinBioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationshipsHomology modeling and site-directed mutagenesis to identify selective inhibitors of endothelin-converting enzyme-2Amyloid-beta and Alzheimer's disease: the role of neprilysin-2 in amyloid-beta clearanceHuman neprilysin-2 (NEP2) and NEP display distinct subcellular localisations and substrate preferences.Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease?In silico based investigation of dynamic variations in neprilysin (NEP and NEP2) proteins for extracting the point of specificity.Neprilysin Inhibitors and Bradykinin
P2860
Q24298076-2FDED521-4A1E-4327-8821-D757CCD7533EQ33316208-CB6F7A96-2F68-4DDD-B245-EE0C2FE9008DQ33338181-A515A787-E3C4-489F-ACC4-676913D67CEFQ34039695-1EE8CDD8-DB52-43AE-9F87-6936A05BD164Q34785338-E3DF2316-9F01-4216-B804-26961EF848F7Q37961852-BEA17E59-44DC-442D-A11F-BB826A3C3C8EQ40022592-B468525E-53D3-4F1F-8C05-383B56F5A903Q57072764-58173F0A-C875-42C0-9BAF-D0502CDE3F99
P2860
A three-dimensional model of the neprilysin 2 active site based on the X-ray structure of neprilysin. Identification of residues involved in substrate hydrolysis and inhibitor binding of neprilysin 2
description
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2004
@ast
im Oktober 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/10/29)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/10/29)
@nl
наукова стаття, опублікована в жовтні 2004
@uk
name
A three-dimensional model of t ...... ibitor binding of neprilysin 2
@ast
A three-dimensional model of t ...... ibitor binding of neprilysin 2
@en
A three-dimensional model of t ...... ibitor binding of neprilysin 2
@nl
type
label
A three-dimensional model of t ...... ibitor binding of neprilysin 2
@ast
A three-dimensional model of t ...... ibitor binding of neprilysin 2
@en
A three-dimensional model of t ...... ibitor binding of neprilysin 2
@nl
prefLabel
A three-dimensional model of t ...... ibitor binding of neprilysin 2
@ast
A three-dimensional model of t ...... ibitor binding of neprilysin 2
@en
A three-dimensional model of t ...... ibitor binding of neprilysin 2
@nl
P2093
P2860
P356
P1476
A three-dimensional model of t ...... ibitor binding of neprilysin 2
@en
P2093
Claude Gros
Stéphanie Voisin
Tanja Ouimet
P2860
P304
46172–46181
P356
10.1074/JBC.M407333200
P407
P577
2004-10-29T00:00:00Z