Evidence that stimulation of ghrelin receptors in the spinal cord initiates propulsive activity in the colon of the rat
about
Ghrelin - a pleiotropic hormone secreted from endocrine x/a-like cells of the stomachIntrarenal ghrelin infusion stimulates distal nephron-dependent sodium reabsorption in normal rats.Preclinical evidence supporting the clinical development of central pattern generator-modulating therapies for chronic spinal cord-injured patients.Ghrelin and motilin receptor agonists: time to introduce bias into drug design.Emerging treatments in Neurogastroenterology: relamorelin: a novel gastrocolokinetic synthetic ghrelin agonist.Impact of Bioelectronic Medicine on the Neural Regulation of Pelvic Visceral Function.Surgical Intervention to Rescue Hirschsprung Disease in a Rat Model.Emerging drugs for postoperative ileus.Abnormal ghrelin secretion contributes to gastrointestinal symptoms in multiple system atrophy patients.Hypotensive effects of ghrelin receptor agonists mediated through a novel receptor.From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation.Future Treatment of Constipation-associated Disorders: Role of Relamorelin and Other Ghrelin Receptor Agonists.The prokinetic face of ghrelin.The enteric nervous system and neurogastroenterology.Ghrelin signaling in the gut, its physiological properties, and therapeutic potential.Phase II drugs under clinical investigation for the treatment of chronic constipation.Ghrelin receptors as targets for novel motility drugs.Ghrelin and motilin receptors as drug targets for gastrointestinal disorders.Ghrelin promotes nuclear factor kappa-B activation in a human B-lymphocyte cell line.New pharmacological approaches against chronic bowel and bladder problems in paralytics.Evidence that central pathways that mediate defecation utilize ghrelin receptors but do not require endogenous ghrelin.New ghrelin agonist, HM01 alleviates constipation and L-dopa-delayed gastric emptying in 6-hydroxydopamine rat model of Parkinson's diseaseColokinetic effect of noradrenaline in the spinal defecation center: implication for motility disorders.The mechanism of enhanced defecation caused by the ghrelin receptor agonist, ulimorelin.Characterization of ghrelin-sensitive neurons in the lumbosacral defecation center in rats.A ghrelin receptor agonist is an effective colokinetic in rats with diet-induced constipation.Stimulation of defecation in spinal cord-injured rats by a centrally acting ghrelin receptor agonist.Site and mechanism of the colokinetic action of the ghrelin receptor agonist, HM01.Stimulation of dopamine D2-like receptors in the lumbosacral defaecation centre causes propulsive colorectal contractions in rats.Electroacupuncture at Zusanli (ST36) ameliorates colonic neuronal nitric oxide synthase upregulation in rats with neurogenic bowel dysfunction following spinal cord injury.Intravenous ghrelin accelerates postoperative gastric emptying and time to first bowel movement in humans.Ghrelin and Motilin Control Systems in GI Physiology and Therapeutics.Colokinetic effect of somatostatin in the spinal defecation center in rats.Exogenous serotonin regulates colorectal motility via the 5-HT2 and 5-HT3 receptors in the spinal cord of rats.Neural pathways for colorectal control, relevance to spinal cord injury and treatment: a narrative review.Chronic constipation: improved understanding offers a new therapeutic approach.Identification of neurons that express ghrelin receptors in autonomic pathways originating from the spinal cord.Short-Term Effects of Relamorelin on Descending Colon Motility in Chronic Constipation: A Randomized, Controlled Trial.Local regulatory mechanism to coordinate colorectal motility in rats.
P2860
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P2860
Evidence that stimulation of ghrelin receptors in the spinal cord initiates propulsive activity in the colon of the rat
description
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Oktober 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/10/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/10/01)
@nl
наукова стаття, опублікована в жовтні 2006
@uk
مقالة علمية (نشرت في أكتوبر 2006)
@ar
name
Evidence that stimulation of g ...... tivity in the colon of the rat
@ast
Evidence that stimulation of g ...... tivity in the colon of the rat
@en
Evidence that stimulation of g ...... tivity in the colon of the rat
@nl
type
label
Evidence that stimulation of g ...... tivity in the colon of the rat
@ast
Evidence that stimulation of g ...... tivity in the colon of the rat
@en
Evidence that stimulation of g ...... tivity in the colon of the rat
@nl
prefLabel
Evidence that stimulation of g ...... tivity in the colon of the rat
@ast
Evidence that stimulation of g ...... tivity in the colon of the rat
@en
Evidence that stimulation of g ...... tivity in the colon of the rat
@nl
P2093
P2860
P1476
Evidence that stimulation of g ...... tivity in the colon of the rat
@en
P2093
Anthony D Shafton
Dorota M Ferens
Ed C Chang
Jason Witherington
Yasutake Shimizu
P2860
P304
P356
10.1113/JPHYSIOL.2006.116160
P407
P577
2006-07-27T00:00:00Z