The natural compound n-butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo
about
Neuroprotection by spice-derived nutraceuticals: you are what you eat!n-butylidenephthalide protects against dopaminergic neuron degeneration and α-synuclein accumulation in Caenorhabditis elegans models of Parkinson's diseasen-Butylidenephthalide (BP) maintains stem cell pluripotency by activating Jak2/Stat3 pathway and increases the efficiency of iPS cells generationn-Butylidenephthalide induced apoptosis in the A549 human lung adenocarcinoma cell line by coupled down-regulation of AP-2alpha and telomerase activity.Phthalide Derivatives from Angelica Sinensis Decrease Hemoglobin Oxygen Affinity: A New Allosteric-Modulating Mechanism and Potential Use as 2,3-BPG Functional SubstitutesButylidenephthalide blocks potassium channels and enhances basal tension in isolated guinea-pig trachea.Induction of apoptosis coupled to endoplasmic reticulum stress in human prostate cancer cells by n-butylidenephthalide.Crude aqueous extracts of Pluchea indica (L.) Less. inhibit proliferation and migration of cancer cells through induction of p53-dependent cell death.The Effect of Z-Ligustilide on the Mobility of Human Glioblastoma T98G CellsLocal interstitial delivery of z-butylidenephthalide by polymer wafers against malignant human gliomas.N-butylidenephthalide attenuates Alzheimer's disease-like cytopathy in Down syndrome induced pluripotent stem cell-derived neuronsBioactivities of major constituents isolated from Angelica sinensis (Danggui).Liposomal n-butylidenephthalide protects the drug from oxidation and enhances its antitumor effects in glioblastoma multiforme.Biodegradable interstitial release polymer loading a novel small molecule targeting Axl receptor tyrosine kinase and reducing brain tumour migration and invasion.Biological reactive intermediates (BRIs) formed from botanical dietary supplementsAngelica sinensis and its alkylphthalides induce the detoxification enzyme NAD(P)H: quinone oxidoreductase 1 by alkylating Keap1.The Methanol Extract of Angelica sinensis Induces Cell Apoptosis and Suppresses Tumor Growth in Human Malignant Brain TumorsCaffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells.n-Butylidenephthalide Regulated Tumor Stem Cell Genes EZH2/AXL and Reduced Its Migration and Invasion in Glioblastoma.Botanical drugs and stem cells.Cytotoxic Activities, SAR and Anti-Invasion Effects of Butylphthalide Derivatives on Human Hepatocellular Carcinoma SMMC7721 Cells.Anticancer and Antibacterial Activity Studies of Gold(I)-Alkynyl Chromones.Brain tumor senescence might be mediated by downregulation of S-phase kinase-associated protein 2 via butylidenephthalide leading to decreased cell viability.Phthalides: Distribution in Nature, Chemical Reactivity, Synthesis, and Biological Activity.Expression of Nur77 induced by an n-butylidenephthalide derivative promotes apoptosis and inhibits cell growth in oral squamous cell carcinoma.Review of Natural Product-Derived Compounds as Potent Antiglioblastoma Drugs.One-pot synthesis of 3-alkylidenephthalides from benzoic acids by a rhodium-catalyzed ortho-C-H acylation process.Potential therapeutic effects of N-butylidenephthalide from Radix Angelica Sinensis (Danggui) in human bladder cancer cells.Prevention of inflammation-mediated neurotoxicity by butylidenephthalide and its role in microglial activation.n-butylidenephthalide treatment prolongs life span and attenuates motor neuron loss in SOD1G93A mouse model of amyotrophic lateral sclerosis.Inhibitory effect of n-butylidenephthalide on neointimal hyperplasia in balloon injured rat carotid artery.Butylidenephthalide suppresses human telomerase reverse transcriptase (TERT) in human glioblastomas.Overexpression of the orphan receptor Nur77 and its translocation induced by PCH4 may inhibit malignant glioma cell growth and induce cell apoptosis.
P2860
Q24635358-E5B3E2B9-6FDE-4814-9572-779E0484147FQ27334018-0ED44BBC-F030-48BC-9D54-F4E6384EE60BQ28483641-DCFFE210-2323-4F9A-B58B-DCAB2A3F450FQ33554943-6334CD46-0963-4E48-8858-0AD3B689226CQ33906046-330B21BE-419C-4A9D-B30A-82DD0D758A82Q33994041-DD75A220-F214-4487-9865-286E8508B6F9Q34217464-ACA3E8E4-EE6B-4C94-946B-B7E6CC5DA656Q34523124-7C622C8A-C71A-42B2-BCB3-0F290494D57FQ34785447-26DC7DA8-B46E-470F-8562-6B0E25A284B8Q35021321-5BE38B93-AD3E-45E9-B76C-763B68558262Q35144310-CF24370F-3D89-480C-AAE5-5DE45100B910Q35206425-D855AC81-D666-46C9-8222-A20A00FAD4D3Q36116608-2B4A7C94-ACFB-4317-8E88-945339F57E91Q36864403-822CF659-F394-4AA6-BE92-E57588D5942EQ36996161-D56B49DD-9680-47C3-8A7C-A659EB008792Q37041881-47BCA9CE-1341-41D7-A456-6579AD500884Q37351460-A0565371-74D8-4379-9DE8-73DDB21EC1B1Q37599450-FA7C92CA-2053-4AAA-BEE6-E940E88B9D4BQ37690899-02B46066-EF23-47C8-B4ED-73B28025BB1BQ37795957-1AF6B5A3-EA15-417C-B45B-41A0A69875CFQ38819514-EEABDB80-FD80-42D4-B8D1-96992FA44BDCQ38822570-650CE504-39E9-422F-83B0-7FD91AD13072Q39030535-83929066-4E3A-45E9-AFBA-983039CDF91CQ39119157-E6D2CFE3-8DA6-4E05-9707-77C4788460D9Q39661097-A690ADEF-5046-406A-86B2-D0C3016A2D93Q44888065-4BC560B3-32FE-416F-B7FC-10317AE2C920Q45342837-33F2F893-17CC-48AC-8E9F-57CE82FC6B34Q47179934-2230F5FE-FAD1-4ED5-9C86-03887365DCFCQ48167172-0FAF8B7E-F92C-4115-95AB-E5369D7E0D4CQ48204504-126C69F2-1B92-41E1-BE6B-6D321723B748Q53263919-B6E73256-A2AC-4C14-BE09-BD4164D3CD55Q54374129-35CDDB14-B18D-4882-B800-2F66CA5E3CF2Q55463483-CDB9424A-83F8-41F9-B594-4A68BDE89DFD
P2860
The natural compound n-butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo
description
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
scientific journal article
@en
vedecký článok (publikovaný 2006/11/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/11/01)
@nl
наукова стаття, опублікована в листопаді 2006
@uk
مقالة علمية نشرت في نوفمبر 2006 حول موضوع: دماغ
@ar
name
The natural compound n-butylid ...... or growth in vitro and in vivo
@ast
The natural compound n-butylid ...... or growth in vitro and in vivo
@en
The natural compound n-butylid ...... or growth in vitro and in vivo
@nl
type
label
The natural compound n-butylid ...... or growth in vitro and in vivo
@ast
The natural compound n-butylid ...... or growth in vitro and in vivo
@en
The natural compound n-butylid ...... or growth in vitro and in vivo
@nl
prefLabel
The natural compound n-butylid ...... or growth in vitro and in vivo
@ast
The natural compound n-butylid ...... or growth in vitro and in vivo
@en
The natural compound n-butylid ...... or growth in vitro and in vivo
@nl
P2093
P2860
P1476
The natural compound n-butylid ...... or growth in vitro and in vivo
@en
P2093
Chau-Chin Lee
Horng-Jyh Harn
Nu-Man Tsai
Po-Chen Lin
Shinn-Zong Lin
Wen-Liang Chang
Yeung-Leung Cheng
Yi-Lin Chen
P2860
P304
P356
10.1111/J.1471-4159.2006.04151.X
P407
P577
2006-11-01T00:00:00Z