vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
about
Two members of an HNF1 homeoprotein family are expressed in human liverPBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1Mutations in the hepatocyte nuclear factor-1beta gene are associated with familial hypoplastic glomerulocystic kidney diseaseMore potent transcriptional activators or a transdominant inhibitor of the HNF1 homeoprotein family are generated by alternative RNA processingIdentification of a novel vertebrate homeobox gene expressed in haematopoietic cellsHNF-1beta regulates transcription of the PKD modifier gene Kif12Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberineHuman mutations affect the epigenetic/bookmarking function of HNF1BActivity of hepatocyte nuclear factor 1alpha and hepatocyte nuclear factor 1beta isoforms is differently affected by the inhibition of protein phosphatases 1/2ALFB1/HNF1 acts as a repressor of its own transcriptionHNF1β is essential for nephron segmentation during nephrogenesisStructure of the gene encoding hepatocyte nuclear factor 1 (HNF1)Hepatocyte nuclear factor 1 alpha is expressed in a hamster insulinoma line and transactivates the rat insulin I geneThyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1.Hepatocyte nuclear factor 1 is essential for transcription of sodium-dependent vitamin C transporter protein 1Liver enriched transcription factors and differentiation of hepatocellular carcinomaHepatocyte nuclear factor 1 and hypertensive nephropathy.Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line.Definition and prediction of the full range of transcription factor binding sites--the hepatocyte nuclear factor 1 dimeric siteRegulation of albumin gene expression in hepatoma cells of fetal phenotype: dominant inhibition of HNF1 function and role of ubiquitous transcription factorsCrystallization of hepatocyte nuclear factor 1beta in complex with DNA.Cloning and sequencing of PYBP, a pyrimidine-rich specific single strand DNA-binding protein.Overexpression of pterin-4a-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 in human colon cancer.Expression profiling in ovarian clear cell carcinoma: identification of hepatocyte nuclear factor-1 beta as a molecular marker and a possible molecular target for therapy of ovarian clear cell carcinomaHepatocyte Nuclear Factor-1β Induces Redifferentiation of Dedifferentiated Tubular Epithelial Cells.Liver-specific expression of human insulin-like growth factor binding protein 1: functional role of transcription factor HNF1 in vivo.HNF4 and HNF1 as well as a panel of hepatic functions are extinguished and reexpressed in parallel in chromosomally reduced rat hepatoma-human fibroblast hybridsIdentification of a bipotential precursor cell in hepatic cell lines derived from transgenic mice expressing cyto-Met in the liverHepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells.Overproduction of a truncated hepatocyte nuclear factor 3 protein inhibits expression of liver-specific genes in hepatoma cells.Positive regulation of the vHNF1 promoter by the orphan receptors COUP-TF1/Ear3 and COUP-TFII/Arp1.Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus.The activity of the highly inducible mouse phenylalanine hydroxylase gene promoter is dependent upon a tissue-specific, hormone-inducible enhancerHepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cellsHepatocyte nuclear factor 1alpha gene inactivation impairs chromatin remodeling and demethylation of the phenylalanine hydroxylase geneEpigenetic inactivation of TCF2 in ovarian cancer and various cancer cell lines.Developmental regulation and tissue distribution of the liver transcription factor LFB1 (HNF1) in Xenopus laevis.Early Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia.Hepatocyte nuclear factor 1 coordinates multiple processes in a model of intestinal epithelial cell function.Promoter-specific transactivation of hepatitis B virus transcription by a glutamine- and proline-rich domain of hepatocyte nuclear factor 1.
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P2860
vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
description
1991 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1991
@ast
im Juni 1991 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1991/06/01)
@sk
vědecký článek publikovaný v roce 1991
@cs
wetenschappelijk artikel (gepubliceerd op 1991/06/01)
@nl
наукова стаття, опублікована в червні 1991
@uk
مقالة علمية (نشرت في يونيو 1991)
@ar
name
vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
@ast
vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
@en
vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
@nl
type
label
vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
@ast
vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
@en
vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
@nl
prefLabel
vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
@ast
vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
@en
vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
@nl
P2093
P2860
P3181
P1433
P1476
vHNF1 is a homeoprotein that activates transcription and forms heterodimers with HNF1
@en
P2093
Cereghini S
Rey-Campos J
P2860
P304
P3181
P356
10.1002/J.1460-2075.1991.TB07665.X
P407
P577
1991-06-01T00:00:00Z