DHCR24 gene knockout mice demonstrate lethal dermopathy with differentiation and maturation defects in the epidermis
about
Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatinHidden disease susceptibility and sexual dimorphism in the heterozygous knockout of Cyp51 from cholesterol synthesisBile acids down-regulate caveolin-1 in esophageal epithelial cells through sterol responsive element-binding proteinA detailed genome-wide reconstruction of mouse metabolism based on human Recon 1.Regulation of ABCG1 expression in human keratinocytes and murine epidermis.Hair and skin sterols in normal mice and those with deficient dehydrosterol reductase (DHCR7), the enzyme associated with Smith-Lemli-Opitz syndromeMalformation syndromes caused by disorders of cholesterol synthesis.Disruption of the gene encoding 3beta-hydroxysterol Delta-reductase (Tm7sf2) in mice does not impair cholesterol biosynthesis.Thematic review series: skin lipids. The role of epidermal lipids in cutaneous permeability barrier homeostasis.Aquaporin-3 in keratinocytes and skin: its role and interaction with phospholipase D2.Epidermal expression of an Elovl4 transgene rescues neonatal lethality of homozygous Stargardt disease-3 mice.The role of fatty acid desaturases in epidermal metabolismThe desmosterolosis phenotype: spasticity, microcephaly and micrognathia with agenesis of corpus callosum and loss of white matter.Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndromeCytoplasmic ezrin and moesin correlate with poor survival in head and neck squamous cell carcinomaDefects of cholesterol biosynthesis.Abnormal barrier function in the pathogenesis of ichthyosis: therapeutic implications for lipid metabolic disorders.Estrogen receptor-mediated neuroprotection: The role of the Alzheimer's disease-related gene seladin-1The outer frontier: the importance of lipid metabolism in the skinSkin-specific deletion of stearoyl-CoA desaturase-1 alters skin lipid composition and protects mice from high fat diet-induced obesity.Developmental expression pattern of the cholesterogenic enzyme NSDHL and negative selection of NSDHL-deficient cells in the heterozygous Bpa(1H)/+ mouse.Defects in cholesterol synthesis genes in mouse and in humans: lessons for drug development and safer treatments.Disorders of sterol synthesis: beyond Smith-Lemli-Opitz syndrome.Neuroprotective effects of estrogens: the role of cholesterol.3β-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species.Cholesterol substitution increases the structural heterogeneity of caveolae.Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells.Desmosterolosis: an illustration of diagnostic ambiguity of cholesterol synthesis disorders.Pathogenesis of the cutaneous phenotype in inherited disorders of cholesterol metabolism: Therapeutic implications for topical treatment of these disorders.Embryotoxicant-specific transcriptomic responses in rat postimplantation whole-embryo culture.Increased expression of aquaporin-3 in the epidermis of DHCR24 knockout mice.Desmosterolosis presenting with multiple congenital anomalies.Cytosolic StAR-related lipid transfer domain 4 (STARD4) protein influences keratinocyte lipid phenotype and differentiation status.Desmosterolosis-phenotypic and molecular characterization of a third case and review of the literature.
P2860
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P2860
DHCR24 gene knockout mice demonstrate lethal dermopathy with differentiation and maturation defects in the epidermis
description
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im März 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/03/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/03/01)
@nl
наукова стаття, опублікована в березні 2006
@uk
مقالة علمية (نشرت في مارس 2006)
@ar
name
DHCR24 gene knockout mice demo ...... ation defects in the epidermis
@ast
DHCR24 gene knockout mice demo ...... ation defects in the epidermis
@en
DHCR24 gene knockout mice demo ...... ation defects in the epidermis
@nl
type
label
DHCR24 gene knockout mice demo ...... ation defects in the epidermis
@ast
DHCR24 gene knockout mice demo ...... ation defects in the epidermis
@en
DHCR24 gene knockout mice demo ...... ation defects in the epidermis
@nl
prefLabel
DHCR24 gene knockout mice demo ...... ation defects in the epidermis
@ast
DHCR24 gene knockout mice demo ...... ation defects in the epidermis
@en
DHCR24 gene knockout mice demo ...... ation defects in the epidermis
@nl
P2093
P356
P1476
DHCR24 gene knockout mice demo ...... ation defects in the epidermis
@en
P2093
David Zadworny
Fukushi Kambe
Kazuko Maki
Kohji Murakami
Michiyo Yamamoto
Rusella Mirza
Sachiko Ohmori
Shizu Hayasaka
Takahide Kaji
P2888
P304
P356
10.1038/SJ.JID.5700111
P407
P577
2006-03-01T00:00:00Z
P5875
P6179
1009352102