Loss of Tbx4 blocks hindlimb development and affects vascularization and fusion of the allantois
about
Lateral motor column axons execute a ternary trajectory choice between limb and body tissuesMutations in the human TBX4 gene cause small patella syndrome.The enigmatic primitive streak: prevailing notions and challenges concerning the body axis of mammalsThe evolutionary history of the development of the pelvic fin/hindlimbThe T-box gene family: emerging roles in development, stem cells and cancerMechanisms of retinoic acid signalling and its roles in organ and limb developmentCooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heartPitx1 is necessary for normal initiation of hindlimb outgrowth through regulation of Tbx4 expression and shapes hindlimb morphologies via targeted growth controlDefects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65HOXA13 Is essential for placental vascular patterning and labyrinth endothelial specificationMOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndromeShape Ontogeny of the Distal Femur in the Hominidae with Implications for the Evolution of BipedalityShared Enhancer Activity in the Limbs and Phallus and Functional Divergence of a Limb-Genital cis-Regulatory Element in SnakesA relative shift in cloacal location repositions external genitalia in amniote evolutionThe genome of the Gulf pipefish enables understanding of evolutionary innovationsLMP4 regulates Tbx5 protein subcellular localization and activity.Oriented cell motility and division underlie early limb bud morphogenesis.Tbx4/5 gene duplication and the origin of vertebrate paired appendages.Analysis of homeobox gene action may reveal novel angiogenic pathways in normal placental vasculature and in clinical pregnancy disorders associated with abnormal placental angiogenesisPitx2-dependent occupancy by histone deacetylases is associated with T-box gene regulation in mammalian abdominal tissue.Investigating the role of tbx4 in the female germline in mice.Hedgehog signaling in the posterior region of the mouse gastrula suggests manifold roles in the fetal-umbilical connection and posterior morphogenesis.Tbx4 and tbx5 acting in connective tissue are required for limb muscle and tendon patterningThe microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning.Identity and fate of Tbx4-expressing cells reveal developmental cell fate decisions in the allantois, limb, and external genitaliaTBX4 mutations (small patella syndrome) are associated with childhood-onset pulmonary arterial hypertensionMultiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system.Candidate gene approach identifies multiple genes and signaling pathways downstream of Tbx4 in the developing allantois.RA Acts in a Coherent Feed-Forward Mechanism with Tbx5 to Control Limb Bud Induction and Initiation.Tbx4 interacts with the short stature homeobox gene Shox2 in limb development.Mesothelium of the murine allantois exhibits distinct regional properties.A combination of activation and repression by a colinear Hox code controls forelimb-restricted expression of Tbx5 and reveals Hox protein specificity.Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice.Low expression of TBX4 predicts poor prognosis in patients with stage II pancreatic ductal adenocarcinoma.Transcriptional dynamics of homeobox C11 gene in water buffalo bubalus bubalis.Recruitment of 5' Hoxa genes in the allantois is essential for proper extra-embryonic function in placental mammalsThe ulnar-mammary syndrome gene, Tbx3, is a direct target of the retinoic acid signaling pathway, which regulates its expression during mouse limb developmentProbable second fetus with Marles-Chudley syndrome: cardiac calcifications with ulnar deficiency and absent/hypoplastic thumbs.Hox genes regulate the onset of Tbx5 expression in the forelimb.Heads, Shoulders, Elbows, Knees, and Toes: Modular Gdf5 Enhancers Control Different Joints in the Vertebrate Skeleton
P2860
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P2860
Loss of Tbx4 blocks hindlimb development and affects vascularization and fusion of the allantois
description
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Juni 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/06/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/06/01)
@nl
наукова стаття, опублікована в червні 2003
@uk
مقالة علمية (نشرت في يونيو 2003)
@ar
name
Loss of Tbx4 blocks hindlimb d ...... on and fusion of the allantois
@ast
Loss of Tbx4 blocks hindlimb d ...... on and fusion of the allantois
@en
Loss of Tbx4 blocks hindlimb d ...... on and fusion of the allantois
@nl
type
label
Loss of Tbx4 blocks hindlimb d ...... on and fusion of the allantois
@ast
Loss of Tbx4 blocks hindlimb d ...... on and fusion of the allantois
@en
Loss of Tbx4 blocks hindlimb d ...... on and fusion of the allantois
@nl
prefLabel
Loss of Tbx4 blocks hindlimb d ...... on and fusion of the allantois
@ast
Loss of Tbx4 blocks hindlimb d ...... on and fusion of the allantois
@en
Loss of Tbx4 blocks hindlimb d ...... on and fusion of the allantois
@nl
P356
P1433
P1476
Loss of Tbx4 blocks hindlimb d ...... on and fusion of the allantois
@en
P2093
L. A. Naiche
Virginia E. Papaioannou
P304
P356
10.1242/DEV.00504
P407
P577
2003-06-01T00:00:00Z