The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules
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A role for MHC class II antigen processing in B cell development.Roles for major histocompatibility complex glycosylation in immune functionAchieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expressionMacrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complexA novel approach to identify antigens recognized by CD4 T cells using complement-opsonized bacteria expressing a cDNA library.Class II transactivator (CIITA) enhances cytoplasmic processing of HIV-1 Pr55Gag.Helicobacter pylori binds to CD74 on gastric epithelial cells and stimulates interleukin-8 productionIntracellular transport and peptide loading of MHC class II molecules: regulation by chaperones and motors.Proteolysis of major histocompatibility complex class II-associated invariant chain is regulated by the alternatively spliced gene product, p41.Invariant chain induces B cell maturation in a process that is independent of its chaperonic activity.Expression of endogenous peptide-major histocompatibility complex class II complexes derived from invariant chain-antigen fusion proteinsInflammatory dendritic cells--not basophils--are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergenPromiscuous binding of invariant chain-derived CLIP peptide to distinct HLA-I molecules revealed in leukemic cells.The Helicobacter pylori urease B subunit binds to CD74 on gastric epithelial cells and induces NF-kappaB activation and interleukin-8 production.HLA-DP, HLA-DQ, and HLA-DR have different requirements for invariant chain and HLA-DM.Altered positive selection due to corecognition of floppy peptide/MHC II conformers supports an integrative model of thymic selection.Uncovering the role of invariant chain in controlling MHC class II antigen capture.To B or not to B: role of B cells in pathogenesis of arthritis in HLA transgenic mice.CD74 deficiency ameliorates Pseudomonas aeruginosa-induced ocular infection.The cytokine midkine and its receptor RPTPĪ¶ regulate B cell survival in a pathway induced by CD74.Dendritic cell maturation and antigen presentation in the absence of invariant chain.Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulum.Assembly and peptide binding of major histocompatibility complex class II heterodimers in an in vitro translation system.Quantitating MHC class II trafficking in primary dendritic cells using imaging flow cytometryRestrictive clonal allocation in the chimeric mouse brainMajor histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity.The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancyBinding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.T cell recognition of major histocompatibility complex class II complexes with invariant chain processing intermediates.Inhibition of invariant chain (Ii)-calnexin interaction results in enhanced degradation of Ii but does not prevent the assembly of alpha beta Ii complexesEvidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CLInvariant chain controls H2-M proteolysis in mouse splenocytes and dendritic cellsThe formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli.T helper subset differentiation in the absence of invariant chainAntagonist peptide selects thymocytes expressing a class II major histocompatibility complex-restricted T cell receptor into the CD8 lineageTransporters associated with antigen processing (TAP)-independent presentation of soluble insulin to alpha/beta T cells by the class Ib gene product, Qa-1(b).Functionality of major histocompatibility complex class II molecules in mice doubly deficient for invariant chain and H-2M complexesMHC Class II Protein Turnover In vivo and Its Relevance for Autoimmunity in Non-Obese Diabetic Mice.How MHC class II molecules reach the endocytic pathway.Biosynthesis of major histocompatibility complex molecules and generation of T cells in Ii TAP1 double-mutant mice.
P2860
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P2860
The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules
description
1994 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« ÕÕ„ÕæÖÕøÖÕ”ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
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@hyw
1994 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« ÖÕ„ÕæÖÕ¾Õ”ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
artĆculu cientĆficu espublizĆ”u en 1994
@ast
im Februar 1994 verƶffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedeckĆ½ ÄlĆ”nok (publikovanĆ½ 1994/02/01)
@sk
vÄdeckĆ½ ÄlĆ”nek publikovanĆ½ v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/02/01)
@nl
Š½Š°ŃŠŗŠ¾Š²Š° ŃŃŠ°ŃŃŃ, Š¾ŠæŃŠ±Š»ŃŠŗŠ¾Š²Š°Š½Š° Š² Š»ŃŃŠ¾Š¼Ń 1994
@uk
Ł
ŁŲ§ŁŲ© Ų¹ŁŁ
ŁŲ© (ŁŲ“Ų±ŲŖ ŁŁ ŁŲØŲ±Ų§ŁŲ± 1994)
@ar
name
The invariant chain is require ...... ity complex class II molecules
@ast
The invariant chain is require ...... ity complex class II molecules
@en
The invariant chain is require ...... ity complex class II molecules
@nl
type
label
The invariant chain is require ...... ity complex class II molecules
@ast
The invariant chain is require ...... ity complex class II molecules
@en
The invariant chain is require ...... ity complex class II molecules
@nl
prefLabel
The invariant chain is require ...... ity complex class II molecules
@ast
The invariant chain is require ...... ity complex class II molecules
@en
The invariant chain is require ...... ity complex class II molecules
@nl
P2093
P2860
P356
P1476
The invariant chain is require ...... ity complex class II molecules
@en
P2093
E. A. Elliott
I. Mellman
J. Elsemore
J. R. Drake
P. Webster
R. A. Flavell
S. Amigorena
P2860
P304
P356
10.1084/JEM.179.2.681
P407
P577
1994-02-01T00:00:00Z