The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif
about
HLA-DO is a lysosomal resident which requires association with HLA-DM for efficient intracellular transportAP-3: an adaptor-like protein complex with ubiquitous expression.Endocytic clathrin-coated pit formation is independent of receptor internalization signal levelsHuman leukocyte Antigen-DM polymorphisms in autoimmune diseasesIn vivo characterization of the proteasome regulator PA28Editing of the HLA-DR-peptide repertoire by HLA-DMDecreased endosomal delivery of major histocompatibility complex class II-invariant chain complexes in dynamin-deficient cellsThe impact of the non-classical MHC proteins HLA-DM and HLA-DO on loading of MHC class II moleculesCLIP-derived self peptides bound to MHC class II molecules of medullary thymic epithelial cells differ from those of cortical thymic epithelial cells in their diversity, length, and C-terminal processing.Comprehensive analysis of MHC class II genes in teleost fish genomes reveals dispensability of the peptide-loading DM system in a large part of vertebrates.Pathways of antigen processing.A point mutation in the groove of HLA-DO allows egress from the endoplasmic reticulum independent of HLA-DM.Coevolution of TCR-MHC interactions: conserved MHC tertiary structure is not sufficient for interactions with the TCR.Intracellular traffic to compartments for MHC class II peptide loading: signals for endosomal and polarized sorting.Intracellular transport and peptide loading of MHC class II molecules: regulation by chaperones and motors.The role of H2-O and HLA-DO in major histocompatibility complex class II-restricted antigen processing and presentation.H2-O, a MHC class II-like protein, sets a threshold for B-cell entry into germinal centers.Functional HLA-DM on the surface of B cells and immature dendritic cells.H2-DMalpha(-/-) mice show the importance of major histocompatibility complex-bound peptide in cardiac allograft rejectionProtein targeting by tyrosine- and di-leucine-based signals: evidence for distinct saturable componentsA dominant-negative clathrin mutant differentially affects trafficking of molecules with distinct sorting motifs in the class II major histocompatibility complex (MHC) pathwayRight place, right time, right peptide: DO keeps DM focused.Invariant chain controls H2-M proteolysis in mouse splenocytes and dendritic cellsHLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR moleculesInteraction between HLA-DM and HLA-DR involves regions that undergo conformational changes at lysosomal pH.HLA-DO and Its Role in MHC Class II Antigen Presentation.Multiple signals regulate the intracellular trafficking of HLA-DM in B-lymphoblastoid cells.A role for HLA-DO as a co-chaperone of HLA-DM in peptide loading of MHC class II molecules.The endogenous pathway of MHC class II antigen presentation.Protein folding coupled to disulphide bond formation.Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells.Functional analysis of tryptophans alpha 62 and beta 120 on HLA-DM.A cytosolic pathway for MHC class II-restricted antigen processing that is proteasome and TAP dependent.
P2860
Q24315931-243B98DD-4827-4F20-96E4-4689E98AB0A1Q24315945-5FA312E1-75E7-48F3-A2F1-6A5788938F21Q24651514-02C8F541-D0E6-4072-B2D4-DD6A9398D3FCQ26741035-7A14F3DB-AE61-4C76-B98F-C59FA8CC70E2Q28282216-8A40ACC2-D7D9-47A9-BFF6-0E40A4813CB5Q28613148-7DEDAA74-36FB-4D18-9997-F003F51F0B3AQ28613183-9D3D8DE3-E491-4390-8316-05FCD1A88019Q29037067-B067B75D-E363-4D12-997F-2B67C149FD8EQ30651730-CF4A2419-C795-4233-B222-7A41B7B7F96AQ31144496-248C1557-90DB-420C-932F-35BDEB951F9BQ33631854-8B080E01-7493-4C24-ACB6-296979D82009Q33772095-A3DD9BA1-EC80-48FB-966B-7FC50E6B6393Q33780788-7D2A3060-E6C1-43D7-9E28-4FC1DA75A2B3Q33815419-17E39ABA-2F93-4669-A2C2-BA8EB88B212AQ33815425-189F86EC-7579-4C1C-966B-3EA1611DB67AQ33815445-8DC439D0-487B-40B5-BF91-27404E55AA74Q34151755-43AA12A3-0C7A-4703-8BC3-047673010BA4Q34667803-BBC27563-5E5F-4A7D-95AE-83F7FEE8DDAFQ35834673-11A224BE-92E7-42CC-8A8E-D36B3DE08242Q36237576-DA726DFF-916C-4BDF-8BCF-C9382F9FFC39Q36255192-A5AB7ED6-EE94-4B16-9F99-3C113CD3508AQ36266508-DFB1BC29-746A-4DE9-8DC2-92ED6C88DAA4Q36368351-17091392-534E-4975-9FE7-57AE0640D745Q36377428-F2298391-5ED2-4178-941B-D10E8F68F3AAQ36720788-FCBE349D-82D8-4960-9882-C102A33D40B3Q38134729-B9E321AD-9296-43E5-BC1F-0CF05B394E57Q41026652-0E1BE1D4-F880-4337-8088-88FB75F68F49Q41030957-C1A2D0F8-9067-4E04-B214-970415065022Q41168212-2B00832D-256D-42EA-82D6-6A7090F25AAAQ41648380-BE4125AB-5651-43A9-A017-2E1B043C6214Q42132231-D3EF2082-6062-4998-926A-D293F3FB8CDDQ43802418-EEC037C8-911E-41AD-9E39-D31DA7ECD7B2Q44791801-ECC0DC91-E5C5-46AE-A0F4-55A39E48403E
P2860
The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif
description
1995 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1995
@ast
scientific journal article
@en
vedecký článok (publikovaný 1995/11/01)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/11/01)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в листопаді 1995
@uk
مقالة علمية (نشرت في نوفمبر 1995)
@ar
name
The MHC class II molecule H2-M ...... tyrosine-based targeting motif
@ast
The MHC class II molecule H2-M ...... tyrosine-based targeting motif
@en
The MHC class II molecule H2-M ...... tyrosine-based targeting motif
@nl
type
label
The MHC class II molecule H2-M ...... tyrosine-based targeting motif
@ast
The MHC class II molecule H2-M ...... tyrosine-based targeting motif
@en
The MHC class II molecule H2-M ...... tyrosine-based targeting motif
@nl
prefLabel
The MHC class II molecule H2-M ...... tyrosine-based targeting motif
@ast
The MHC class II molecule H2-M ...... tyrosine-based targeting motif
@en
The MHC class II molecule H2-M ...... tyrosine-based targeting motif
@nl
P2093
P3181
P1433
P1476
The MHC class II molecule H2-M ...... tyrosine-based targeting motif
@en
P2093
A. Péléraux
L. Karlsson
M. Liljedahl
P. A. Peterson
R. Lindstedt
P304
P3181
P356
10.1016/1074-7613(95)90127-2
P407
P577
1995-11-01T00:00:00Z