Expression and function of orphan nuclear receptor TLX in adult neural stem cells
about
ZNF536, a novel zinc finger protein specifically expressed in the brain, negatively regulates neuron differentiation by repressing retinoic acid-induced gene transcriptionHistone deacetylase-associating Atrophin proteins are nuclear receptor corepressorsOrphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferationSignaling mechanisms regulating adult neural stem cells and neurogenesisA feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determinationThe nuclear receptor tailless is required for neurogenesis in the adult subventricular zoneOrphan nuclear receptors in drug discoveryHmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf ExpressionMutation and evolutionary analyses identify NR2E1-candidate-regulatory mutations in humans with severe cortical malformationsAdult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cellsIn vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampusMolecular Mechanism of Adult Neurogenesis and its Association with Human Brain DiseasesRegeneration strategies after the adult mammalian central nervous system injury-biomaterialsLipid-sensors, enigmatic-orphan and orphan nuclear receptors as therapeutic targets in breast-cancerMolecular Biomarkers for Embryonic and Adult Neural Stem Cell and NeurogenesisNuclear receptors and AMPK: resetting metabolismTLX: A master regulator for neural stem cell maintenance and neurogenesisSox2 transcription network acts as a molecular switch to regulate properties of neural stem cellsRole of Nuclear Receptors in Central Nervous System Development and Associated DiseasesmiR-9 and TLX: chasing tails in neural stem cellsThe protective effect of melatonin on neural stem cell against LPS-induced inflammationThe oncoprotein BCL11A binds to orphan nuclear receptor TLX and potentiates its transrepressive functionNuclear receptor TLX regulates cell cycle progression in neural stem cells of the developing brainThe T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zoneThe human orphan nuclear receptor tailless (TLX, NR2E1) is druggableNuclear receptor co-repressor is required to maintain proliferation of normal intestinal epithelial cells in culture and down-modulates the expression of pigment epithelium-derived factorEpigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cellsUnlocking mechanisms in interleukin-1β-induced changes in hippocampal neurogenesis--a role for GSK-3β and TLXTlx acts as a proangiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytesArs2 maintains neural stem-cell identity through direct transcriptional activation of Sox2Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1Histone demethylase LSD1 regulates neural stem cell proliferationGenome-wide analysis of N1ICD/RBPJ targets in vivo reveals direct transcriptional regulation of Wnt, SHH, and hippo pathway effectors by Notch1The Tlx gene regulates the timing of neurogenesis in the cortexThe photoreceptor-specific nuclear receptor Nr2e3 interacts with Crx and exerts opposing effects on the transcription of rod versus cone genesThe nuclear receptor TLX is required for gliomagenesis within the adult neurogenic niche.Hyperactivity, startle reactivity and cell-proliferation deficits are resistant to chronic lithium treatment in adult Nr2e1(frc/frc) miceThe C. elegans Tailless/TLX transcription factor nhr-67 controls neuronal identity and left/right asymmetric fate diversificationSpecificity of DNA-binding by the FAX-1 and NHR-67 nuclear receptors of Caenorhabditis elegans is partially mediated via a subclass-specific P-box residue.Cell lineage and regional identity of cultured spinal cord neural stem cells and comparison to brain-derived neural stem cells.
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Expression and function of orphan nuclear receptor TLX in adult neural stem cells
description
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2004
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scientific journal article
@en
vedecký článok (publikovaný 2004/01/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/01/01)
@nl
наукова стаття, опублікована в січні 2004
@uk
مقالة علمية (نشرت عام 2004)
@ar
name
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
@ast
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
@en
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
@nl
type
label
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
@ast
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
@en
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
@nl
prefLabel
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
@ast
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
@en
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
@nl
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P1476
Expression and function of orphan nuclear receptor TLX in adult neural stem cells
@en
P2093
D. Chichung Lie
Fred H. Gage
Jasodhara Ray
Kinichi Nakashima
Philippe Taupin
Ruth T. Yu
Yanhong Shi
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P2888
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P356
10.1038/NATURE02211
P407
P577
2004-01-01T00:00:00Z
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P6179
1011173926