Organ-specific increase in mutation accumulation and apoptosis rate in CuZn-superoxide dismutase-deficient mice
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Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humansBeyond Diabetes: Does Obesity-Induced Oxidative Stress Drive the Aging Process?Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsElevated oxidative stress in erythrocytes due to a SOD1 deficiency causes anaemia and triggers autoantibody productionEffect of Ku80 deficiency on mutation frequencies and spectra at a LacZ reporter locus in mouse tissues and cellsDeletion of p66Shc in mice increases the frequency of size-change mutations in the lacZ transgeneCatalytic antioxidants and neurodegenerationEvolution of a higher intracellular oxidizing environment in Caenorhabditis elegans under relaxed selection.No evidence of elevated germline mutation accumulation under oxidative stress in Caenorhabditis elegans.Genome dynamics and transcriptional deregulation in aging.The superoxide dismutase 1 3'UTR maintains high expression of the SOD1 gene in cancer cells: The involvement of the RNA-binding protein AUF-1.Superoxide dismutase 1 (SOD1) is essential for H2O2-mediated oxidation and inactivation of phosphatases in growth factor signaling.Dietary restriction attenuates the accelerated aging phenotype of Sod1(-/-) miceEffect of Ames dwarfism and caloric restriction on spontaneous DNA mutation frequency in different mouse tissuesDNA double-strand breaks: a potential causative factor for mammalian aging?Redox regulation of cell survivalDeletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repairChronological aging in Saccharomyces cerevisiae.Aging, nutrient signaling, hematopoietic senescence, and cancer.Revisiting an age-old question regarding oxidative stress.Unraveling new functions of superoxide dismutase using yeast model system: Beyond its conventional role in superoxide radical scavenging.Keeping up with the Red Queen: the pace of aging as an adaptation.A new role for oxidative stress in aging: The accelerated aging phenotype in Sod1-/- mice is correlated to increased cellular senescenceSOD1 Is Essential for the Viability of DT40 Cells and Nuclear SOD1 Functions as a Guardian of Genomic DNAAccumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells.Late-onset increases in oxidative stress and other tumorigenic activities and tumors with a Ha-ras mutation in the liver of adult male C3H mice gestationally exposed to arsenic.Putative proto-oncogene Pir expression is significantly up-regulated in the spleen and kidney of cytosolic superoxide dismutase-deficient mice.Oxidative stress caused by a SOD1 deficiency ameliorates thioacetamide-triggered cell death via CYP2E1 inhibition but stimulates liver steatosis.Inactivation of RAD52 and HDF1 DNA repair genes leads to premature chronological aging and cellular instability.Alterations in the expression of genes related to NF-κB signaling in liver and kidney of CuZnSOD-deficient mice.
P2860
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P2860
Organ-specific increase in mutation accumulation and apoptosis rate in CuZn-superoxide dismutase-deficient mice
description
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Dezember 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/12/15)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/12/15)
@nl
наукова стаття, опублікована в грудні 2005
@uk
مقالة علمية (نشرت في 15-12-2005)
@ar
name
Organ-specific increase in mut ...... oxide dismutase-deficient mice
@ast
Organ-specific increase in mut ...... oxide dismutase-deficient mice
@en
Organ-specific increase in mut ...... oxide dismutase-deficient mice
@nl
type
label
Organ-specific increase in mut ...... oxide dismutase-deficient mice
@ast
Organ-specific increase in mut ...... oxide dismutase-deficient mice
@en
Organ-specific increase in mut ...... oxide dismutase-deficient mice
@nl
prefLabel
Organ-specific increase in mut ...... oxide dismutase-deficient mice
@ast
Organ-specific increase in mut ...... oxide dismutase-deficient mice
@en
Organ-specific increase in mut ...... oxide dismutase-deficient mice
@nl
P2093
P3181
P1433
P1476
Organ-specific increase in mut ...... oxide dismutase-deficient mice
@en
P2093
Ana Maria Garcia
Armando Rodriguez
Carlos Cabrera
Rita A. Busuttil
Ting-Ting Huang
Woo Ho Kim
Yousin Suh
P304
11271–11275
P3181
P356
10.1158/0008-5472.CAN-05-2980
P407
P577
2005-12-15T00:00:00Z