Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon
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Restless Legs Syndrome: Current Concepts about Disease PathophysiologyGenomic Views of Transcriptional Enhancers: Essential Determinants of Cellular Identity and Activity-Dependent Responses in the CNSNuclear organization and 3D chromatin architecture in cognition and neuropsychiatric disordersMEIS1 variant as a determinant of autonomic imbalance in Restless Legs Syndrome.Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation.Mechanisms of iron metabolism in Caenorhabditis elegansBlood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome.Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traitsTargeted resequencing and systematic in vivo functional testing identifies rare variants in MEIS1 as significant contributors to restless legs syndrome.Enhancer variants: evaluating functions in common disease.Path from schizophrenia genomics to biology: gene regulation and perturbation in neurons derived from induced pluripotent stem cells and genome editing.Non-coding genetic variants in human disease.Common variation in atrial fibrillation: navigating the path from genetic association to mechanism.Sensitive detection of chromatin-altering polymorphisms reveals autoimmune disease mechanisms.Animal models of RLS phenotypes.Modeling disease risk through analysis of physical interactions between genetic variants within chromatin regulatory circuitry.Meis1: effects on motor phenotypes and the sensorimotor system in miceTopologically associating domains are ancient features that coincide with Metazoan clusters of extreme noncoding conservation.Intragenic CpG islands play important roles in bivalent chromatin assembly of developmental genesTwo new targeted alleles for the comprehensive analysis of Meis1 functions in the mouse.Association of Restless Legs Syndrome With Incident Parkinson's Disease.Conserved non-coding elements: developmental gene regulation meets genome organization.Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis.Sleep disturbance by pramipexole is modified by Meis1 in mice.A screen for deeply conserved non-coding GWAS SNPs uncovers a MIR-9-2 functional mutation associated to retinal vasculature defects in human.Lack of Association Between Shape and Volume of Subcortical Brain Structures and Restless Legs Syndrome.Differential Dopamine D1 and D3 Receptor Modulation and Expression in the Spinal Cord of Two Mouse Models of Restless Legs Syndrome
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P2860
Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon
description
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2014
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im April 2014 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2014/04/01)
@sk
vědecký článek publikovaný v roce 2014
@cs
wetenschappelijk artikel (gepubliceerd op 2014/04/01)
@nl
наукова стаття, опублікована у квітні 2014
@uk
مقالة علمية (نشرت في أبريل 2014)
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name
Restless legs syndrome-associa ...... n the developing telencephalon
@ast
Restless legs syndrome-associa ...... n the developing telencephalon
@en
Restless legs syndrome-associa ...... n the developing telencephalon
@nl
type
label
Restless legs syndrome-associa ...... n the developing telencephalon
@ast
Restless legs syndrome-associa ...... n the developing telencephalon
@en
Restless legs syndrome-associa ...... n the developing telencephalon
@nl
prefLabel
Restless legs syndrome-associa ...... n the developing telencephalon
@ast
Restless legs syndrome-associa ...... n the developing telencephalon
@en
Restless legs syndrome-associa ...... n the developing telencephalon
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Restless legs syndrome-associa ...... n the developing telencephalon
@en
P2093
Derek Spieler
Erik Tilch
Franziska Knauf
Heekyoung Lee
Helmut Fuchs
Maria Kaffe
Melina Claussnitzer
Nazanin Karbalai
Ronald Naumann
Stefanie M. Hauck
P2860
P304
P3181
P356
10.1101/GR.166751.113
P50
P577
2014-04-01T00:00:00Z