Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
about
Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1Molecular functions of the TLE tetramerization domain in Wnt target gene repressionCovalent histone modifications--miswritten, misinterpreted and mis-erased in human cancersAn intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acidMammary Development and Breast Cancer: A Wnt PerspectivePost-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virusThe many faces and functions of β-cateninPositional variations in mammary gland development and cancerAllosteric Remodelling of the Histone H3 Binding Pocket in the Pygo2 PHD Finger Triggered by Its Binding to the B9L/BCL9 Co-FactorEvolutionary Adaptation of the Fly Pygo PHD Finger toward Recognizing Histone H3 Tail Methylated at Arginine 2Mammary morphogenesis and regeneration require the inhibition of EMT at terminal end buds by Ovol2 transcriptional repressorThe WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineageCytokeratin expression during mouse embryonic and early postnatal mammary gland developmentKDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/β-catenin signalling.lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs.Coop functions as a corepressor of Pangolin and antagonizes Wingless signalingMolecular mechanisms guiding embryonic mammary gland development.High-resolution association mapping of number of teats in pigs reveals regions controlling vertebral development.Pygo2 regulates β-catenin-induced activation of hair follicle stem/progenitor cells and skin hyperplasiaEpithelial stem cells: an epigenetic and Wnt-centric perspective.Is soy consumption good or bad for the breast?Wnt and mammary stem cells: hormones cannot fly wingless.LATS2 suppresses oncogenic Wnt signaling by disrupting β-catenin/BCL9 interaction.Pygo2 associates with MLL2 histone methyltransferase and GCN5 histone acetyltransferase complexes to augment Wnt target gene expression and breast cancer stem-like cell expansion.The epigenetic landscape of mammary gland development and functional differentiation.Key signaling nodes in mammary gland development and cancer: β-catenin.Abnormal expression of Pygopus 2 correlates with a malignant phenotype in human lung cancer.The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cellsChromatin-based mechanisms of renal epithelial differentiationPygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells.Pygopus-2 promotes invasion and metastasis of hepatic carcinoma cell by decreasing E-cadherin expression.Akt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-mediated Degradation.Wnt signaling in mammary glands: plastic cell fates and combinatorial signaling.Parathyroid hormone-related protein activates Wnt signaling to specify the embryonic mammary mesenchyme.Regeneration-associated WNT signaling is activated in long-term reconstituting AC133bright acute myeloid leukemia cells.Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.Correlation of Wnt and NOTCH pathways in esophageal squamous cell carcinoma.Chromatin effector Pygo2 mediates Wnt-notch crosstalk to suppress luminal/alveolar potential of mammary stem and basal cells.Logical design of an anti-cancer agent targeting the plant homeodomain in Pygopus2Epigenetics, Wnt signaling, and stem cells: the Pygo2 connection.
P2860
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P2860
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
description
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Juni 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/06/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/06/01)
@nl
наукова стаття, опублікована в червні 2009
@uk
مقالة علمية (نشرت في يونيو 2009)
@ar
name
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
@ast
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
@en
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
@nl
type
label
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
@ast
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
@en
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
@nl
prefLabel
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
@ast
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
@en
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
@nl
P2093
P2860
P921
P3181
P356
P1476
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
@en
P2093
Anshu Agrawal
Bingnan Gu
Catherine Rhéaume
Eva Y.-H. P. Lee
Jacqueline M. Veltmaat
Ken-Ichi Takemaru
Michael T. Lewis
P2860
P304
P3181
P356
10.1083/JCB.200810133
P407
P577
2009-06-01T00:00:00Z