The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation
about
SS18 together with animal-specific factors defines human BAF-type SWI/SNF complexesSevere pancreas hypoplasia and multicystic renal dysplasia in two human fetuses carrying novel HNF1beta/MODY5 mutationsResidual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutationSWI/SNF chromatin remodeling complexes and cancerThe SWI/SNF genetic blockade: effects in cell differentiation, cancer and developmental diseasesAnalysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiationSwitch-like genes populate cell communication pathways and are enriched for extracellular proteinsContribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells.RB1CC1 activates RB1 pathway and inhibits proliferation and cologenic survival in human cancer.Rhabdoid tumor: gene expression clues to pathogenesis and potential therapeutic targets.The SWI/SNF subunit/tumor suppressor BAF47/INI1 is essential in cell cycle arrest upon skeletal muscle terminal differentiation.Mechanisms by which SMARCB1 loss drives rhabdoid tumor growth.Recruitment of SWI/SNF complex is required for transcriptional activation of the SLC11A1 gene during macrophage differentiation of HL-60 cellsGenetic effects on DNA methylation and its potential relevance for obesity in Mexican Americans.Fibroblast growth factor receptors as novel therapeutic targets in SNF5-deleted malignant rhabdoid tumorsNon-targeted metabolomics of Brg1/Brm double-mutant cardiomyocytes reveals a novel role for SWI/SNF complexes in metabolic homeostasis.The occurrence of intracranial rhabdoid tumours in mice depends on temporal control of Smarcb1 inactivation.Establishment and characterization of MRT cell lines from genetically engineered mouse models and the influence of genetic background on their development.Chromatin and chromatin-modifying proteins in adipogenesis.How many remodelers does it take to make a brain? Diverse and cooperative roles of ATP-dependent chromatin-remodeling complexes in development.The role of INI1/hSNF5 in gene regulation and cancer.The role of SMARCB1/INI1 in development of rhabdoid tumor.Vulnerabilities of mutant SWI/SNF complexes in cancer.ARID1B is a specific vulnerability in ARID1A-mutant cancers.SNF5, a core component of the SWI/SNF complex, is necessary for p53 expression and cell survival, in part through eIF4E.SNF5 is Involved in Suppression of Hepatocellular Carcinoma Progression via TGF-Beta 1 Signaling.Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability.Dependence on PI3K/Akt signaling for malignant rhabdoid tumor cell survivalThe requirement for SNF5/INI1 in adipocyte differentiation highlights new features of malignant rhabdoid tumors.Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile.A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development.Activation of β-catenin/TCF targets following loss of the tumor suppressor SNF5.Increased DNA damage sensitivity and apoptosis in cells lacking the Snf5/Ini1 subunit of the SWI/SNF chromatin remodeling complex.GATA4 loss of function in liver cancer impedes precursor to hepatocyte transition.Hormone-response genes are direct in vivo regulatory targets of Brahma (SWI/SNF) complex function.Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria.
P2860
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P2860
The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation
description
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im September 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/09/21)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/09/21)
@nl
наукова стаття, опублікована у вересні 2005
@uk
مقالة علمية (نشرت في 21-9-2005)
@ar
name
The SWI/SNF chromatin-remodeli ...... for hepatocyte differentiation
@ast
The SWI/SNF chromatin-remodeli ...... for hepatocyte differentiation
@en
The SWI/SNF chromatin-remodeli ...... for hepatocyte differentiation
@nl
type
label
The SWI/SNF chromatin-remodeli ...... for hepatocyte differentiation
@ast
The SWI/SNF chromatin-remodeli ...... for hepatocyte differentiation
@en
The SWI/SNF chromatin-remodeli ...... for hepatocyte differentiation
@nl
prefLabel
The SWI/SNF chromatin-remodeli ...... for hepatocyte differentiation
@ast
The SWI/SNF chromatin-remodeli ...... for hepatocyte differentiation
@en
The SWI/SNF chromatin-remodeli ...... for hepatocyte differentiation
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The SWI/SNF chromatin-remodeli ...... for hepatocyte differentiation
@en
P2093
Agnès Klochendler-Yeivin
Andreas Reimann
Christian Muchardt
Laurence Fiette
Marco Pontoglio
Moshe Yaniv
Serge Garbay
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7600802
P407
P577
2005-09-21T00:00:00Z