ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling
about
Alu sequences in undifferentiated human embryonic stem cells display high levels of A-to-I RNA editingADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencingHuman BLCAP transcript: new editing events in normal and cancerous tissuesPrognostic significance of copy-number alterations in multiple myelomaAltered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNAReprogramming, Circular Reasoning and Self versus Non-self: One-Stop Shopping with RNA EditingA-to-I editing of coding and non-coding RNAs by ADARsADAR1, inosine and the immune sensing system: distinguishing self from non-selfTo edit or not to edit: regulation of ADAR editing specificity and efficiencyThe Epitranscriptome and Innate ImmunityNew Insights into the Biological Role of Mammalian ADARs; the RNA Editing ProteinsAdenosine-to-inosine RNA editing and human diseaseProtein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon responseInflammatory modulation of HSCs: viewing the HSC as a foundation for the immune responseFunctions of the RNA Editing Enzyme ADAR1 and Their Relevance to Human DiseasesRapid and dynamic transcriptome regulation by RNA editing and RNA modificationsImpact of Viral Infections on Hematopoiesis: From Beneficial to Detrimental Effects on Bone Marrow OutputThe interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replicationEnhancement of replication of RNA viruses by ADAR1 via RNA editing and inhibition of RNA-activated protein kinaseRNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKRAPOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcriptsRNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonselfFunctions and regulation of RNA editing by ADAR deaminasesMutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signatureAdenosine deaminases acting on RNA (ADARs) are both antiviral and proviralGenetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progressionADAR1 is required for hematopoietic progenitor cell survival via RNA editingRNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesisThe dynamic epitranscriptome: A to I editing modulates genetic informationMouse models for Aicardi-Goutières syndrome provide clues to the molecular pathogenesis of systemic autoimmunityCharacterizing of functional human coding RNA editing from evolutionary, structural, and dynamic perspectives.Transcript diversification in the nervous system: a to I RNA editing in CNS function and disease developmentTransient activation of hematopoietic stem and progenitor cells by IFNγ during acute bacterial infection.Induction of stress granules by interferon and down-regulation by the cellular RNA adenosine deaminase ADAR1.An RNA editor, adenosine deaminase acting on double-stranded RNA (ADAR1).Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeatsADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosisMolecular diversity through RNA editing: a balancing act.The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis.RNA surveillance-an emerging role for RNA regulatory networks in aging.
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ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling
description
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Januar 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/01/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/01/01)
@nl
наукова стаття, опублікована в січні 2009
@uk
مقالة علمية (نشرت عام 2009)
@ar
name
ADAR1 is essential for the mai ...... ession of interferon signaling
@ast
ADAR1 is essential for the mai ...... ession of interferon signaling
@en
ADAR1 is essential for the mai ...... ession of interferon signaling
@nl
type
label
ADAR1 is essential for the mai ...... ession of interferon signaling
@ast
ADAR1 is essential for the mai ...... ession of interferon signaling
@en
ADAR1 is essential for the mai ...... ession of interferon signaling
@nl
prefLabel
ADAR1 is essential for the mai ...... ession of interferon signaling
@ast
ADAR1 is essential for the mai ...... ession of interferon signaling
@en
ADAR1 is essential for the mai ...... ession of interferon signaling
@nl
P2093
P2860
P3181
P356
P1433
P1476
ADAR1 is essential for the mai ...... ession of interferon signaling
@en
P2093
Carl R. Walkley
Jochen C. Hartner
Stuart H. Orkin
P2860
P304
P3181
P356
10.1038/NI.1680
P407
P577
2009-01-01T00:00:00Z