Disruption of axo-glial junctions causes cytoskeletal disorganization and degeneration of Purkinje neuron axons
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Disrupted axo-glial junctions result in accumulation of abnormal mitochondria at nodes of ranvierWhirlin, a cytoskeletal scaffolding protein, stabilizes the paranodal region and axonal cytoskeleton in myelinated axonsDefects in myelination, paranode organization and Purkinje cell innervation in the ether lipid-deficient mouse cerebellumIn vivo deletion of immunoglobulin domains 5 and 6 in neurofascin (Nfasc) reveals domain-specific requirements in myelinated axonsGiant axon formation in mice lacking Kell, XK, or Kell and XK: animal models of McLeod neuroacanthocytosis syndromeUsing Gene Ontology to describe the role of the neurexin-neuroligin-SHANK complex in human, mouse and rat and its relevance to autismElectron tomography of paranodal septate-like junctions and the associated axonal and glial cytoskeletons in the central nervous system.Postnatal Loss of Neuronal and Glial Neurofascins Differentially Affects Node of Ranvier Maintenance and Myelinated Axon Function.Probing mechanisms of axonopathy. Part II: Protein targets of 2,5-hexanedione, the neurotoxic metabolite of the aliphatic solvent n-hexaneAxonal ensheathment and intercellular barrier formation in Drosophila.No effect of genetic deletion of contactin-associated protein (CASPR) on axonal orientation and synaptic plasticity.Myelination and regional domain differentiation of the axon.Glial ensheathment of peripheral axons in Drosophila.Spatiotemporal ablation of myelinating glia-specific neurofascin (Nfasc NF155) in mice reveals gradual loss of paranodal axoglial junctions and concomitant disorganization of axonal domains.Organization and maintenance of molecular domains in myelinated axonsRole of transverse bands in maintaining paranodal structure and axolemmal domain organization in myelinated nerve fibers: effect on longevity in dysmyelinated mutant miceThe cytoskeletal adaptor protein band 4.1B is required for the maintenance of paranodal axoglial septate junctions in myelinated axons.Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosisMyelination and axonal electrical activity modulate the distribution and motility of mitochondria at CNS nodes of Ranvier.BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells.Resilient emotionality and molecular compensation in mice lacking the oligodendrocyte-specific gene Cnp1Pinceau organization in the cerebellum requires distinct functions of neurofascin in Purkinje and basket neurons during postnatal developmentSpectrin and ankyrin-based cytoskeletons at polarized domains in myelinated axons.The septate junction protein caspr is required for structural support and retention of KCNQ4 at calyceal synapses of vestibular hair cells.Proteomic analysis of optic nerve lipid rafts reveals new paranodal proteins.GPI-anchored proteins at the node of Ranvier.Genetic dissection of myelinated axons in zebrafishConcepts for regulation of axon integrity by enwrapping glia.The node of Ranvier in CNS pathologySchwann cell myelinationAxonal domain disorganization in Caspr1 and Caspr2 mutant myelinated axons affects neuromuscular junction integrity, leading to muscle atrophy.The Axonal Cytoskeleton and the Assembly of Nodes of Ranvier.Chronic peripheral nerve compression disrupts paranodal axoglial junctions.Early and Late Loss of the Cytoskeletal Scaffolding Protein, Ankyrin G Reveals Its Role in Maturation and Maintenance of Nodes of Ranvier in Myelinated Axons.Cytoskeletal transition at the paranodes: the Achilles' heel of myelinated axons.Regulation and dysregulation of axon infrastructure by myelinating glia.Identification of a novel CNTNAP1 mutation causing arthrogryposis multiplex congenita with cerebral and cerebellar atrophy.An αII Spectrin-Based Cytoskeleton Protects Large-Diameter Myelinated Axons from Degeneration.Disruption of paranodal axo-glial interaction and/or absence of sulfatide causes irregular type I inositol 1,4,5-trisphosphate receptor deposition in cerebellar Purkinje neuron axons.
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P2860
Disruption of axo-glial junctions causes cytoskeletal disorganization and degeneration of Purkinje neuron axons
description
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2006
@ast
im März 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/03/28)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/03/28)
@nl
наукова стаття, опублікована в березні 2006
@uk
name
Disruption of axo-glial juncti ...... ation of Purkinje neuron axons
@ast
Disruption of axo-glial juncti ...... ation of Purkinje neuron axons
@en
Disruption of axo-glial juncti ...... ation of Purkinje neuron axons
@nl
type
label
Disruption of axo-glial juncti ...... ation of Purkinje neuron axons
@ast
Disruption of axo-glial juncti ...... ation of Purkinje neuron axons
@en
Disruption of axo-glial juncti ...... ation of Purkinje neuron axons
@nl
prefLabel
Disruption of axo-glial juncti ...... ation of Purkinje neuron axons
@ast
Disruption of axo-glial juncti ...... ation of Purkinje neuron axons
@en
Disruption of axo-glial juncti ...... ation of Purkinje neuron axons
@nl
P2093
P2860
P921
P356
P1476
Disruption of axo-glial juncti ...... ation of Purkinje neuron axons
@en
P2093
Anilkumar M. Pillai
Aurea D. Sousa
German P. Garcia-Fresco
Jacqueline N. Crawley
Jeffrey L. Dupree
Lino Tessarollo
Manzoor A. Bhat
Sheryl S. Moy
P2860
P304
P356
10.1073/PNAS.0601082103
P407
P577
2006-03-28T00:00:00Z