SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL
about
T cell regulation of p62(dok) (Dok1) association with Crk-LA unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding and functionCrkL is recruited through its SH2 domain to the erythropoietin receptor and plays a role in Lyn-mediated receptor signalingMultimolecular signaling complexes enable Syk-mediated signaling of CD36 internalizationUncoupling Crk signal transduction by Pseudomonas exoenzyme T.Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells.Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib.MyD88-dependent SHIP1 regulates proinflammatory signaling pathways in dendritic cells after monophosphoryl lipid A stimulation of TLR4.Rac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis.Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 1. Effects on inflammatory cell activation and chemotaxis in vitro and pharmacokinetic characterization in vivoCharacterization of AQX-1125, a small-molecule SHIP1 activator: Part 2. Efficacy studies in allergic and pulmonary inflammation models in vivo.Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes.SHIP is required for a functional hematopoietic stem cell niche.C-reactive protein inhibits insulin activation of endothelial nitric oxide synthase via the immunoreceptor tyrosine-based inhibition motif of FcgammaRIIB and SHIP-1.Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia.IkappaB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation.C-type lectin-like receptors of the dectin-1 cluster: ligands and signaling pathways.Regulation of immune cell signaling by SHIP1: A phosphatase, scaffold protein, and potential therapeutic target.How does SHIP1/2 balance PtdIns(3,4)P2 and does it signal independently of its phosphatase activity?Interaction of SAP-1, a transmembrane-type protein-tyrosine phosphatase, with the tyrosine kinase Lck. Roles in regulation of T cell function.IMPDHII protein inhibits Toll-like receptor 2-mediated activation of NF-kappaB.Frameshift mutation in the Dok1 gene in chronic lymphocytic leukemia.Differential signaling through p190 and p210 BCR-ABL fusion proteins revealed by interactome and phosphoproteome analysis.
P2860
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P2860
SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL
description
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im Januar 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/01/26)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/01/26)
@nl
наукова стаття, опублікована в січні 2001
@uk
name
SHIP1, an SH2 domain containin ...... ing complex with DOK1 and CRKL
@ast
SHIP1, an SH2 domain containin ...... ing complex with DOK1 and CRKL
@en
SHIP1, an SH2 domain containin ...... ing complex with DOK1 and CRKL
@nl
type
label
SHIP1, an SH2 domain containin ...... ing complex with DOK1 and CRKL
@ast
SHIP1, an SH2 domain containin ...... ing complex with DOK1 and CRKL
@en
SHIP1, an SH2 domain containin ...... ing complex with DOK1 and CRKL
@nl
prefLabel
SHIP1, an SH2 domain containin ...... ing complex with DOK1 and CRKL
@ast
SHIP1, an SH2 domain containin ...... ing complex with DOK1 and CRKL
@en
SHIP1, an SH2 domain containin ...... ing complex with DOK1 and CRKL
@nl
P2093
P2860
P356
P1476
SHIP1, an SH2 domain containin ...... ing complex with DOK1 and CRKL
@en
P2093
J. D. Griffin
L. R. Rohrschneider
M. Sattler
Y. B. Pride
P2860
P304
P356
10.1074/JBC.M006250200
P407
P577
2001-01-26T00:00:00Z