Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene
about
Research resource: Haploinsufficiency of receptor activity-modifying protein-2 (RAMP2) causes reduced fertility, hyperprolactinemia, skeletal abnormalities, and endocrine dysfunction in miceAdrenomedullin signaling is necessary for murine lymphatic vascular development.G protein-coupled receptors: what a difference a 'partner' makesThe ADMR receptor mediates the effects of adrenomedullin on pancreatic cancer cells and on cells of the tumor microenvironmentReceptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old ageReduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in miceRole of calcitonin receptor-like receptor in colonic motility and inflammationEpicardial-derived adrenomedullin drives cardiac hyperplasia during embryogenesis.Activation of calcitonin receptor and calcitonin receptor-like receptor by membrane-anchored ligands.Calcitonin-gene-related peptide stimulates stromal cell osteogenic differentiation and inhibits RANKL induced NF-kappaB activation, osteoclastogenesis and bone resorption.Decoy receptor CXCR7 modulates adrenomedullin-mediated cardiac and lymphatic vascular development.Characteristics of multi-organ lymphangiectasia resulting from temporal deletion of calcitonin receptor-like receptor in adult mice.Deficiency of RAMP1 attenuates antigen-induced airway hyperresponsiveness in miceThe role of imprinted genes in fetal growth abnormalities.Regulation of oocyte and cumulus cell interactions by intermedin/adrenomedullin 2.Loss of receptor activity-modifying protein 3 exacerbates cardiac hypertrophy and transition to heart failure in a sex-dependent manner.Adrenomedullin Function in Vascular Endothelial Cells: Insights from Genetic Mouse Models.Evidence for a functional adrenomedullin signaling pathway in the mouse retina.Transcription factor ISL1 is essential for pacemaker development and function.Mice heterozygous for adrenomedullin exhibit a more extreme inflammatory response to endotoxin-induced septic shock.Blood is thicker than lymphA co-housing strategy to improve fecundity of mice in timed matings.Hypercholesterolemia potentiates aortic endothelial response to inhaled diesel exhaustMicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturationLack of adrenomedullin in the mouse brain results in behavioral changes, anxiety, and lower survival under stress conditions.Fetal-derived adrenomedullin mediates the innate immune milieu of the placenta.Understanding RAMPs through genetically engineered mouse models.Prevention of Bone Loss in a Model of Postmenopausal Osteoporosis through Adrenomedullin Inhibition.Roles of CLR/RAMP receptor signaling in reproduction and development.G protein-coupled receptors as potential drug targets for lymphangiogenesis and lymphatic vascular diseases.Lymphatic deletion of calcitonin receptor-like receptor exacerbates intestinal inflammation.Adrenomedullin and tumour microenvironment.Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells.Why increased nuchal translucency is associated with congenital heart disease: a systematic review on genetic mechanisms.Adrenomedullin in lymphangiogenesis: from development to disease.Adrenomedullin - new perspectives of a potent peptide hormone.Endothelial Restoration of Receptor Activity-Modifying Protein 2 Is Sufficient to Rescue Lethality, but Survivors Develop Dilated Cardiomyopathy.Targeting orphan G protein-coupled receptors for the treatment of diabetes and its complications: C-peptide and GPR146.Identification of key residues involved in adrenomedullin binding to the AM1 receptorIntermedin (adrenomedullin2) stabilizes the endothelial barrier and antagonizes thrombin-induced barrier failure in endothelial cell monolayers.
P2860
Q24603724-BEE313E1-BD43-4F02-BFE0-22BBD2FCFE19Q24671300-FED4EBBF-0C7B-4723-A770-7A8F91D8479DQ27023482-4111F86C-5436-4412-BB57-A22343736ACFQ27339492-E909C34E-4BD4-4257-9441-F302EE290705Q28300031-4C44D3B5-58A2-4621-9B70-71443561DA3FQ28510935-939738A0-2F55-4AE1-BB27-F9BE210EB400Q28582321-3F329AEB-4A30-45B1-B9F3-3725173835A1Q33564987-E233E65B-2259-4285-A9E9-C0A25931FF37Q33569613-BE6D6E08-BAAE-49AB-9A0D-7C722BDFBED9Q33787854-0D42AEE1-8776-4730-A9C8-EE2FC637CE83Q34199625-411D0D11-CA36-4F7E-85CD-DF5A84E640E3Q34428530-83975900-5412-4FFF-BBC5-89726551FA74Q35204352-4750A42E-6E68-462A-AC5A-474B6479EC99Q35295496-F2591CDB-DAD3-47C5-AA68-4B600AA60D1BQ35604620-C9607A3C-832A-473F-A2DA-4A574838E7DAQ35668366-78F88FAD-AA70-4BDC-B0D6-18CCF7F8CDF7Q35952350-273349CD-5BD0-48B2-BB43-973DF2978079Q36015785-6CD891B0-971B-4A47-8E5A-575A1E050767Q36040426-4904A1EE-5487-462C-B420-A27C82999275Q36238753-90D33465-5F40-4084-8042-DF1BF6CEAA52Q36287304-B74A248F-B0AB-4B13-A5D3-8DBE3C75DB48Q36302318-8588574E-DFAB-4F9A-A7AE-ABA9EB557490Q36709811-A0E08BCE-FF6C-4660-8DCA-205B8D1AD067Q36799157-BB1CB79A-5DD4-4040-BE63-28FE8BD01DDEQ36858688-0D89A555-F55F-4CCC-8393-D186997D592EQ36890958-13DD8C0D-A2F5-4A3B-B176-AE0145FFC2E5Q36960849-3A620768-0D06-4EC5-AE0F-8756D7053FE2Q37054851-CF8DFC01-72CF-463D-97C5-A0950C52ECF1Q37262321-88D3CB5E-3EE7-4A1B-827D-106B7EA6EAC0Q37385266-7C6D451D-EC6D-4E68-98DE-38EB064C76ADQ37711794-80875E71-169A-4D69-8979-8CE69A4D6CF8Q38283129-0C0A093A-A803-40E7-A735-178CDF1206DEQ38347480-F59BCF76-FD57-421F-AFD4-E4B72FFCC681Q38366535-A5B423FE-9002-4EFE-9677-152B67F5ECE6Q38466384-E65788D0-BBC8-4497-B168-65A82C6DF62DQ38763013-360AA45E-38C8-4D80-A372-426C7BA85DF1Q38842847-879D8EAE-E44F-4C2C-843C-8F715AB1C13DQ38866310-911B8600-4545-460A-B6EA-6C7B59943B79Q39989856-249C479B-19BF-417A-96F8-9D023AC02B03Q40218242-240CA76F-3DEA-4EE2-B718-E84E791E06DB
P2860
Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene
description
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im April 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/04/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/04/01)
@nl
наукова стаття, опублікована у квітні 2006
@uk
مقالة علمية (نشرت في أبريل 2006)
@ar
name
Hydrops fetalis, cardiovascula ...... in receptor-like receptor gene
@ast
Hydrops fetalis, cardiovascula ...... in receptor-like receptor gene
@en
Hydrops fetalis, cardiovascula ...... in receptor-like receptor gene
@nl
type
label
Hydrops fetalis, cardiovascula ...... in receptor-like receptor gene
@ast
Hydrops fetalis, cardiovascula ...... in receptor-like receptor gene
@en
Hydrops fetalis, cardiovascula ...... in receptor-like receptor gene
@nl
prefLabel
Hydrops fetalis, cardiovascula ...... in receptor-like receptor gene
@ast
Hydrops fetalis, cardiovascula ...... in receptor-like receptor gene
@en
Hydrops fetalis, cardiovascula ...... in receptor-like receptor gene
@nl
P2093
P2860
P921
P3181
P1476
Hydrops fetalis, cardiovascula ...... in receptor-like receptor gene
@en
P2093
Carrie L. Gibbons
Kathleen M. Caron
Kimberly Fritz-Six
Oliver Smithies
Ryan T. Dackor
William P. Dunworth
P2860
P304
P3181
P356
10.1128/MCB.26.7.2511-2518.2006
P407
P577
2006-04-01T00:00:00Z