Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta
about
An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machineSteroid Receptor-Associated Immunophilins: A Gateway to Steroid SignallingFKBP51 and FKBP52 in signaling and diseaseEnhancement of stress resilience through histone deacetylase 6-mediated regulation of glucocorticoid receptor chaperone dynamics.Cell cycle phase regulates glucocorticoid receptor functionAn inducible expression system to measure rhodopsin transport in transgenic Xenopus rod outer segmentsGlucocorticoid-independent modulation of GR activity: Implications for immunotherapyThe roles of co-chaperone CCRP/DNAJC7 in Cyp2b10 gene activation and steatosis development in mouse liversSubcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowthNucleoporin Nup62 maintains centrosome homeostasisDevelopment and validation of a high-content screening assay to identify inhibitors of cytoplasmic dynein-mediated transport of glucocorticoid receptor to the nucleus.Hormone binding and co-regulator binding to the glucocorticoid receptor are allosterically coupled.Hsp90 directly modulates the spatial distribution of AF9/MLLT3 and affects target gene expression.OSBP-related protein 8 (ORP8) regulates plasma and liver tissue lipid levels and interacts with the nucleoporin Nup62Influenza virus infection induces the nuclear relocalization of the Hsp90 co-chaperone p23 and inhibits the glucocorticoid receptor response.Nuclear distributions of NUP62 and NUP214 suggest architectural diversity and spatial patterning among nuclear pore complexes.Heat shock protein 83 (Hsp83) facilitates methoprene-tolerant (Met) nuclear import to modulate juvenile hormone signaling.Cytoplasmic travels of the ecdysteroid receptor in target cells: pathways for both genomic and non-genomic actions.Role for NUP62 depletion and PYK2 redistribution in dendritic retraction resulting from chronic stressControl of steroid receptor dynamics and function by genomic actions of the cochaperones p23 and Bag-1LThe -144C/A polymorphism in the promoter of HSP90beta is associated with multiple organ dysfunction scoresRegulation of steroid hormone receptor function by the 52-kDa FK506-binding protein (FKBP52).The 90-kDa heat-shock protein (Hsp90)-binding immunophilin FKBP51 is a mitochondrial protein that translocates to the nucleus to protect cells against oxidative stress.Fluorescent protein-labeled glucocorticoid receptor alpha isoform trafficking in cultured human trabecular meshwork cells.The neuroregenerative mechanism mediated by the Hsp90-binding immunophilin FKBP52 resembles the early steps of neuronal differentiation.Stress and glucocorticoid receptor transcriptional programming in time and space: Implications for the brain-gut axis.70-kDa heat shock cognate protein hsc70 mediates calmodulin-dependent nuclear import of the sex-determining factor SRYSGT1 is required in PcINF1/SRC2-1 induced pepper defense response by interacting with SRC2-1Gedunin inactivates the co-chaperone p23 protein causing cancer cell death by apoptosis.A ligand-specific kinetic switch regulates glucocorticoid receptor trafficking and function.MicroRNA-100/99a, deregulated in acute lymphoblastic leukaemia, suppress proliferation and promote apoptosis by regulating the FKBP51 and IGF1R/mTOR signalling pathwaysDynamic mitochondrial-nuclear redistribution of the immunophilin FKBP51 is regulated by the PKA signaling pathway to control gene expression during adipocyte differentiationOn the trail of the glucocorticoid receptor: into the nucleus and back.Regulation of the glucocorticoid response to stress-related disorders by the Hsp90-binding immunophilin FKBP51.Hsp90-binding immunophilins as a potential new platform for drug treatment.Biological relevance of Hsp90-binding immunophilins in cancer development and treatment.HSP90AB1: Helping the good and the bad.Glucocorticoid therapy and ocular hypertension.New Insights in Glucocorticoid Receptor Signaling-More Than Just a Ligand-Binding ReceptorThe hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events.
P2860
Q21134999-16C7C588-67B4-4F4B-B3A6-5CDC270AAD30Q26801686-6D87AE8C-4978-4ABF-8EF0-93892750E708Q26861304-F290F45B-F131-4D2F-98F2-ACBEA873D5B0Q27328366-ED56ECC6-4FDC-4D6D-979C-2E0926FA98ADQ27331735-0746AAD5-D84F-4068-A0D1-85AE5DA4CA1DQ27342685-6A30B604-499D-4D0B-B5F9-4A591BB8E8E4Q28077040-378CB471-2C86-487D-841E-A51C93303558Q28542861-1B47D922-89C6-479C-8C02-FD868C66069DQ28573222-AA24DF41-804B-4A6C-81A5-29DF4D6AAA7DQ28910450-8DBEA15B-4F15-405E-A768-AFDE69F13E78Q30416877-26FA4B0B-292A-49B9-9138-A605B93D00EBQ33545556-3EE4343F-DF67-4360-BA7D-03FB0EA6FCE9Q33782481-C0D9F573-00F8-4433-965E-A363C6636C91Q33941203-A3462537-9F34-4597-853B-8A426D674EA1Q33997127-3E9B8558-438F-49FA-96D1-B932E86401DDQ34257196-BF6505E6-E032-42F0-9D5D-608229A7D998Q34283559-89AA16FE-1642-46AD-AC31-6FC501EE0BFBQ34288842-B654C42F-501C-4C1D-B6AC-49B6774ECB76Q34525933-64E6D0C5-8DA8-42A2-A4FC-EB169F08B95CQ34564782-E55F29DA-B179-4072-8084-E23E8B4ED7B4Q34629884-608EE3D8-10F6-4AB6-A255-634A644056FFQ35165175-DF075531-1F43-4026-9C20-8552BF66EDD8Q35314400-84FE1845-7799-4902-B9F1-217E46C99751Q36035015-559AB4F8-2B76-4AA7-8E3D-A67BB0C0F49EQ36159195-AF42C7A8-29FE-4219-8187-8AFF90D87E56Q36397888-F0455CA5-10A5-44EC-850D-5B1FB600864FQ36596259-1E19343F-33D4-4167-BFBB-58DB9201A7BDQ36602359-67D331FC-83F3-4F63-90F0-779F42936346Q36666275-97A05898-7E9A-4EA5-9B2B-E7E8BDF87538Q37012031-5CCD5C3E-9529-4A07-ACED-065DDA1CD830Q37235553-60F2E002-029A-4120-911B-38D314793921Q37349119-8180638C-BC58-44F0-B1CC-C47E158862A8Q37939423-95A632A4-8F34-49CA-915A-CDEB42FD4FA8Q38006721-C72C3BA2-2C29-4041-842F-DD6769159C62Q38097870-9268140E-00CE-4666-8394-934562B878E4Q38371280-D2CA1F6F-64E6-4260-A09D-7B557D3BB7B8Q38584468-B5DDFE6D-768E-4C48-934F-C167E82F0A32Q38889124-0C99A32E-C2E5-42F0-93D2-B349B18E7DACQ38951098-1C50F92C-5CCC-439F-88FA-1A79CC8462E5Q39758279-C8E6A768-B6F3-40AF-B7D2-9230D48ABCE7
P2860
Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta
description
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im September 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/09/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/09/01)
@nl
наукова стаття, опублікована у вересні 2009
@uk
مقالة علمية (نشرت في سبتمبر 2009)
@ar
name
Nuclear import of the glucocor ...... n with Nup62 and importin beta
@ast
Nuclear import of the glucocor ...... n with Nup62 and importin beta
@en
Nuclear import of the glucocor ...... n with Nup62 and importin beta
@nl
type
label
Nuclear import of the glucocor ...... n with Nup62 and importin beta
@ast
Nuclear import of the glucocor ...... n with Nup62 and importin beta
@en
Nuclear import of the glucocor ...... n with Nup62 and importin beta
@nl
prefLabel
Nuclear import of the glucocor ...... n with Nup62 and importin beta
@ast
Nuclear import of the glucocor ...... n with Nup62 and importin beta
@en
Nuclear import of the glucocor ...... n with Nup62 and importin beta
@nl
P2093
P2860
P921
P356
P1476
Nuclear import of the glucocor ...... n with Nup62 and importin beta
@en
P2093
Alejandra Erlejman
Celso Gomez-Sanchez
Gisela Mazaira
Graciela Piwien Pilipuk
P2860
P304
P356
10.1128/MCB.00649-09
P407
P577
2009-07-06T00:00:00Z