about
Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPasesA flippase-independent function of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1, is required for apical protein expression and microvillus formation in polarized epithelial cellsP4-ATPases as Phospholipid Flippases-Structure, Function, and EnigmasMammalian P4-ATPases and ABC transporters and their role in phospholipid transportMutations in a P-type ATPase gene cause axonal degenerationThe Essential Neo1 Protein from Budding Yeast Plays a Role in Establishing Aminophospholipid Asymmetry of the Plasma Membrane.Directed evolution of a sphingomyelin flippase reveals mechanism of substrate backbone discrimination by a P4-ATPase.P4-ATPases: lipid flippases in cell membranesPhospholipase D2 mediates signaling by ATPase class I type 8B membrane 1P4 ATPases: flippases in health and diseasePhospholipid flippase ATP8A2 is required for normal visual and auditory function and photoreceptor and spiral ganglion cell survival.Genetics of auditory mechano-electrical transduction.Large membrane domains in hair bundles specify spatially constricted radixin activation.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Bile formation and secretion.Functions of phospholipid flippases.ATP8B1 gene expression is driven by a housekeeping-like promoter independent of bile acids and farnesoid X receptor.Mutational analysis of ATP8B1 in patients with chronic pancreatitis.Description of two new ABCB11 mutations responsible for type 2 benign recurrent intrahepatic cholestasis in a French-Canadian familyThe Drosophila melanogaster phospholipid flippase dATP8B is required for odorant receptor functionCritical role of a transmembrane lysine in aminophospholipid transport by mammalian photoreceptor P4-ATPase ATP8A2Identification of residues defining phospholipid flippase substrate specificity of type IV P-type ATPases.Phospholipid flippases: building asymmetric membranes and transport vesicles.Mutations in OTOGL, encoding the inner ear protein otogelin-like, cause moderate sensorineural hearing loss.Biochemical characterization of P4-ATPase mutations identified in patients with progressive familial intrahepatic cholestasisMissense mutation in the ATPase, aminophospholipid transporter protein ATP8A2 is associated with cerebellar atrophy and quadrupedal locomotionType IV P-type ATPases distinguish mono- versus diacyl phosphatidylserine using a cytofacial exit gate in the membrane domain.Localization, purification, and functional reconstitution of the P4-ATPase Atp8a2, a phosphatidylserine flippase in photoreceptor disc membranes.Clinical utility gene card for: progressive familial intrahepatic cholestasis type 1.Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2.P4 ATPases--the physiological relevance of lipid flipping transporters.Biochemical and cellular functions of P4 ATPases.Pumping lipids with P4-ATPases.Dynamic transbilayer lipid asymmetry.Canalicular ABC transporters and liver disease.Current and future therapies for inherited cholestatic liver diseases.Critical role of the beta-subunit CDC50A in the stable expression, assembly, subcellular localization, and lipid transport activity of the P4-ATPase ATP8A2Liver disease without flipping: new functions of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1.ATP8B1 and ABCB11 analysis in 62 children with normal gamma-glutamyl transferase progressive familial intrahepatic cholestasis (PFIC): phenotypic differences between PFIC1 and PFIC2 and natural history.Total internal biliary diversion during liver transplantation for type 1 progressive familial intrahepatic cholestasis: a novel approach.
P2860
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P2860
description
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2009
@ast
im Juni 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/06/16)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/06/16)
@nl
наукова стаття, опублікована в червні 2009
@uk
name
ATP8B1 is essential for maintaining normal hearing
@ast
ATP8B1 is essential for maintaining normal hearing
@en
ATP8B1 is essential for maintaining normal hearing
@nl
type
label
ATP8B1 is essential for maintaining normal hearing
@ast
ATP8B1 is essential for maintaining normal hearing
@en
ATP8B1 is essential for maintaining normal hearing
@nl
prefLabel
ATP8B1 is essential for maintaining normal hearing
@ast
ATP8B1 is essential for maintaining normal hearing
@en
ATP8B1 is essential for maintaining normal hearing
@nl
P2093
P2860
P3181
P356
P1476
ATP8B1 is essential for maintaining normal hearing
@en
P2093
Andy J. Beynon
Anneke Joosten
Bert A. van Zanten
Bibian M. van Leeuwen
Denis H. A. van Beurden
Janneke M. Stapelbroek
Jo H. A. J. Curfs
Laura Bull
Leo W. J. Klomp
Lieke M. van der Velden
P2860
P304
P3181
P356
10.1073/PNAS.0807919106
P407
P577
2009-06-16T00:00:00Z