Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs
about
Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-pairedRegulation of number and size of digits by posterior Hox genes: A dose-dependent mechanism with potential evolutionary implicationsSynpolydactyly phenotypes correlate with size of expansions in HOXD13 polyalanine tractInhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturationImpaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice.Deletions in HOXD13 segregate with an identical, novel foot malformation in two unrelated families.Modeling Hox gene regulation in digits: reverse collinearity and the molecular origin of thumbnessMutations in HOXD13 underlie syndactyly type V and a novel brachydactyly-syndactyly syndromeHomology of the reptilian coracoid and a reappraisal of the evolution and development of the amniote pectoral apparatusInfertility in adult hypodactyly mice is associated with hypoplasia of distal reproductive structuresHuman HOX gene mutationsLimb malformations and the human HOX genesBackfoot is a novel homeobox gene expressed in the mesenchyme of developing hind limbHoxc13 mutant mice lack external hairHoxd13 and Hoxa13 directly control the expression of the EphA7 Ephrin tyrosine kinase receptor in developing limbsRepression by HoxA7 is mediated by the homeodomain and the modulatory action of its N-terminal-arm residuesOcular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiationTissue-specific requirements of beta-catenin in external genitalia developmentGsh-1: a novel murine homeobox gene expressed in the central nervous systemFunction of the Evx-2 gene in the morphogenesis of vertebrate limbsA general scenario of Hox gene inventory variation among major sarcopterygian lineagesTurtle and mammal penis designs are anatomically convergentCell lineage transport: a mechanism for molecular gradient formationGain of function mutations for paralogous Hox genes: implications for the evolution of Hox gene functionFossils, genes and the evolution of animal limbsEvaluation of candidate genes for familial brachydactyly.Exploring the effects of gene dosage on mandible shape in mice as a model for studying the genetic basis of natural variationVertebrate evolution: the developmental origins of adult variation.Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation.Missense mutations in the homeodomain of HOXD13 are associated with brachydactyly types D and E.Genetic disorders of the skeleton: a developmental approachGenetic and physical mapping of the mouse Ulnaless locus.Perspectives on the evolutionary origin of tetrapod limbs.HoxD cluster scanning deletions identify multiple defects leading to paralysis in the mouse mutant Ironside.Exclusion of WTAP and HOXA13 as candidate genes for isolated hypospadias.Developmental heterochrony and the evolution of autistic perception, cognition and behaviorHoxd13 expression in the developing limbs of the short-tailed fruit bat, Carollia perspicillata.Posterior Hox gene expression in developing genitalia.The road to embryologically based dose-response models.Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice.
P2860
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P2860
Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs
description
1993 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1993
@ast
im November 1993 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1993/11/05)
@sk
vědecký článek publikovaný v roce 1993
@cs
wetenschappelijk artikel (gepubliceerd op 1993/11/05)
@nl
наукова стаття, опублікована в листопаді 1993
@uk
مقالة علمية (نشرت في 5-11-1993)
@ar
name
Disruption of the Hoxd-13 gene ...... ng to mice with neotenic limbs
@ast
Disruption of the Hoxd-13 gene ...... ng to mice with neotenic limbs
@en
Disruption of the Hoxd-13 gene ...... ng to mice with neotenic limbs
@nl
type
label
Disruption of the Hoxd-13 gene ...... ng to mice with neotenic limbs
@ast
Disruption of the Hoxd-13 gene ...... ng to mice with neotenic limbs
@en
Disruption of the Hoxd-13 gene ...... ng to mice with neotenic limbs
@nl
prefLabel
Disruption of the Hoxd-13 gene ...... ng to mice with neotenic limbs
@ast
Disruption of the Hoxd-13 gene ...... ng to mice with neotenic limbs
@en
Disruption of the Hoxd-13 gene ...... ng to mice with neotenic limbs
@nl
P2093
P50
P3181
P1433
P1476
Disruption of the Hoxd-13 gene ...... ng to mice with neotenic limbs
@en
P2093
Andrée Dierich
Brigitte Schuhbaur
Marianne LeMeur
P304
P3181
P356
10.1016/0092-8674(93)90378-4
P407
P577
1993-11-05T00:00:00Z