Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
about
An Arabidopsis immunophilin, AtFKBP12, binds to AtFIP37 (FKBP interacting protein) in an interaction that is disrupted by FK506Transforming growth factor-beta receptor-associated protein 1 is a Smad4 chaperoneReceptor accessory folding helper enzymes: the functional role of peptidyl prolyl cis/trans isomerasesInteraction of BMP10 with Tcap may modulate the course of hypertensive cardiac hypertrophyKinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparksSmad7 is required for the development and function of the heartIn situ modulation of the human cardiac ryanodine receptor (hRyR2) by FKBP12.6Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptormTOR signaling: at the crossroads of plasticity, memory and diseaseRemodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacityIdentification of cardiac malformations in mice lacking Ptdsr using a novel high-throughput magnetic resonance imaging techniqueTowards in vivo amplification: Overcoming hurdles in the use of hematopoietic stem cells in transplantation and gene therapyAnalysing the visible conformational substates of the FK506-binding protein FKBP12Structural basis of conformational transitions in the active site and 80′s loop in the FK506-binding protein FKBP12Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificityFAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast.Hmo1p, a high mobility group 1/2 homolog, genetically and physically interacts with the yeast FKBP12 prolyl isomeraseCyclophilin A and Ess1 interact with and regulate silencing by the Sin3-Rpd3 histone deacetylase.Dysregulated ryanodine receptors mediate cellular toxicity: restoration of normal phenotype by FKBP12.6FKBP12 binding modulates ryanodine receptor channel gatingIsolation and proteomic characterization of human Parvulin-associating preribosomal ribonucleoprotein complexesLocalization of the 12.6-kDa FK506-binding protein (FKBP12.6) binding site to the NH2-terminal domain of the cardiac Ca2+ release channel (ryanodine receptor)Interaction of FKBP12.6 with the cardiac ryanodine receptor C-terminal domainFKBP12 modulation of the binding of the skeletal ryanodine receptor onto the II-III loop of the dihydropyridine receptor.Distinct pathways involving the FK506-binding proteins 12 and 12.6 underlie IL-2-versus IL-15-mediated proliferation of T cellsDissociation of FKBP12.6 from ryanodine receptor type 2 is regulated by cyclic ADP-ribose but not beta-adrenergic stimulation in mouse cardiomyocytesA protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification.BMP10 is essential for maintaining cardiac growth during murine cardiogenesisTGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytesRemoval of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behaviorKnockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy PhenotypeFK506 and the role of the immunophilin FKBP-52 in nerve regeneration.Identification and comparative analysis of sixteen fungal peptidyl-prolyl cis/trans isomerase repertoires.Critical roles of miRNA-mediated regulation of TGFβ signalling during mouse cardiogenesis.Familial occurrence of isolated non-compaction cardiomyopathy.The immunophilin-interacting protein AtFIP37 from Arabidopsis is essential for plant development and is involved in trichome endoreduplication.Functional identification of distinct sets of antitumor activities mediated by the FKBP gene family.A simple and efficient route to the FKBP-binding domain from rapamycinRyanodine receptors: structure, expression, molecular details, and function in calcium release.Fenobam promoted the neuroprotective effect of PEP-1-FK506BP following oxidative stress by increasing its transduction efficiency.
P2860
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P2860
Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
description
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 1998
@ast
scientific journal article
@en
vedecký článok (publikovaný 1998/01/29)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/01/29)
@nl
наукова стаття, опублікована в січні 1998
@uk
مقالة علمية (نشرت في 29-1-1998)
@ar
name
Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
@ast
Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
@en
Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
@nl
type
label
Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
@ast
Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
@en
Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
@nl
prefLabel
Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
@ast
Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
@en
Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
@nl
P2093
P2860
P3181
P356
P1433
P1476
Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
@en
P2093
B. Aghdasi
D. L. Armstrong
L. M. Mathews
M. D. Schneider
M. J. Charng
M. M. Matzuk
S. L. Hamilton
P2860
P2888
P304
P3181
P356
10.1038/35146
P407
P577
1998-01-29T00:00:00Z
P5875
P6179
1048915037