The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission
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The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptorsMolecular model of cannabis sensitivity in developing neuronal circuitsControl of synaptic function by endocannabinoid-mediated retrograde signalingParsing the players: 2-arachidonoylglycerol synthesis and degradation in the CNSDopaminergic modulation of striatal neurons, circuits, and assembliesWhy do cannabinoid receptors have more than one endogenous ligand?Chemical probes of endocannabinoid metabolismTherapeutic potential of monoacylglycerol lipase inhibitorsModulation of the endocannabinoid system: vulnerability factor and new treatment target for stimulant addictionDifferential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfindingFever Is Mediated by Conversion of Endocannabinoid 2-Arachidonoylglycerol to Prostaglandin E2Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndromeChronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system.The evolution and comparative neurobiology of endocannabinoid signallingGlucocorticoids interact with the hippocampal endocannabinoid system in impairing retrieval of contextual fear memory.Sustained firing of cartwheel cells in the dorsal cochlear nucleus evokes endocannabinoid release and retrograde suppression of parallel fiber synapses.RGS4 is required for dopaminergic control of striatal LTD and susceptibility to parkinsonian motor deficitsEndocannabinoids shape accumbal encoding of cue-motivated behavior via CB1 receptor activation in the ventral tegmentum.Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling.Endogenous cannabinoid signaling at inhibitory interneurons.Localization of the cannabinoid CB1 receptor and the 2-AG synthesizing (DAGLĪ±) and degrading (MAGL, FAAH) enzymes in cells expressing the Ca(2+)-binding proteins calbindin, calretinin, and parvalbumin in the adult rat hippocampus.Endocannabinoids generated by Ca2+ or by metabotropic glutamate receptors appear to arise from different pools of diacylglycerol lipaseActivation of TRPC6 channels promotes endocannabinoid biosynthesis in neuronal CAD cells.Distinct endocannabinoid control of GABA release at perisomatic and dendritic synapses in the hippocampus.Chemical approaches to therapeutically target the metabolism and signaling of the endocannabinoid 2-AG and eicosanoidsBiosynthesis and degradation of the endocannabinoid 2-arachidonoylglycerol.Modulation of the serotonin system by endocannabinoid signalingRequirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections.Multiple functions of endocannabinoid signaling in the brain.Endocannabinoid signaling and synaptic function.Metabolism of endocannabinoids and related N-acylethanolamines: canonical and alternative pathways.Regulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoyl-glycerol and arachidonoyl-ethanolamide, and their metabolites.Cannabinoids facilitate the swallowing reflex elicited by the superior laryngeal nerve stimulation in rats.Developmental increase in hippocampal endocannabinoid mobilization: role of metabotropic glutamate receptor subtype 5 and phospholipase C.Developmental and visual input-dependent regulation of the CB1 cannabinoid receptor in the mouse visual cortexUnique inhibitory synapse with particularly rich endocannabinoid signaling machinery on pyramidal neurons in basal amygdaloid nucleusA biophysical model of endocannabinoid-mediated short term depression in hippocampal inhibitionHippocampal metaplasticity is required for the formation of temporal associative memories.Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation.Central endocannabinoid signaling regulates hepatic glucose production and systemic lipolysis
P2860
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P2860
The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission
description
2010 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« ÕÕ„ÕæÖÕøÖÕ”ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
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@hyw
2010 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« ÖÕ„ÕæÖÕ¾Õ”ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
artĆculu cientĆficu espublizĆ”u en 2010
@ast
im Februar 2010 verƶffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedeckĆ½ ÄlĆ”nok (publikovanĆ½ 2010/02/11)
@sk
vÄdeckĆ½ ÄlĆ”nek publikovanĆ½ v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/02/11)
@nl
Š½Š°ŃŠŗŠ¾Š²Š° ŃŃŠ°ŃŃŃ, Š¾ŠæŃŠ±Š»ŃŠŗŠ¾Š²Š°Š½Š° Š² Š»ŃŃŠ¾Š¼Ń 2010
@uk
Ł
ŁŲ§ŁŲ© Ų¹ŁŁ
ŁŲ© (ŁŲ“Ų±ŲŖ ŁŁ 11-2-2010)
@ar
name
The endocannabinoid 2-arachido ...... ssion of synaptic transmission
@ast
The endocannabinoid 2-arachido ...... ssion of synaptic transmission
@en
The endocannabinoid 2-arachido ...... ssion of synaptic transmission
@nl
type
label
The endocannabinoid 2-arachido ...... ssion of synaptic transmission
@ast
The endocannabinoid 2-arachido ...... ssion of synaptic transmission
@en
The endocannabinoid 2-arachido ...... ssion of synaptic transmission
@nl
prefLabel
The endocannabinoid 2-arachido ...... ssion of synaptic transmission
@ast
The endocannabinoid 2-arachido ...... ssion of synaptic transmission
@en
The endocannabinoid 2-arachido ...... ssion of synaptic transmission
@nl
P2093
P921
P3181
P1433
P1476
The endocannabinoid 2-arachido ...... ssion of synaptic transmission
@en
P2093
Asami Tanimura
Kenji Sakimura
Kouichi Hashimoto
Manabu Abe
Masahiko Watanabe
Masanobu Kano
Maya Yamazaki
Motokazu Uchigashima
Shinya Kawata
Takao Shimizu
P304
P3181
P356
10.1016/J.NEURON.2010.01.021
P407
P577
2010-02-11T00:00:00Z