Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs protein translation and contributes to myopathy in mice and humans

Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs protein translation and contributes to myopathy in mice and humans

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http://www.wikidata.org/entity/Q28594840
Nucleoside modifications in the regulation of gene expression: focus on tRNATRMT5 Mutations Cause a Defect in Post-transcriptional Modification of Mitochondrial tRNA Associated with Multiple Respiratory-Chain DeficienciesMtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver InjuryLack of tRNA-i6A modification causes mitochondrial-like metabolic deficiency in S. pombe by limiting activity of cytosolic tRNATyr, not mito-tRNA.Roles of Fe-S proteins: from cofactor synthesis to iron homeostasis to protein synthesis.A deafness-associated tRNAAsp mutation alters the m1G37 modification, aminoacylation and stability of tRNAAsp and mitochondrial function.Post-transcriptional gene regulation by mRNA modifications.Reactive sulfur species regulate tRNA methylthiolation and contribute to insulin secretion.Biosynthesis of Sulfur-Containing tRNA Modifications: A Comparison of Bacterial, Archaeal, and Eukaryotic Pathways.Diverse Mechanisms of Sulfur Decoration in Bacterial tRNA and Their Cellular Functions.The modified base isopentenyladenosine and its derivatives in tRNA.Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue.Cdk5rap1-mediated 2-methylthio-N6-isopentenyladenosine modification is absent from nuclear-derived RNA species.TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival.The mitochondrial epitranscriptome: the roles of RNA modifications in mitochondrial translation and human disease.CDK5RAP1 targeting NF-κB signaling pathway in human malignant melanoma A375 cell apoptosis.Reduction of Movement in Neurological Diseases: Effects on Neural Stem Cells Characteristics.
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Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs protein translation and contributes to myopathy in mice and humans

Item
http://www.wikidata.org/entity/Q28594840
description
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2015
@ast
im März 2015 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2015/03/03)
@sk
vědecký článek publikovaný v roce 2015
@cs
wetenschappelijk artikel (gepubliceerd op 2015/03/03)
@nl
наукова стаття, опублікована в березні 2015
@uk
مقالة علمية (نشرت في 3-3-2015)
@ar
name
Cdk5rap1-mediated 2-methylthio ...... to myopathy in mice and humans
@ast
Cdk5rap1-mediated 2-methylthio ...... to myopathy in mice and humans
@en
Cdk5rap1-mediated 2-methylthio ...... to myopathy in mice and humans
@nl
type
label
Cdk5rap1-mediated 2-methylthio ...... to myopathy in mice and humans
@ast
Cdk5rap1-mediated 2-methylthio ...... to myopathy in mice and humans
@en
Cdk5rap1-mediated 2-methylthio ...... to myopathy in mice and humans
@nl
prefLabel
Cdk5rap1-mediated 2-methylthio ...... to myopathy in mice and humans
@ast
Cdk5rap1-mediated 2-methylthio ...... to myopathy in mice and humans
@en
Cdk5rap1-mediated 2-methylthio ...... to myopathy in mice and humans
@nl
P1433
P1476
P2093
P304
P31
P3181
P356
P433
P478
P50
P577
P698
P921
P3181
P356
P1433
P1476
Cdk5rap1-mediated 2-methylthio ...... to myopathy in mice and humans
@en
P2093
P304
P31
P3181
P356
10.1016/J.CMET.2015.01.019
P433
P478
P50
P577
P698
P921