Two PDZ domain proteins encoded by the murine periaxin gene are the result of alternative intron retention and are differentially targeted in Schwann cells
about
Periaxin mutations cause recessive Dejerine-Sottas neuropathy.AHNAK interaction with the annexin 2/S100A10 complex regulates cell membrane cytoarchitectureNuclear export of L-periaxin, mediated by its nuclear export signal in the PDZ domainPeriaxin and AHNAK Nucleoprotein 2 Form Intertwined Homodimers through Domain SwappingA novel rat tetraspan protein in cells of the oligodendrocyte lineageEvolutionary conservation of a molecular machinery for export and expression of mRNAs with retained intronsMyelin-specific proteins: a structurally diverse group of membrane-interacting molecules.Intron retention generates a novel Id3 isoform that inhibits vascular lesion formation.Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells.A tripartite nuclear localization signal in the PDZ-domain protein L-periaxin.Syncoilin modulates peripherin filament networks and is necessary for large-calibre motor neurons.Periaxin mutations cause a broad spectrum of demyelinating neuropathies.The function of the Periaxin gene during nerve repair in a model of CMT4F.Understanding Schwann cell-neurone interactions: the key to Charcot-Marie-Tooth disease?Periaxin is required for hexagonal geometry and membrane organization of mature lens fibersAnkyrin-B directs membrane tethering of periaxin and is required for maintenance of lens fiber cell hexagonal shape and mechanics.Pathomechanisms of mutant proteins in Charcot-Marie-Tooth disease.Intermolecular disulfide bond in the dimerization of S-periaxin mediated by Cys88 and Cys139Schwann Cell O-GlcNAc Glycosylation Is Required for Myelin Maintenance and Axon Integrity.Demyelinating prenatal and infantile developmental neuropathies.Identification of a PRX variant in a Chinese family with congenital cataract by exome sequencing.Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy.Two separate domains in the golli myelin basic proteins are responsible for nuclear targeting and process extension in transfected cells.Increasing internodal distance in myelinated nerves accelerates nerve conduction to a flat maximum.Preliminary crystallographic analysis of the N-terminal PDZ-like domain of periaxin, an abundant peripheral nerve protein linked to human neuropathies.Differential amplification of intron-containing transcripts reveals long term potentiation-associated up-regulation of specific Pde10A phosphodiesterase splice variants.A Drosophila gene encoding multiple splice variants of Kazal-type serine protease inhibitor-like proteins with potential destinations of mitochondria, cytosol and the secretory pathway.The distribution pattern of genetic variation in the transcript isoforms of the alternatively spliced protein-coding genes in the human genome.A murine model of Charcot-Marie-Tooth disease 4F reveals a role for the C-terminus of periaxin in the formation and stabilization of Cajal bands.Intron retention in viruses and cellular genes: Detention, border controls and passports.Expression of periaxin (PRX) specifically in the human cerebrovascular system: PDZ domain-mediated strengthening of endothelial barrier function.
P2860
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P2860
Two PDZ domain proteins encoded by the murine periaxin gene are the result of alternative intron retention and are differentially targeted in Schwann cells
description
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1998
@ast
im März 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/03/06)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/03/06)
@nl
наукова стаття, опублікована в березні 1998
@uk
name
Two PDZ domain proteins encode ...... ally targeted in Schwann cells
@ast
Two PDZ domain proteins encode ...... ally targeted in Schwann cells
@en
Two PDZ domain proteins encode ...... ally targeted in Schwann cells
@nl
type
label
Two PDZ domain proteins encode ...... ally targeted in Schwann cells
@ast
Two PDZ domain proteins encode ...... ally targeted in Schwann cells
@en
Two PDZ domain proteins encode ...... ally targeted in Schwann cells
@nl
prefLabel
Two PDZ domain proteins encode ...... ally targeted in Schwann cells
@ast
Two PDZ domain proteins encode ...... ally targeted in Schwann cells
@en
Two PDZ domain proteins encode ...... ally targeted in Schwann cells
@nl
P2093
P356
P1476
Two PDZ domain proteins encode ...... ally targeted in Schwann cells
@en
P2093
C. S. Gillespie
D. L. Sherman
L. Dytrych
P. J. Brophy
P304
P356
10.1074/JBC.273.10.5794
P407
P577
1998-03-06T00:00:00Z