Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3
about
NSUN3 and ABH1 modify the wobble position of mt-tRNAMet to expand codon recognition in mitochondrial translationStructural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6Distinct 5-methylcytosine profiles in poly(A) RNA from mouse embryonic stem cells and brain.Maturation of selected human mitochondrial tRNAs requires deadenylation.Dealing with an Unconventional Genetic Code in Mitochondria: The Biogenesis and Pathogenic Defects of the 5-Formylcytosine Modification in Mitochondrial tRNAMet.Regulation of Mammalian Mitochondrial Gene Expression: Recent Advances.The Epitranscriptome of Noncoding RNAs in Cancer.ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modificationsGenetic diagnosis of Mendelian disorders via RNA sequencing.How RNA modification allows non-conventional decoding in mitochondriaMacropinocytic entry of isolated mitochondria in epidermal growth factor-activated human osteosarcoma cells.Methionine on the rise: how mitochondria changed their codon usage.Epitranscriptomic influences on development and disease.A hypertension-associated mitochondrial DNA mutation introduces an m1G37 modification into tRNAMet, altering its structure and function.Mutations in RNA methylating enzymes in disease.MODOMICS: a database of RNA modification pathways. 2017 update.RNA cytosine methyltransferase Nsun3 regulates embryonic stem cell differentiation by promoting mitochondrial activity.Detection of nucleic acid modifications by chemical reagents.Heterozygous SSBP1 start loss mutation co-segregates with hearing loss and the m.1555A>G mtDNA variant in a large multigenerational family.Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease.Mitochondrial translation requires folate-dependent tRNA methylation.Defective mitochondrial rRNA methyltransferase MRM2 causes MELAS-like clinical syndrome.The mitochondrial epitranscriptome: the roles of RNA modifications in mitochondrial translation and human disease.Reversible RNA modifications in meiosis and pluripotency.Synthesis and Multiple Incorporations of 2'-O-Methyl-5-hydroxymethylcytidine, 5-Hydroxymethylcytidine and 5-Formylcytidine Monomers into RNA Oligonucleotides.OCR-Stats: Robust estimation and statistical testing of mitochondrial respiration activities using Seahorse XF Analyzer.
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P2860
Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3
description
2016 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans Nature Communications
@fr
artículu científicu espublizáu en 2016
@ast
im Juni 2016 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2016/06/30)
@sk
vědecký článek publikovaný v roce 2016
@cs
wetenschappelijk artikel (gepubliceerd op 2016/06/30)
@nl
наукова стаття, опублікована в червні 2016
@uk
name
Deficient methylation and form ...... nt carrying mutations in NSUN3
@ast
Deficient methylation and form ...... nt carrying mutations in NSUN3
@en
Deficient methylation and form ...... nt carrying mutations in NSUN3
@nl
type
label
Deficient methylation and form ...... nt carrying mutations in NSUN3
@ast
Deficient methylation and form ...... nt carrying mutations in NSUN3
@en
Deficient methylation and form ...... nt carrying mutations in NSUN3
@nl
prefLabel
Deficient methylation and form ...... nt carrying mutations in NSUN3
@ast
Deficient methylation and form ...... nt carrying mutations in NSUN3
@en
Deficient methylation and form ...... nt carrying mutations in NSUN3
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Deficient methylation and form ...... nt carrying mutations in NSUN3
@en
P2093
Anja Kolb-Kokocinski
Georg F Hoffmann
Laura Kremer
Lindsey Van Haute
Sabine Dietmann
Sarah F Pearce
Sascha Sauer
Shobbir Hussain
Urania Kotzaeridou
Yasin Memari
P2860
P2888
P3181
P356
10.1038/NCOMMS12039
P407
P50
P577
2016-06-30T00:00:00Z
P6179
1029054809