Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer
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Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolismTCA Cycle Nutrient Utilization and Invasiveness of Ovarian CancerGlutamine promotes ovarian cancer cell proliferation through the mTOR/S6 pathway.Role of Increased n-acetylaspartate Levels in Cancer.AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion.Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cellsFrom Krebs to clinic: glutamine metabolism to cancer therapy.Serine hydroxymethyl transferase 1 stimulates pro-oncogenic cytokine expression through sialic acid to promote ovarian cancer tumor growth and progressionFlux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism.Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism.Famine versus feast: understanding the metabolism of tumors in vivo.Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients.Synthetic dosage lethality in the human metabolic network is highly predictive of tumor growth and cancer patient survival.Low-mass-ion discriminant equation (LOME) for ovarian cancer screening.Nitric oxide is a positive regulator of the Warburg effect in ovarian cancer cellsMetabolic plasticity of metastatic breast cancer cells: adaptation to changes in the microenvironment.NRP1 is targeted by miR-130a and miR-130b, and is associated with multidrug resistance in epithelial ovarian cancer based on integrated gene network analysis.Coupling the modules of EMT and stemness: A tunable 'stemness window' modelResistance to BRAF inhibitors induces glutamine dependency in melanoma cellsHSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancerDirect Upregulation of STAT3 by MicroRNA-551b-3p Deregulates Growth and Metastasis of Ovarian Cancer.Fast exchange fluxes around the pyruvate node: a leaky cell model to explain the gain and loss of unlabelled and labelled metabolites in a tracer experiment.The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment.Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer.Glutaminase inhibitor compound 968 inhibits cell proliferation and sensitizes paclitaxel in ovarian cancerAmplification of USP13 drives ovarian cancer metabolism.Altered glutamine metabolism in platinum resistant ovarian cancer.Glutamine activates STAT3 to control cancer cell proliferation independently of glutamine metabolism.The ELK3-GATA3 axis orchestrates invasion and metastasis of breast cancer cells in vitro and in vivo.Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma.Germline compound heterozygous poly-glutamine deletion in USF3 may be involved in predisposition to heritable and sporadic epithelial thyroid carcinomaHeterogeneity in Cancer Metabolism: New Concepts in an Old Field.The Glutamate Dehydrogenase Pathway and Its Roles in Cell and Tissue Biology in Health and Disease.Glutamine at focus: versatile roles in cancer.Blockage of glutaminolysis enhances the sensitivity of ovarian cancer cells to PI3K/mTOR inhibition involvement of STAT3 signaling.Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells.CD90(+) stromal cells are the major source of IL-6, which supports cancer stem-like cells and inflammation in colorectal cancer.(1)H MRS: a potential biomarker of in utero placental function.Bioenergetic Adaptations in Chemoresistant Ovarian Cancer Cells.Expression and prognostic value of glutamate dehydrogenase in extrahepatic cholangiocarcinoma patients.
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P2860
Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer
description
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2014
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im Mai 2014 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2014/05/05)
@sk
vědecký článek publikovaný v roce 2014
@cs
wetenschappelijk artikel (gepubliceerd op 2014/05/05)
@nl
наукова стаття, опублікована в травні 2014
@uk
مقالة علمية (نشرت في 5-5-2014)
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name
Metabolic shifts toward glutam ...... ioenergetics in ovarian cancer
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Metabolic shifts toward glutam ...... ioenergetics in ovarian cancer
@en
Metabolic shifts toward glutam ...... ioenergetics in ovarian cancer
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type
label
Metabolic shifts toward glutam ...... ioenergetics in ovarian cancer
@ast
Metabolic shifts toward glutam ...... ioenergetics in ovarian cancer
@en
Metabolic shifts toward glutam ...... ioenergetics in ovarian cancer
@nl
prefLabel
Metabolic shifts toward glutam ...... ioenergetics in ovarian cancer
@ast
Metabolic shifts toward glutam ...... ioenergetics in ovarian cancer
@en
Metabolic shifts toward glutam ...... ioenergetics in ovarian cancer
@nl
P2093
P2860
P50
P3181
P356
P1476
Metabolic shifts toward glutam ...... ioenergetics in ovarian cancer
@en
P2093
Anil K Sood
Dahai Jiang
Gabriel Lopez-Berestein
Hongyun Zhao
Imelda Mercado-Uribe
Jinsong Liu
Juan Marini
Lifeng Yang
Lingegowda S Mangala
P2860
P3181
P356
10.1002/MSB.20134892
P50
P577
2014-05-05T00:00:00Z