Use of a small molecule cell cycle inhibitor to control cell growth and improve specific productivity and product quality of recombinant proteins in CHO cell cultures

Use of a small molecule cell cycle inhibitor to control cell growth and improve specific productivity and product quality of recombinant proteins in CHO cell cultures

Item
http://www.wikidata.org/entity/Q28652788
Enhanced recombinant factor VII expression in Chinese hamster ovary cells by optimizing signal peptides and fed-batch medium.Tailoring recombinant protein quality by rational media design.High throughput screening identifies novel, cell cycle-arresting small molecule enhancers of transient protein expression.Principles and approach to developing mammalian cell culture media for high cell density perfusion process leveraging established fed-batch media.Cellular engineering for therapeutic protein production: product quality, host modification, and process improvement.The molecular weight and concentration of dextran sulfate affect cell growth and antibody production in CHO cell cultures.Disruption of the gene C12orf35 leads to increased productivities in recombinant CHO cell lines.A control strategy to investigate the relationship between specific productivity and high-mannose glycoforms in CHO cells.Real-time product attribute control to manufacture antibodies with defined N-linked glycan levels.Main Quality Attributes of Monoclonal Antibodies and Effect of Cell Culture ComponentsOn-Line Control of Glucose Concentration in High-Yielding Mammalian Cell Cultures Enabled Through Oxygen Transfer Rate Measurements.Strategies and Considerations for Improving Expression of "Difficult to Express" Proteins in CHO Cells.Cell-controlled hybrid perfusion fed-batch CHO cell process provides significant productivity improvement over conventional fed-batch cultures.Valeric acid induces cell cycle arrest at G1 phase in CHO cell cultures and improves recombinant antibody productivity.Understanding the intracellular effects of yeast extract on the enhancement of Fc-fusion protein production in Chinese hamster ovary cell culture.Integrated cell and process engineering for improved transient production of a "difficult-to-express" fusion protein by CHO cells.Cell Line Techniques and Gene Editing Tools for Antibody Production: A Review.
P2860

Use of a small molecule cell cycle inhibitor to control cell growth and improve specific productivity and product quality of recombinant proteins in CHO cell cultures

Item
http://www.wikidata.org/entity/Q28652788
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2015 nî lūn-bûn
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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2015 թվականի հունվարին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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name
Use of a small molecule cell c ...... proteins in CHO cell cultures
@ast
Use of a small molecule cell c ...... proteins in CHO cell cultures
@en
Use of a small molecule cell c ...... proteins in CHO cell cultures
@nl
type
label
Use of a small molecule cell c ...... proteins in CHO cell cultures
@ast
Use of a small molecule cell c ...... proteins in CHO cell cultures
@en
Use of a small molecule cell c ...... proteins in CHO cell cultures
@nl
prefLabel
Use of a small molecule cell c ...... proteins in CHO cell cultures
@ast
Use of a small molecule cell c ...... proteins in CHO cell cultures
@en
Use of a small molecule cell c ...... proteins in CHO cell cultures
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Use of a small molecule cell c ...... proteins in CHO cell cultures
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932