Epithelial-mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2
about
Mutations in GRHL2 result in an autosomal-recessive ectodermal Dysplasia syndromeMechanisms of TGFβ-Induced Epithelial-Mesenchymal TransitionThe DACH/EYA/SIX gene network and its role in tumor initiation and progressionGrainyhead-like 2 Reverses the Metabolic Changes Induced by the Oncogenic Epithelial-Mesenchymal Transition: Effects on AnoikisGrainyhead-like 2 inhibits the coactivator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition.Mesenchymal to amoeboid transition is associated with stem-like features of melanoma cells.Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?Downregulation of GRHL2 inhibits the proliferation of colorectal cancer cells by targeting ZEB1GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancer.Highly adaptable triple-negative breast cancer cells as a functional model for testing anticancer agents.Stability of the hybrid epithelial/mesenchymal phenotype.Homeoprotein Six2 promotes breast cancer metastasis via transcriptional and epigenetic control of E-cadherin expression.Expression of transcription factor grainyhead-like 2 is diminished in cervical cancer.An axis involving SNAI1, microRNA-128 and SP1 modulates glioma progression.A Histone Deacetylase Inhibitor Suppresses Epithelial-Mesenchymal Transition and Attenuates Chemoresistance in Biliary Tract Cancer.The p63 Gene Is Regulated by Grainyhead-like 2 (GRHL2) through Reciprocal Feedback and Determines the Epithelial Phenotype in Human KeratinocytesTranscriptome Sequencing (RNAseq) Enables Utilization of Formalin-Fixed, Paraffin-Embedded Biopsies with Clear Cell Renal Cell Carcinoma for Exploration of Disease Biology and Biomarker Development.MicroRNA networks regulated by all-trans retinoic acid and Lapatinib control the growth, survival and motility of breast cancer cellsGRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification.Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure.Grhl3 induces human epithelial tumor cell migration and invasion via downregulation of E-cadherinRecent discoveries concerning the involvement of transcription factors from the Grainyhead-like family in cancerMesenchymal-Epithelial Transition in Sarcomas Is Controlled by the Combinatorial Expression of MicroRNA 200s and GRHL2.Grhl2 reduces invasion and migration through inhibition of TGFβ-induced EMT in gastric cancer.Suppression of the grainyhead transcription factor 2 gene (GRHL2) inhibits the proliferation, migration, invasion and mediates cell cycle arrest of ovarian cancer cells.Diverse expression patterns of the EMT suppressor grainyhead-like 2 (GRHL2) in normal and tumour tissues.A Grainyhead-Like 2/Ovo-Like 2 Pathway Regulates Renal Epithelial Barrier Function and Lumen Expansion.STAT3-Mediated Metabolic Reprograming in Cellular Transformation and Implications for Drug ResistanceDNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells.A Network Biology Approach Identifies Molecular Cross-Talk between Normal Prostate Epithelial and Prostate Carcinoma Cells.Grainyhead-like 2 regulates epithelial plasticity and stemness in oral cancer cells.CD44S-hyaluronan interactions protect cells resulting from EMT against anoikis.The GRHL2/ZEB Feedback Loop-A Key Axis in the Regulation of EMT in Breast Cancer.Interplay Between Transcription Factors and MicroRNAs Regulating Epithelial-Mesenchymal Transitions in Colorectal Cancer.Stable Binding of the Conserved Transcription Factor Grainy Head to its Target Genes Throughout Drosophila melanogaster Development.Grainyhead-like 2 in development and cancer.Epithelial-mesenchymal transition, a spectrum of states: Role in lung development, homeostasis, and disease.Roles of Grainyhead-like transcription factors in cancer.Phenotypic screening identifies Axl kinase as a negative regulator of an alveolar epithelial cell phenotype.SIX1 Oncoprotein as a Biomarker in a Model of Hormonal Carcinogenesis and in Human Endometrial Cancer.
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P2860
Epithelial-mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Epithelial-mesenchymal transit ...... een ZEB1 and Grainyhead-like-2
@ast
Epithelial-mesenchymal transit ...... een ZEB1 and Grainyhead-like-2
@en
Epithelial-mesenchymal transit ...... een ZEB1 and Grainyhead-like-2
@nl
type
label
Epithelial-mesenchymal transit ...... een ZEB1 and Grainyhead-like-2
@ast
Epithelial-mesenchymal transit ...... een ZEB1 and Grainyhead-like-2
@en
Epithelial-mesenchymal transit ...... een ZEB1 and Grainyhead-like-2
@nl
prefLabel
Epithelial-mesenchymal transit ...... een ZEB1 and Grainyhead-like-2
@ast
Epithelial-mesenchymal transit ...... een ZEB1 and Grainyhead-like-2
@en
Epithelial-mesenchymal transit ...... een ZEB1 and Grainyhead-like-2
@nl
P2093
P2860
P3181
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Epithelial-mesenchymal transit ...... een ZEB1 and Grainyhead-like-2
@en
P2093
Benjamin Cieply
Heide L Ford
James Denvir
Joshua Farris
Steven M Frisch
P2860
P304
P3181
P356
10.1158/0008-5472.CAN-12-4082
P407
P577
2013-10-15T00:00:00Z