Contact sensitizers induce skin inflammation via ROS production and hyaluronic acid degradation
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Biomaterial Applications in Cell-Based Therapy in Experimental StrokeNew genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivityIdiosyncratic adverse drug reactions: current conceptsMajor pathophysiological correlations of rosacea: a complete clinical appraisalSynergistic effect between amoxicillin and TLR ligands on dendritic cells from amoxicillin-delayed allergic patientsAnchoring molecular mechanisms to the adverse outcome pathway for skin sensitization: Analysis of existing data.Extracellular matrix regulation of inflammation in the healthy and injured spinal cordThe antioxidative effect of heat-shock protein 70 in dendritic cells.Neutrophils are required for both the sensitization and elicitation phase of contact hypersensitivityOxazolone-induced contact hypersensitivity reduces lymphatic drainage but enhances the induction of adaptive immunity.The Hyaluronic Acid-HDAC3-miRNA Network in Allergic Inflammation.Immunoproteomic identification and characterization of Ni2+-regulated proteins implicates Ni2+ in the induction of monocyte cell death.Endotoxin free hyaluronan and hyaluronan fragments do not stimulate TNF-α, interleukin-12 or upregulate co-stimulatory molecules in dendritic cells or macrophages.Why does allergic contact dermatitis exist?In vitro approaches for detection of chemical sensitization.Prediction of skin sensitizers using alternative methods to animal experimentation.Adaptation in the innate immune system and heterologous innate immunity.Hyaluronan and RHAMM in wound repair and the "cancerization" of stromal tissues.Sugars in the microenvironment: the sticky problem of HA turnover in tumors.New concepts in cutaneous allergy.Genetic factors in susceptibility to contact sensitivity.The where, when, how, and why of hyaluronan binding by immune cells.Contact dermatitis: a comparative and translational review of the literature.Reporter cell lines for skin sensitization testing.Inhibition of Hyaluronan Synthesis Attenuates Pulmonary Hypertension Associated with Lung Fibrosis.Immunology and genetics of tumour necrosis factor in allergic contact dermatitis.Skin sensitizers in cosmetics and beyond: potential multiple mechanisms of action and importance of T-cell assays for in vitro screening.Thiram modulates pro-inflammatory mediators in RAW 264.7 murine macrophage cells.The involvement of the Toll-like receptor signaling and Nrf2-Keap1 pathways in the in vitro regulation of IL-8 and HMOX1 for skin sensitization.Low dose ultraviolet B irradiation increases hyaluronan synthesis in epidermal keratinocytes via sequential induction of hyaluronan synthases Has1-3 mediated by p38 and Ca2+/calmodulin-dependent protein kinase II (CaMKII) signaling.Immunological, chemical and clinical aspects of exposure to mixtures of contact allergens.Chemical or drug hypersensitivity: is the immune system clearing the danger?Bayesian integrated testing strategy (ITS) for skin sensitization potency assessment: a decision support system for quantitative weight of evidence and adaptive testing strategy.A Dose-Response Modeling Approach Shows That Effects From Mixture Exposure to the Skin Sensitizers Isoeugenol and Cinnamal Are in Line With Dose Addition and Not With Synergism.Evaluation of hyaluronic acid-P40 conjugated cream in a mouse model of dermatitis induced by oxazolone.Allergic skin inflammation induced by chemical sensitizers is controlled by the transcription factor Nrf2.Induction of skin sensitization is augmented in Nrf2-deficient mice.Pathomechanisms of Contact Sensitization.Characterization of Drug-Specific Signaling Between Primary Human Hepatocytes and Immune Cells.Treatment with the hyaluronic Acid synthesis inhibitor 4-methylumbelliferone suppresses LPS-induced lung inflammation.
P2860
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P2860
Contact sensitizers induce skin inflammation via ROS production and hyaluronic acid degradation
description
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique PLoS ONE
@fr
artículu científicu espublizáu en 2012
@ast
im Januar 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 2012)
@en
vedecký článok (publikovaný 2012)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd in 2012)
@nl
наукова стаття, опублікована у 2012
@uk
name
Contact sensitizers induce ski ...... nd hyaluronic acid degradation
@ast
Contact sensitizers induce ski ...... nd hyaluronic acid degradation
@en
Contact sensitizers induce ski ...... nd hyaluronic acid degradation
@nl
type
label
Contact sensitizers induce ski ...... nd hyaluronic acid degradation
@ast
Contact sensitizers induce ski ...... nd hyaluronic acid degradation
@en
Contact sensitizers induce ski ...... nd hyaluronic acid degradation
@nl
prefLabel
Contact sensitizers induce ski ...... nd hyaluronic acid degradation
@ast
Contact sensitizers induce ski ...... nd hyaluronic acid degradation
@en
Contact sensitizers induce ski ...... nd hyaluronic acid degradation
@nl
P2093
P2860
P3181
P1433
P1476
Contact sensitizers induce ski ...... nd hyaluronic acid degradation
@en
P2093
Christoph Dürr
Christoph M Schempp
Friederike D von Loewenich
Marina A Freudenberg
Stefan F Martin
Thilo Jakob
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0041340
P407
P577
2012-07-25T00:00:00Z