The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanoma
about
Anti-Cancer Stem-like Cell Compounds in Clinical Development - An Overview and Critical AppraisalOther targeted drugs in melanomaFrom fly wings to targeted cancer therapies: a centennial for notch signalingPotential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseasesAnti-miR182 reduces ovarian cancer burden, invasion, and metastasis: an in vivo study in orthotopic xenografts of nude mice.Insulin-Producing Endocrine Cells Differentiated In Vitro From Human Embryonic Stem Cells Function in Macroencapsulation Devices In Vivo.Cancer stem cells and chemoresistance: The smartest survives the raidCancer stem cells and tumor transdifferentiation: implications for novel therapeutic strategies.Identification of a Novel Pathogenic Germline KDR Variant in Melanoma.Chemotherapy in the management of advanced cutaneous malignant melanoma.Anti-myeloma effect of pharmacological inhibition of Notch/gamma-secretase with RO4929097 is mediated by modulation of tumor microenvironment.Hedgehog pathway blockade inhibits melanoma cell growth in vitro and in vivo.Altered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies.Notch activation stimulates migration of breast cancer cells and promotes tumor growthCombining a GSI and BCL-2 inhibitor to overcome melanoma's resistance to current treatments.Notch3 signaling-mediated melanoma-endothelial crosstalk regulates melanoma stem-like cell homeostasis and niche morphogenesis.Gamma secretase inhibitors: a patent review (2013 - 2015).Approaches for targeting cancer stem cells drug resistance.Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma.Novel Small Molecule Inhibitors of Cancer Stem Cell Signaling Pathways.Targeting Notch signalling pathway of cancer stem cells.Opposing role of Notch1 and Notch2 in a KrasG12D-driven murine non-small cell lung cancer model
P2860
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P2860
The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanoma
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
The novel gamma secretase inhi ...... itiating potential of melanoma
@ast
The novel gamma secretase inhi ...... itiating potential of melanoma
@en
The novel gamma secretase inhi ...... itiating potential of melanoma
@nl
type
label
The novel gamma secretase inhi ...... itiating potential of melanoma
@ast
The novel gamma secretase inhi ...... itiating potential of melanoma
@en
The novel gamma secretase inhi ...... itiating potential of melanoma
@nl
prefLabel
The novel gamma secretase inhi ...... itiating potential of melanoma
@ast
The novel gamma secretase inhi ...... itiating potential of melanoma
@en
The novel gamma secretase inhi ...... itiating potential of melanoma
@nl
P2093
P2860
P50
P3181
P1433
P1476
The novel gamma secretase inhi ...... itiating potential of melanoma
@en
P2093
Adele Haimovic
Anna Pavlick
Chanh Huynh
Farbod Darvishian
Iman Osman
John F Boylan
Ratna Medicherla
Shulian Shang
Silvia Menendez
Yongzhao Shao
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0025264
P407
P577
2011-01-01T00:00:00Z